CA3201129A1 - Material and method for treating cancer - Google Patents

Material and method for treating cancer

Info

Publication number
CA3201129A1
CA3201129A1 CA3201129A CA3201129A CA3201129A1 CA 3201129 A1 CA3201129 A1 CA 3201129A1 CA 3201129 A CA3201129 A CA 3201129A CA 3201129 A CA3201129 A CA 3201129A CA 3201129 A1 CA3201129 A1 CA 3201129A1
Authority
CA
Canada
Prior art keywords
composition
cancer
component
composition according
mitomycin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3201129A
Other languages
English (en)
French (fr)
Inventor
Yulia HIONIDI
Omer Tsipori
Marina KONORTY
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Urogen Pharma Ltd
Original Assignee
Urogen Pharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Urogen Pharma Ltd filed Critical Urogen Pharma Ltd
Publication of CA3201129A1 publication Critical patent/CA3201129A1/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA3201129A 2020-12-11 2021-12-09 Material and method for treating cancer Pending CA3201129A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063124111P 2020-12-11 2020-12-11
US63/124,111 2020-12-11
PCT/IB2021/061499 WO2022123480A1 (en) 2020-12-11 2021-12-09 Material and method for treating cancer

Publications (1)

Publication Number Publication Date
CA3201129A1 true CA3201129A1 (en) 2022-06-16

Family

ID=78916713

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3201129A Pending CA3201129A1 (en) 2020-12-11 2021-12-09 Material and method for treating cancer

Country Status (6)

Country Link
US (2) US12336979B2 (https=)
EP (1) EP4259093B1 (https=)
JP (1) JP2023553976A (https=)
KR (1) KR20230118632A (https=)
CA (1) CA3201129A1 (https=)
WO (1) WO2022123480A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10471150B2 (en) 2010-01-20 2019-11-12 Urogen Pharma Ltd. Material and method for treating internal cavities
US12336979B2 (en) 2020-12-11 2025-06-24 Urogen Pharma Ltd. Material and method for treating cancer
US20240100019A1 (en) * 2022-09-28 2024-03-28 Urogen Pharma Ltd. Compositions comprising a thermoreversible hydrogel, and having an extended in-use period
EP4713013A1 (en) 2023-05-16 2026-03-25 UroGen Pharma Ltd. Immunomodulating treatments of body cavities
KR20260043121A (ko) 2023-07-25 2026-03-31 우로젠 파마 엘티디. 미토마이신을 함유하는 열 겔화 제약 조성물을 사용한 저등급 중간-위험 비근침습성 방광암의 치료
CN121729785A (zh) 2023-09-06 2026-03-24 株式会社Lg新能源 袋用片材、袋型电池盒以及用于制造电池盒的方法

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0386960A3 (en) 1989-03-07 1991-10-23 American Cyanamid Company Pharmaceutical compositions useful as drug delivery vehicles and/or as wound dressings
US5861174A (en) 1996-07-12 1999-01-19 University Technology Corporation Temperature sensitive gel for sustained delivery of protein drugs
US6286513B1 (en) 1998-10-22 2001-09-11 Jessie L. Au Methods for treating superficial bladder carcinoma
US20040009212A1 (en) 2002-01-30 2004-01-15 Pharma Power Biotec Co. Ltd. Mucoadhesive thermoresponsive medicament-carrier composition
GB0328060D0 (en) 2003-12-04 2004-01-07 Sod Conseils Rech Applic Botulinum toxin treatment
GB0414825D0 (en) 2004-07-02 2004-08-04 Biostatus Ltd Gel formulations and uses thereof
US20090142259A1 (en) 2006-05-12 2009-06-04 Genentech, Inc. Compositions and methods for the diagnosis and treatment of bladder and urinary tract tumors
US9107815B2 (en) 2008-02-22 2015-08-18 Allergan, Inc. Sustained release poloxamer containing pharmaceutical compositions
EP2313122B1 (en) 2008-07-17 2019-03-06 Micell Technologies, Inc. Drug delivery medical device
US10471150B2 (en) 2010-01-20 2019-11-12 Urogen Pharma Ltd. Material and method for treating internal cavities
ES2732150T3 (es) * 2010-01-20 2019-11-20 Urogen Pharma Ltd Material y método para tratar cavidades internas
EP2734187B1 (en) * 2011-07-20 2018-09-05 UroGen Pharma Ltd. Materials and method for treating internal body cavities
US20140142191A1 (en) 2011-07-20 2014-05-22 Theracoat Ltd. Production of thermoreversible hydrogels for therapeutic applications
PT2865391T (pt) * 2013-10-22 2017-12-22 Medac Ges Für Klinische Spezialpräparate Mbh Processo para a produção de uma composição farmacêutica liofilizada com um conteúdo de mitomicina c
US9801854B1 (en) * 2014-01-17 2017-10-31 Urogen Pharma Ltd. Slow release formulations of cell cycle regulators and anti-cancer agents for local treatment of solid cancer
WO2016004213A2 (en) 2014-07-01 2016-01-07 Vicus Therapeutics, Llc Hydrogels for treating and ameliorating cancers and potentiating the immune system and methods of making and using them
US20170128424A1 (en) 2015-11-11 2017-05-11 Qrono, Inc. Sustained release pharmaceutical compositions and methods of use
JP7265989B2 (ja) * 2016-10-25 2023-04-27 ウロゲン ファーマ リミテッド 体腔の免疫調節治療
WO2018169960A1 (en) 2017-03-17 2018-09-20 The Johns Hopkins University Nanoparticle formulations for enhanced drug delivery to the bladder
EP3498270A1 (en) * 2017-10-30 2019-06-19 Urogen Pharma Ltd. Slow release formulations of cell cycle regulators and anti-cancer agents for local treatment of solid cancer
US12336979B2 (en) 2020-12-11 2025-06-24 Urogen Pharma Ltd. Material and method for treating cancer

Also Published As

Publication number Publication date
KR20230118632A (ko) 2023-08-11
JP2023553976A (ja) 2023-12-26
US20240108603A1 (en) 2024-04-04
EP4259093A1 (en) 2023-10-18
EP4259093B1 (en) 2025-08-13
US20220202773A1 (en) 2022-06-30
US12171747B2 (en) 2024-12-24
US12336979B2 (en) 2025-06-24
WO2022123480A1 (en) 2022-06-16

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