JP2024527370A - 膵臓がんに対する循環マイクロｒｎａシグネチャ - Google Patents

膵臓がんに対する循環マイクロｒｎａシグネチャ Download PDF

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JP2024527370A
JP2024527370A JP2024500606A JP2024500606A JP2024527370A JP 2024527370 A JP2024527370 A JP 2024527370A JP 2024500606 A JP2024500606 A JP 2024500606A JP 2024500606 A JP2024500606 A JP 2024500606A JP 2024527370 A JP2024527370 A JP 2024527370A
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hsa
seq
mir
quantifying
specifically hybridizes
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JP2024527370A5 (enExample
Inventor
チャウドリー，ディパンジャン
フェンドラー，ヴォイチェフ
スタウィスキ，コンラッド
Original Assignee
ダナ－ファーバー キャンサー インスティテュート， インコーポレイテッド
メディカル ユニバーシティ オブ ウッチ
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Publication of JP2024527370A publication Critical patent/JP2024527370A/ja
Publication of JP2024527370A5 publication Critical patent/JP2024527370A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6851—Quantitative amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/166—Oligonucleotides used as internal standards, controls or normalisation probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2024500606A 2021-07-09 2022-07-09 膵臓がんに対する循環マイクロｒｎａシグネチャ Pending JP2024527370A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163220195P 2021-07-09 2021-07-09
US63/220,195 2021-07-09
PCT/US2022/036608 WO2023283476A2 (en) 2021-07-09 2022-07-09 Circulating microrna signatures for pancreatic cancer

Publications (2)

Publication Number Publication Date
JP2024527370A true JP2024527370A (ja) 2024-07-24
JP2024527370A5 JP2024527370A5 (enExample) 2025-07-31

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ID=84801035

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JP2024500606A Pending JP2024527370A (ja) 2021-07-09 2022-07-09 膵臓がんに対する循環マイクロｒｎａシグネチャ

Country Status (6)

Country Link
US (1) US20250092460A1 (enExample)
EP (1) EP4367257A4 (enExample)
JP (1) JP2024527370A (enExample)
AU (1) AU2022306397A1 (enExample)
CA (1) CA3223723A1 (enExample)
WO (1) WO2023283476A2 (enExample)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014055117A1 (en) * 2012-10-04 2014-04-10 Asuragen, Inc. Diagnostic mirnas for differential diagnosis of incidental pancreatic cystic lesions
CN105102637B (zh) * 2013-04-17 2018-05-22 Lg电子株式会社 提取胰腺癌诊断生物标志物的方法、用于该方法的计算装置、胰腺癌诊断生物标志物以及包含该生物标志物的胰腺癌诊断装置
CA3018048A1 (en) * 2016-03-31 2017-10-05 Toray Industries, Inc. Kit or device for detecting early stage pancreatic cancer or pancreatic cancer precursor lesions and detection method therefor
WO2018129535A1 (en) * 2017-01-09 2018-07-12 Dana-Farber Cancer Institute, Inc. Circulating microrna signatures for ovarian cancer
BR102018003587A2 (pt) * 2018-02-23 2020-07-07 Onkos Diagnósticos Moleculares Ltda Me método e kit para detecção de tipo de tumor de tireoide
CN109055557B (zh) * 2018-09-11 2022-11-29 朱伟 一种与胰腺癌辅助诊断相关的血清miRNA标志物及其应用

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Publication number Publication date
AU2022306397A1 (en) 2024-01-25
WO2023283476A2 (en) 2023-01-12
WO2023283476A3 (en) 2023-03-09
EP4367257A2 (en) 2024-05-15
US20250092460A1 (en) 2025-03-20
WO2023283476A9 (en) 2023-11-23
CA3223723A1 (en) 2023-01-12
EP4367257A4 (en) 2025-10-15

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