CA3223723A1 - Circulating microrna signatures for pancreatic cancer - Google Patents

Circulating microrna signatures for pancreatic cancer Download PDF

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Publication number
CA3223723A1
CA3223723A1 CA3223723A CA3223723A CA3223723A1 CA 3223723 A1 CA3223723 A1 CA 3223723A1 CA 3223723 A CA3223723 A CA 3223723A CA 3223723 A CA3223723 A CA 3223723A CA 3223723 A1 CA3223723 A1 CA 3223723A1
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CA
Canada
Prior art keywords
hsa
seq
mir
quantifying
specifically hybridizes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3223723A
Other languages
English (en)
French (fr)
Inventor
Dipanjan Chowdhury
Wojciech FENDLER
Konrad STAWISKI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medical University Of Lodz
Dana Farber Cancer Institute Inc
Original Assignee
Medical University Of Lodz
Dana Farber Cancer Institute Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medical University Of Lodz, Dana Farber Cancer Institute Inc filed Critical Medical University Of Lodz
Publication of CA3223723A1 publication Critical patent/CA3223723A1/en
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6851Quantitative amplification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/166Oligonucleotides used as internal standards, controls or normalisation probes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/178Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA3223723A 2021-07-09 2022-07-09 Circulating microrna signatures for pancreatic cancer Pending CA3223723A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163220195P 2021-07-09 2021-07-09
US63/220,195 2021-07-09
PCT/US2022/036608 WO2023283476A2 (en) 2021-07-09 2022-07-09 Circulating microrna signatures for pancreatic cancer

Publications (1)

Publication Number Publication Date
CA3223723A1 true CA3223723A1 (en) 2023-01-12

Family

ID=84801035

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3223723A Pending CA3223723A1 (en) 2021-07-09 2022-07-09 Circulating microrna signatures for pancreatic cancer

Country Status (6)

Country Link
US (1) US20250092460A1 (enExample)
EP (1) EP4367257A4 (enExample)
JP (1) JP2024527370A (enExample)
AU (1) AU2022306397A1 (enExample)
CA (1) CA3223723A1 (enExample)
WO (1) WO2023283476A2 (enExample)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014055117A1 (en) * 2012-10-04 2014-04-10 Asuragen, Inc. Diagnostic mirnas for differential diagnosis of incidental pancreatic cystic lesions
CN105102637B (zh) * 2013-04-17 2018-05-22 Lg电子株式会社 提取胰腺癌诊断生物标志物的方法、用于该方法的计算装置、胰腺癌诊断生物标志物以及包含该生物标志物的胰腺癌诊断装置
CA3018048A1 (en) * 2016-03-31 2017-10-05 Toray Industries, Inc. Kit or device for detecting early stage pancreatic cancer or pancreatic cancer precursor lesions and detection method therefor
WO2018129535A1 (en) * 2017-01-09 2018-07-12 Dana-Farber Cancer Institute, Inc. Circulating microrna signatures for ovarian cancer
BR102018003587A2 (pt) * 2018-02-23 2020-07-07 Onkos Diagnósticos Moleculares Ltda Me método e kit para detecção de tipo de tumor de tireoide
CN109055557B (zh) * 2018-09-11 2022-11-29 朱伟 一种与胰腺癌辅助诊断相关的血清miRNA标志物及其应用

Also Published As

Publication number Publication date
JP2024527370A (ja) 2024-07-24
AU2022306397A1 (en) 2024-01-25
WO2023283476A2 (en) 2023-01-12
WO2023283476A3 (en) 2023-03-09
EP4367257A2 (en) 2024-05-15
US20250092460A1 (en) 2025-03-20
WO2023283476A9 (en) 2023-11-23
EP4367257A4 (en) 2025-10-15

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