CA3201123A1 - Methodes de traitement de troubles psychiatriques par brexpiprazole chez des patients obeses - Google Patents
Methodes de traitement de troubles psychiatriques par brexpiprazole chez des patients obesesInfo
- Publication number
- CA3201123A1 CA3201123A1 CA3201123A CA3201123A CA3201123A1 CA 3201123 A1 CA3201123 A1 CA 3201123A1 CA 3201123 A CA3201123 A CA 3201123A CA 3201123 A CA3201123 A CA 3201123A CA 3201123 A1 CA3201123 A1 CA 3201123A1
- Authority
- CA
- Canada
- Prior art keywords
- brexpiprazole
- dose
- days
- day
- cyp2d6
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La présente divulgation concerne des méthodes de démarrage d'un traitement par brexpiprazole chez des patients atteints de schizophrénie ou d'une dépression majeure. La présente divulgation concerne en outre des posologies modifiées pour les patients obèses et/ou pour les patients qui sont de mauvais métaboliseurs du CYP2D6. Dans des modes de réalisation, les posologies modifiées administrent une dose quotidienne doublée lors du démarrage du traitement.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US17/139,690 | 2020-12-31 | ||
US17/139,690 US20220202810A1 (en) | 2020-12-31 | 2020-12-31 | Methods of treating psychiatric disorders in obese patients with brexpiprazole |
US17/139,627 US11229644B1 (en) | 2020-12-31 | 2020-12-31 | Methods of treating psychiatric disorders in obese patients with brexpiprazole |
US17/139,627 | 2020-12-31 | ||
PCT/US2021/016329 WO2022146462A1 (fr) | 2020-12-31 | 2021-02-03 | Méthodes de traitement de troubles psychiatriques par brexpiprazole chez des patients obèses |
Publications (1)
Publication Number | Publication Date |
---|---|
CA3201123A1 true CA3201123A1 (fr) | 2022-07-07 |
Family
ID=82259620
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA3201123A Pending CA3201123A1 (fr) | 2020-12-31 | 2021-02-03 | Methodes de traitement de troubles psychiatriques par brexpiprazole chez des patients obeses |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP4271381A1 (fr) |
JP (1) | JP2024502431A (fr) |
AU (1) | AU2021412785A1 (fr) |
CA (1) | CA3201123A1 (fr) |
WO (1) | WO2022146462A1 (fr) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11229644B1 (en) | 2020-12-31 | 2022-01-25 | Lake O'hara Llc | Methods of treating psychiatric disorders in obese patients with brexpiprazole |
WO2023141634A2 (fr) * | 2022-01-24 | 2023-07-27 | Lake O'hara Llc | Méthodes de traitement à base de brexpiprazole chez des patients obèses atteints de troubles psychiatriques |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2902781C (fr) * | 2013-02-27 | 2020-12-29 | Mochida Pharmaceutical Co., Ltd. | Nouveau derive de pyrazole |
PL3426250T3 (pl) * | 2017-05-16 | 2022-08-08 | Bow River LLC | Leczenie pacjenta lekiem będącym substratem CYP3A4 przeciwwskazanym do jednoczesnego podawania z silnym inhibitorem CYP3A4 |
WO2020132522A1 (fr) * | 2018-12-21 | 2020-06-25 | The Regents Of The University Of California | Traitement de troubles neurodéveloppementaux |
-
2021
- 2021-02-03 AU AU2021412785A patent/AU2021412785A1/en active Pending
- 2021-02-03 JP JP2023540740A patent/JP2024502431A/ja active Pending
- 2021-02-03 CA CA3201123A patent/CA3201123A1/fr active Pending
- 2021-02-03 WO PCT/US2021/016329 patent/WO2022146462A1/fr active Application Filing
- 2021-02-03 EP EP21916093.4A patent/EP4271381A1/fr active Pending
Also Published As
Publication number | Publication date |
---|---|
WO2022146462A1 (fr) | 2022-07-07 |
EP4271381A1 (fr) | 2023-11-08 |
AU2021412785A1 (en) | 2023-06-22 |
JP2024502431A (ja) | 2024-01-19 |
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