CA3239503A1 - Rapid t-cell manufacturing - Google Patents

Rapid t-cell manufacturing Download PDF

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Publication number
CA3239503A1
CA3239503A1 CA3239503A CA3239503A CA3239503A1 CA 3239503 A1 CA3239503 A1 CA 3239503A1 CA 3239503 A CA3239503 A CA 3239503A CA 3239503 A CA3239503 A CA 3239503A CA 3239503 A1 CA3239503 A1 CA 3239503A1
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Canada
Prior art keywords
cells
cell
cell population
activator
manufacturing
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Pending
Application number
CA3239503A
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English (en)
French (fr)
Inventor
David Wald
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kure Ai Inc
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Kure Ai Inc
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Publication of CA3239503A1 publication Critical patent/CA3239503A1/en
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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    • C12N2501/50—Cell markers; Cell surface determinants
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/10041—Use of virus, viral particle or viral elements as a vector
    • C12N2740/10043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
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    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
    • C12N2740/15041—Use of virus, viral particle or viral elements as a vector
    • C12N2740/15043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16041—Use of virus, viral particle or viral elements as a vector
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    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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  • Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
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  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA3239503A 2021-12-22 2022-12-22 Rapid t-cell manufacturing Pending CA3239503A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163292843P 2021-12-22 2021-12-22
US63/292,843 2021-12-22
PCT/US2022/053815 WO2023122277A2 (en) 2021-12-22 2022-12-22 Rapid t-cell manufacturing

Publications (1)

Publication Number Publication Date
CA3239503A1 true CA3239503A1 (en) 2023-06-29

Family

ID=86903666

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3239503A Pending CA3239503A1 (en) 2021-12-22 2022-12-22 Rapid t-cell manufacturing

Country Status (14)

Country Link
US (1) US20250027042A1 (enExample)
EP (2) EP4453188A4 (enExample)
JP (2) JP2024546145A (enExample)
KR (1) KR20240123837A (enExample)
CN (1) CN119698465A (enExample)
AR (2) AR128077A1 (enExample)
AU (1) AU2022422123A1 (enExample)
CA (1) CA3239503A1 (enExample)
CL (1) CL2024001919A1 (enExample)
CO (1) CO2024008914A2 (enExample)
IL (1) IL313516A (enExample)
MX (1) MX2024007669A (enExample)
UY (1) UY40089A (enExample)
WO (2) WO2023122277A2 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119698465A (zh) * 2021-12-22 2025-03-25 克尔人工智能公司 快速t细胞制造
KR20260096851A (ko) 2023-10-18 2026-06-24 티큐 테라퓨틱스 게엠베하 세포 치료제 제조 방법 및 관련 키트와 장치
EP4725578A1 (en) 2024-10-08 2026-04-15 TQ Therapeutics GmbH Column designs for affinity chromatography

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5244806A (en) * 1985-08-26 1993-09-14 Eli Lilly And Company DNA encoding novel tissue plasminogen activator derivatives having kringles 1 and 2 deleted, vectors and host cells
CN108884460B (zh) * 2016-03-19 2023-04-28 埃克苏马生物技术公司 淋巴细胞转导及其扩增调节的方法与组合物
GB201622044D0 (en) * 2016-12-22 2017-02-08 Ucl Business Plc T cell-targeted T cells
CN113840911A (zh) * 2018-09-02 2021-12-24 埃克苏马生物技术公司 用于在血液中或在富集pbmc中基因修饰淋巴细胞的方法和组合物
CN119698465A (zh) * 2021-12-22 2025-03-25 克尔人工智能公司 快速t细胞制造

Also Published As

Publication number Publication date
WO2024136920A4 (en) 2025-06-12
AR128077A1 (es) 2024-03-20
WO2023122277A2 (en) 2023-06-29
AR130098A1 (es) 2024-11-06
CO2024008914A2 (es) 2024-08-08
AU2022422123A1 (en) 2024-07-11
CL2024001919A1 (es) 2024-12-06
IL313516A (en) 2024-08-01
EP4453188A4 (en) 2025-12-03
CN119698465A (zh) 2025-03-25
WO2023122277A3 (en) 2023-08-24
WO2024136920A1 (en) 2024-06-27
MX2024007669A (es) 2024-07-09
EP4453188A2 (en) 2024-10-30
UY40089A (es) 2023-07-14
US20250027042A1 (en) 2025-01-23
JP2024546145A (ja) 2024-12-17
EP4638711A1 (en) 2025-10-29
KR20240123837A (ko) 2024-08-14
JP2026501322A (ja) 2026-01-14

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