CA3222017A1 - Strain for producing highly concentrated l-glutamic acid, and l-glutamic acid production method using same - Google Patents

Strain for producing highly concentrated l-glutamic acid, and l-glutamic acid production method using same Download PDF

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Publication number
CA3222017A1
CA3222017A1 CA3222017A CA3222017A CA3222017A1 CA 3222017 A1 CA3222017 A1 CA 3222017A1 CA 3222017 A CA3222017 A CA 3222017A CA 3222017 A CA3222017 A CA 3222017A CA 3222017 A1 CA3222017 A1 CA 3222017A1
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Canada
Prior art keywords
microorganism
sequence
glutamic acid
protein
polypeptide
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Pending
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CA3222017A
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English (en)
French (fr)
Inventor
Nara Kwon
Hyun-Ju BONG
Jin Nam Lee
Ah Reum Lee
Jung Ok HEO
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CJ CheilJedang Corp
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Individual
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Publication of CA3222017A1 publication Critical patent/CA3222017A1/en
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0008Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0093Oxidoreductases (1.) acting on CH or CH2 groups (1.17)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/14Glutamic acid; Glutamine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/15Corynebacterium
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y102/00Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/04Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with a disulfide as acceptor (1.2.4)
    • C12Y102/04002Oxoglutarate dehydrogenase (succinyl-transferring) (1.2.4.2), i.e. alpha-ketoglutarat dehydrogenase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y117/00Oxidoreductases acting on CH or CH2 groups (1.17)

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
CA3222017A 2021-06-30 2022-03-31 Strain for producing highly concentrated l-glutamic acid, and l-glutamic acid production method using same Pending CA3222017A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR10-2021-0085738 2021-06-30
KR1020210085738A KR102665227B1 (ko) 2021-06-30 2021-06-30 고농도 l-글루탐산을 생산하기 위한 균주 및 이를 이용한 l-글루탐산 생산방법
PCT/KR2022/004562 WO2023277307A1 (ko) 2021-06-30 2022-03-31 고농도 l-글루탐산을 생산하기 위한 균주 및 이를 이용한 l-글루탐산 생산방법

Publications (1)

Publication Number Publication Date
CA3222017A1 true CA3222017A1 (en) 2023-01-05

Family

ID=84690383

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3222017A Pending CA3222017A1 (en) 2021-06-30 2022-03-31 Strain for producing highly concentrated l-glutamic acid, and l-glutamic acid production method using same

Country Status (12)

Country Link
US (1) US20240218381A1 (de)
EP (1) EP4349991A4 (de)
JP (1) JP7690070B2 (de)
KR (1) KR102665227B1 (de)
CN (1) CN118369433A (de)
AR (1) AR125493A1 (de)
AU (1) AU2022302574B2 (de)
CA (1) CA3222017A1 (de)
MX (1) MX2023015552A (de)
TW (1) TWI819552B (de)
WO (1) WO2023277307A1 (de)
ZA (1) ZA202311686B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102730434B1 (ko) * 2021-09-23 2024-11-14 씨제이제일제당 주식회사 고농도 l-글루탐산을 생산하기 위한 균주 및 이를 이용한 l-글루탐산 생산방법
KR20240169179A (ko) * 2023-05-23 2024-12-03 씨제이제일제당 (주) 글루타메이트 계열 아미노산 생산 미생물 및 이를 이용한 글루타메이트 계열 아미노산 생산 방법

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3220929A (en) 1964-02-10 1965-11-30 Kyowa Hakko Kogyo Kk Microbiological production of amino acid by reductive amination
AU746542B2 (en) 1998-03-18 2002-05-02 Ajinomoto Co., Inc. L-glutamic acid-producing bacterium and method for producing L-glutamic acid
KR100292299B1 (ko) 1999-03-22 2001-06-01 손경식 글루탐산 생산 미생물 및 이를 이용한 글루탐산 생산방법
JP4623825B2 (ja) 1999-12-16 2011-02-02 協和発酵バイオ株式会社 新規ポリヌクレオチド
BRPI0515035A (pt) * 2004-09-10 2008-07-01 Ajinomoto Kk bactéria corineforme produtora de ácido l-glutámico, método para produzir ácido l-glutámico, gene codificador de alfa-ceto-glutarato desidrogenase mutante, e, alfa-ceto-glutarato desidrogenase mutante
KR100620092B1 (ko) 2004-12-16 2006-09-08 씨제이 주식회사 코리네박테리움 속 세포로부터 유래된 신규한 프로모터서열, 그를 포함하는 발현 카세트 및 벡터, 상기 벡터를포함하는 숙주 세포 및 그를 이용하여 유전자를 발현하는방법
CN103468758B (zh) * 2004-12-28 2015-10-28 味之素株式会社 产生l-谷氨酸的微生物和产生l-谷氨酸的方法
WO2006110083A1 (en) * 2005-04-13 2006-10-19 Astrazeneca Ab A host cell comprising a vector for production of proteins requiring gamma-carboxylation
KR100824457B1 (ko) * 2006-10-16 2008-04-22 씨제이제일제당 (주) 고농도의 글루탐산을 생산하는 미생물 및 이를 이용한글루탐산의 제조 방법
JP2010041920A (ja) * 2006-12-19 2010-02-25 Ajinomoto Co Inc L−アミノ酸の製造法
JP2010130899A (ja) * 2007-03-14 2010-06-17 Ajinomoto Co Inc L−グルタミン酸系アミノ酸生産微生物及びアミノ酸の製造法
KR100937326B1 (ko) * 2007-12-26 2010-01-18 씨제이제일제당 (주) 옥시도리덕테이즈를 코딩하는 유전자가 불활성화된코리네박테리움 속 미생물 및 이를 이용한 5'-이노신산의제조방법
WO2010045381A2 (en) 2008-10-15 2010-04-22 President And Fellows Of Harvard College Antimicrobial agents that target bacterial vkor
EP2655607A4 (de) * 2010-12-21 2014-05-14 Univ North Carolina Verfahren und zusammensetzungen zur herstellung aktiver vitamin-k-abhängiger proteine
JP2016165225A (ja) * 2013-07-09 2016-09-15 味の素株式会社 有用物質の製造方法
KR101632642B1 (ko) 2015-01-29 2016-06-22 씨제이제일제당 주식회사 신규한 프로모터 및 그의 용도
BR112019004161B1 (pt) 2016-08-31 2021-07-27 Cj Cheiljedang Corporation Molécula de ácido nucleico que possui uma atividade promotora, cassete de expressão gênica, vetor recombinante, micro-organismo recombinante do gênero corynebacterium e método de produzir um produto-alvo
KR102730434B1 (ko) * 2021-09-23 2024-11-14 씨제이제일제당 주식회사 고농도 l-글루탐산을 생산하기 위한 균주 및 이를 이용한 l-글루탐산 생산방법

Also Published As

Publication number Publication date
KR20230004002A (ko) 2023-01-06
JP2024521482A (ja) 2024-05-31
TW202302838A (zh) 2023-01-16
AU2022302574B2 (en) 2025-08-14
JP7690070B2 (ja) 2025-06-09
MX2023015552A (es) 2024-01-24
CN118369433A (zh) 2024-07-19
AU2022302574A1 (en) 2024-01-04
ZA202311686B (en) 2025-04-30
TWI819552B (zh) 2023-10-21
EP4349991A1 (de) 2024-04-10
EP4349991A4 (de) 2026-05-06
AR125493A1 (es) 2023-07-19
US20240218381A1 (en) 2024-07-04
KR102665227B1 (ko) 2024-05-10
WO2023277307A1 (ko) 2023-01-05

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