CA3189847A1 - Pharmaceutical composition for prevention and/or treatment of dialysis pruritus containing il-31 antagonist as active ingredient - Google Patents
Pharmaceutical composition for prevention and/or treatment of dialysis pruritus containing il-31 antagonist as active ingredientInfo
- Publication number
- CA3189847A1 CA3189847A1 CA3189847A CA3189847A CA3189847A1 CA 3189847 A1 CA3189847 A1 CA 3189847A1 CA 3189847 A CA3189847 A CA 3189847A CA 3189847 A CA3189847 A CA 3189847A CA 3189847 A1 CA3189847 A1 CA 3189847A1
- Authority
- CA
- Canada
- Prior art keywords
- weeks
- pruritus
- cim331
- antagonist
- administered
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/JP2020/032987 WO2022049614A1 (ja) | 2020-09-01 | 2020-09-01 | Ｉｌ－３１アンタゴニストを有効成分として含有する、透析そう痒症の予防用及び／又は治療用医薬組成物 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3189847A1 true CA3189847A1 (en) | 2022-03-10 |
Family
ID=73741045
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3189847A Pending CA3189847A1 (en) | 2020-09-01 | 2020-09-01 | Pharmaceutical composition for prevention and/or treatment of dialysis pruritus containing il-31 antagonist as active ingredient |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20230391878A1 (OSRAM) |
| EP (1) | EP4209227A4 (OSRAM) |
| JP (2) | JP6799831B1 (OSRAM) |
| KR (2) | KR102269716B1 (OSRAM) |
| CN (1) | CN116096411A (OSRAM) |
| AU (1) | AU2020466800A1 (OSRAM) |
| CA (1) | CA3189847A1 (OSRAM) |
| IL (1) | IL300694A (OSRAM) |
| MX (1) | MX2023002482A (OSRAM) |
| WO (1) | WO2022049614A1 (OSRAM) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW202515609A (zh) | 2015-04-14 | 2025-04-16 | 日商中外製藥股份有限公司 | 含有il-31拮抗劑作為有效成分之異位性皮膚炎的預防用及/或治療用醫藥組合物 |
| KR102886159B1 (ko) | 2015-04-14 | 2025-11-13 | 추가이 세이야쿠 가부시키가이샤 | Il-31 안타고니스트를 유효 성분으로서 함유하는 아토피성 피부염의 예방용 및/또는 치료용 의약 조성물 |
| WO2018156180A1 (en) | 2017-02-24 | 2018-08-30 | Kindred Biosciences, Inc. | Anti-il31 antibodies for veterinary use |
| MX2022005654A (es) | 2019-11-20 | 2022-06-22 | Chugai Pharmaceutical Co Ltd | Preparacion que contiene anticuerpo. |
| CN120441701A (zh) * | 2024-02-07 | 2025-08-08 | 武汉人福创新药物研发中心有限公司 | 一种靶向il-31ra的抗体或其抗原结合片段及其应用 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2707189B1 (fr) | 1993-07-09 | 1995-10-13 | Gradient Ass | Procédé de traitement de résidus de combustion et installation de mise en Óoeuvre dudit procédé. |
| PT1071700E (pt) | 1998-04-20 | 2010-04-23 | Glycart Biotechnology Ag | Modificação por glicosilação de anticorpos para melhorar a citotoxicidade celular dependente de anticorpos |
| WO2000061739A1 (fr) | 1999-04-09 | 2000-10-19 | Kyowa Hakko Kogyo Co., Ltd. | Methode de regulation de l'activite d'une molecule immunologiquement fonctionnelle |
| EP2325316B8 (en) | 1999-06-02 | 2017-04-19 | Chugai Seiyaku Kabushiki Kaisha | Novel hemopoietin receptor protein, NR10 |
| JP5291279B2 (ja) | 2000-09-08 | 2013-09-18 | ウニヴェルジテート・チューリッヒ | 反復モジュールを含む反復タンパク質の集合体 |
| WO2002032925A2 (en) | 2000-10-16 | 2002-04-25 | Phylos, Inc. | Protein scaffolds for antibody mimics and other binding proteins |
| US20030157561A1 (en) | 2001-11-19 | 2003-08-21 | Kolkman Joost A. | Combinatorial libraries of monomer domains |
| JP2002338476A (ja) * | 2001-05-21 | 2002-11-27 | Health Factor Kenkyusho:Kk | 腎透析に伴う痒みの予防治療剤 |
| PT1576112E (pt) | 2002-01-18 | 2012-05-25 | Zymogenetics Inc | Multímeros de receptor de citocina zcytor17 |
| WO2005079566A2 (en) | 2004-02-12 | 2005-09-01 | Lexicon Genetics Incorporated | Gene disruptions, compositions and methods relating thereto |
| EP1671642A1 (en) | 2004-12-15 | 2006-06-21 | Universite D'angers | Compositions comprising (ant)agonists of oncostatin M (OSM), IL-31 and IFN-gamma for modulating keratinocyte migration and functions via a receptor containing OSMRbeta as a subunit, and applications thereof. |
| AU2006214404B2 (en) | 2005-02-14 | 2012-03-08 | Bristol-Myers Squibb Company | Methods of treating skin disorders using an IL-31RA antagonist |
| JP2008530137A (ja) | 2005-02-14 | 2008-08-07 | ザイモジェネティクス，インコーポレイティド | 皮膚リンパ球抗原陽性細胞により仲介される疾患を治療するための方法 |
| US7531637B2 (en) | 2005-05-06 | 2009-05-12 | Zymogenetics, Inc. | IL-31 monoclonal antibodies |
| CN101589060A (zh) * | 2006-01-10 | 2009-11-25 | 津莫吉尼蒂克斯公司 | 使用il-31拮抗剂在神经元性组织中治疗疼痛和炎症的方法 |
| JP2009526756A (ja) | 2006-01-10 | 2009-07-23 | ザイモジェネティクス， インコーポレイテッド | Ｉｌ−３１ｒａアンタゴニストおよびｏｓｍｒｂアンタゴニストを用いて神経組織における疼痛および炎症を治療する方法 |
| PT2047863E (pt) | 2006-06-08 | 2013-10-21 | Chugai Pharmaceutical Co Ltd | Prevenção ou tratamento para doença inflamatória |
| SI2594586T1 (sl) | 2006-09-01 | 2014-11-28 | Zymogenetics, Inc. | IL-31 monoklonska protitelesa in metode uporabe |
| BRPI0821145B8 (pt) | 2007-12-05 | 2021-05-25 | Chugai Pharmaceutical Co Ltd | uso de um anticorpo anti-nr10 como agente preventivo ou terapêutico para prurido |
| WO2009072604A1 (ja) | 2007-12-05 | 2009-06-11 | Chugai Seiyaku Kabushiki Kaisha | 抗nr10抗体、およびその利用 |
| WO2009071696A2 (en) | 2007-12-07 | 2009-06-11 | Zymogenetics, Inc. | Humanized antibody molecules specific for il-31 |
| JP2010210772A (ja) | 2009-03-13 | 2010-09-24 | Dainippon Screen Mfg Co Ltd | 液晶表示装置の製造方法 |
| WO2014208645A1 (ja) * | 2013-06-28 | 2014-12-31 | 中外製薬株式会社 | そう痒を伴う疾患に罹患した患者のｉｌ－３１アンタゴニストによる治療に対する応答を予測する方法 |
| JP6359014B2 (ja) * | 2013-08-21 | 2018-07-18 | 久光製薬株式会社 | 貼付剤 |
| US20190135804A1 (en) * | 2017-11-03 | 2019-05-09 | The United States Of America,As Represented By The Secretary,Department Of Health And Human Services | Compositions and methods for the inhibition of pruritus |
| KR102156932B1 (ko) * | 2017-11-23 | 2020-09-17 | 주식회사 헬릭스미스 | 천연추출물을 포함하는 소양증의 예방 또는 치료용 조성물 |
| KR20250127348A (ko) * | 2018-04-25 | 2025-08-26 | 키닉사 파마슈티컬스, 리미티드 | 항-OSMRß 항체 전달에 의한 피부 질환 또는 장애 치료 |
-
2020
- 2020-09-01 IL IL300694A patent/IL300694A/en unknown
- 2020-09-01 KR KR1020207030800A patent/KR102269716B1/ko active Active
- 2020-09-01 EP EP20952354.7A patent/EP4209227A4/en active Pending
- 2020-09-01 MX MX2023002482A patent/MX2023002482A/es unknown
- 2020-09-01 CA CA3189847A patent/CA3189847A1/en active Pending
- 2020-09-01 CN CN202080103639.6A patent/CN116096411A/zh active Pending
- 2020-09-01 JP JP2020551453A patent/JP6799831B1/ja active Active
- 2020-09-01 KR KR1020217018823A patent/KR102800698B1/ko active Active
- 2020-09-01 WO PCT/JP2020/032987 patent/WO2022049614A1/ja not_active Ceased
- 2020-09-01 AU AU2020466800A patent/AU2020466800A1/en active Pending
- 2020-09-01 US US18/023,246 patent/US20230391878A1/en active Pending
- 2020-11-11 JP JP2020187708A patent/JP7548784B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2022041802A (ja) | 2022-03-11 |
| JPWO2022049614A1 (OSRAM) | 2022-03-10 |
| IL300694A (en) | 2023-04-01 |
| KR102800698B1 (ko) | 2025-04-24 |
| KR20230048233A (ko) | 2023-04-11 |
| AU2020466800A1 (en) | 2023-03-23 |
| EP4209227A4 (en) | 2024-05-29 |
| JP7548784B2 (ja) | 2024-09-10 |
| US20230391878A1 (en) | 2023-12-07 |
| CN116096411A (zh) | 2023-05-09 |
| JP6799831B1 (ja) | 2020-12-16 |
| MX2023002482A (es) | 2023-03-08 |
| KR102269716B1 (ko) | 2021-06-28 |
| EP4209227A1 (en) | 2023-07-12 |
| WO2022049614A1 (ja) | 2022-03-10 |
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