CA3218911A1 - Process for the production of recombinant proteins - Google Patents

Process for the production of recombinant proteins Download PDF

Info

Publication number
CA3218911A1
CA3218911A1 CA3218911A CA3218911A CA3218911A1 CA 3218911 A1 CA3218911 A1 CA 3218911A1 CA 3218911 A CA3218911 A CA 3218911A CA 3218911 A CA3218911 A CA 3218911A CA 3218911 A1 CA3218911 A1 CA 3218911A1
Authority
CA
Canada
Prior art keywords
magnesium
liquid medium
recombinant protein
host cells
process according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3218911A
Other languages
English (en)
French (fr)
Inventor
Geoffrey Norman BROWN
Richard Barry DAVIES
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UCB Biopharma SRL
Original Assignee
UCB Biopharma SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by UCB Biopharma SRL filed Critical UCB Biopharma SRL
Publication of CA3218911A1 publication Critical patent/CA3218911A1/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
CA3218911A 2021-05-10 2022-05-09 Process for the production of recombinant proteins Pending CA3218911A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB2106627.9 2021-05-10
GB202106627 2021-05-10
PCT/EP2022/062469 WO2022238321A1 (en) 2021-05-10 2022-05-09 Process for the production of recombinant proteins

Publications (1)

Publication Number Publication Date
CA3218911A1 true CA3218911A1 (en) 2022-11-17

Family

ID=81975362

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3218911A Pending CA3218911A1 (en) 2021-05-10 2022-05-09 Process for the production of recombinant proteins

Country Status (12)

Country Link
US (1) US20240247050A1 (enExample)
EP (1) EP4337759A1 (enExample)
JP (1) JP2024516892A (enExample)
KR (1) KR20240005876A (enExample)
CN (1) CN117295813A (enExample)
AR (1) AR125806A1 (enExample)
AU (1) AU2022272406A1 (enExample)
BR (1) BR112023022274A2 (enExample)
CA (1) CA3218911A1 (enExample)
IL (1) IL308329A (enExample)
MX (1) MX2023013277A (enExample)
WO (1) WO2022238321A1 (enExample)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013085531A (ja) * 2011-10-20 2013-05-13 Tosoh Corp 遺伝子組換え大腸菌によるタンパク質の製造方法
GB201411320D0 (en) 2014-06-25 2014-08-06 Ucb Biopharma Sprl Antibody construct
CN104928333B (zh) * 2015-07-07 2017-09-22 江南大学 一种敲除glcK促进枯草芽孢杆菌合成乙酰氨基葡萄糖的方法
JP2018011515A (ja) * 2016-07-19 2018-01-25 東ソー株式会社 大腸菌を用いた遺伝子組換えタンパク質の製造方法
US20200207812A1 (en) * 2018-12-07 2020-07-02 Coherus Biosciences, Inc. Methods for producing recombinant proteins
WO2021072182A1 (en) * 2019-10-11 2021-04-15 Coherus Biosciences, Inc. Methods for producing ranibizumab

Also Published As

Publication number Publication date
EP4337759A1 (en) 2024-03-20
AU2022272406A1 (en) 2023-11-02
CN117295813A (zh) 2023-12-26
JP2024516892A (ja) 2024-04-17
IL308329A (en) 2024-01-01
US20240247050A1 (en) 2024-07-25
BR112023022274A2 (pt) 2024-01-30
KR20240005876A (ko) 2024-01-12
AR125806A1 (es) 2023-08-16
MX2023013277A (es) 2023-11-30
WO2022238321A1 (en) 2022-11-17

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