JP2024516892A - 組換えタンパク質の生産方法 - Google Patents

組換えタンパク質の生産方法 Download PDF

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Publication number
JP2024516892A
JP2024516892A JP2023569665A JP2023569665A JP2024516892A JP 2024516892 A JP2024516892 A JP 2024516892A JP 2023569665 A JP2023569665 A JP 2023569665A JP 2023569665 A JP2023569665 A JP 2023569665A JP 2024516892 A JP2024516892 A JP 2024516892A
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JP
Japan
Prior art keywords
magnesium
liquid medium
recombinant protein
bacterial host
total amount
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JP2023569665A
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Japanese (ja)
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JP2024516892A5 (enExample
Inventor
ノーマン ブラウン、ジェフリー
バリー デイビス、リチャード
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ユーシービー バイオファルマ エスアールエル
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Application filed by ユーシービー バイオファルマ エスアールエル filed Critical ユーシービー バイオファルマ エスアールエル
Publication of JP2024516892A publication Critical patent/JP2024516892A/ja
Publication of JP2024516892A5 publication Critical patent/JP2024516892A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
JP2023569665A 2021-05-10 2022-05-09 組換えタンパク質の生産方法 Pending JP2024516892A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB2106627.9 2021-05-10
GB202106627 2021-05-10
PCT/EP2022/062469 WO2022238321A1 (en) 2021-05-10 2022-05-09 Process for the production of recombinant proteins

Publications (2)

Publication Number Publication Date
JP2024516892A true JP2024516892A (ja) 2024-04-17
JP2024516892A5 JP2024516892A5 (enExample) 2025-03-03

Family

ID=81975362

Family Applications (1)

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JP2023569665A Pending JP2024516892A (ja) 2021-05-10 2022-05-09 組換えタンパク質の生産方法

Country Status (12)

Country Link
US (1) US20240247050A1 (enExample)
EP (1) EP4337759A1 (enExample)
JP (1) JP2024516892A (enExample)
KR (1) KR20240005876A (enExample)
CN (1) CN117295813A (enExample)
AR (1) AR125806A1 (enExample)
AU (1) AU2022272406A1 (enExample)
BR (1) BR112023022274A2 (enExample)
CA (1) CA3218911A1 (enExample)
IL (1) IL308329A (enExample)
MX (1) MX2023013277A (enExample)
WO (1) WO2022238321A1 (enExample)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013085531A (ja) * 2011-10-20 2013-05-13 Tosoh Corp 遺伝子組換え大腸菌によるタンパク質の製造方法
JP2018011515A (ja) * 2016-07-19 2018-01-25 東ソー株式会社 大腸菌を用いた遺伝子組換えタンパク質の製造方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201411320D0 (en) 2014-06-25 2014-08-06 Ucb Biopharma Sprl Antibody construct
CN104928333B (zh) * 2015-07-07 2017-09-22 江南大学 一种敲除glcK促进枯草芽孢杆菌合成乙酰氨基葡萄糖的方法
US20200207812A1 (en) * 2018-12-07 2020-07-02 Coherus Biosciences, Inc. Methods for producing recombinant proteins
WO2021072182A1 (en) * 2019-10-11 2021-04-15 Coherus Biosciences, Inc. Methods for producing ranibizumab

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013085531A (ja) * 2011-10-20 2013-05-13 Tosoh Corp 遺伝子組換え大腸菌によるタンパク質の製造方法
JP2018011515A (ja) * 2016-07-19 2018-01-25 東ソー株式会社 大腸菌を用いた遺伝子組換えタンパク質の製造方法

Also Published As

Publication number Publication date
EP4337759A1 (en) 2024-03-20
AU2022272406A1 (en) 2023-11-02
CN117295813A (zh) 2023-12-26
IL308329A (en) 2024-01-01
US20240247050A1 (en) 2024-07-25
BR112023022274A2 (pt) 2024-01-30
KR20240005876A (ko) 2024-01-12
CA3218911A1 (en) 2022-11-17
AR125806A1 (es) 2023-08-16
MX2023013277A (es) 2023-11-30
WO2022238321A1 (en) 2022-11-17

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