CA3179701A1 - Initiateurs reutilisables pour la synthese d'acides nucleiques - Google Patents
Initiateurs reutilisables pour la synthese d'acides nucleiquesInfo
- Publication number
- CA3179701A1 CA3179701A1 CA3179701A CA3179701A CA3179701A1 CA 3179701 A1 CA3179701 A1 CA 3179701A1 CA 3179701 A CA3179701 A CA 3179701A CA 3179701 A CA3179701 A CA 3179701A CA 3179701 A1 CA3179701 A1 CA 3179701A1
- Authority
- CA
- Canada
- Prior art keywords
- modified
- nucleotide
- group
- exo
- deoxyguanosine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/07—Nucleotidyltransferases (2.7.7)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Saccharide Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
L'invention concerne des procédés améliorés de synthèse de polynucléotides, tels que l'ADN et l'ARN, à l'aide d'initiateurs renouvelables couplés à un support solide. Au moyen des procédés de l'invention, des séquences spécifiques de polynucléotides peuvent être synthétisées de novo, base par base, dans un environnement aqueux, sans l'utilisation d'un modèle d'acide nucléique.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16/841,214 US11384377B2 (en) | 2013-04-02 | 2020-04-06 | Reusable initiators for synthesizing nucleic acids |
US16/841,214 | 2020-04-06 | ||
PCT/US2021/025918 WO2021207158A1 (fr) | 2020-04-06 | 2021-04-06 | Initiateurs réutilisables pour la synthèse d'acides nucléiques |
Publications (1)
Publication Number | Publication Date |
---|---|
CA3179701A1 true CA3179701A1 (fr) | 2021-10-14 |
Family
ID=78023444
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA3179701A Pending CA3179701A1 (fr) | 2020-04-06 | 2021-04-06 | Initiateurs reutilisables pour la synthese d'acides nucleiques |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP4133070A1 (fr) |
JP (1) | JP2023521704A (fr) |
CN (1) | CN116096882A (fr) |
AU (1) | AU2021252542A1 (fr) |
CA (1) | CA3179701A1 (fr) |
WO (1) | WO2021207158A1 (fr) |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5872244A (en) * | 1994-09-02 | 1999-02-16 | Andrew C. Hiatt | 3' protected nucleotides for enzyme catalyzed template-independent creation of phosphodiester bonds |
US8808989B1 (en) * | 2013-04-02 | 2014-08-19 | Molecular Assemblies, Inc. | Methods and apparatus for synthesizing nucleic acids |
-
2021
- 2021-04-06 JP JP2022560973A patent/JP2023521704A/ja active Pending
- 2021-04-06 CN CN202180039885.4A patent/CN116096882A/zh active Pending
- 2021-04-06 AU AU2021252542A patent/AU2021252542A1/en active Pending
- 2021-04-06 CA CA3179701A patent/CA3179701A1/fr active Pending
- 2021-04-06 WO PCT/US2021/025918 patent/WO2021207158A1/fr unknown
- 2021-04-06 EP EP21785385.2A patent/EP4133070A1/fr active Pending
Also Published As
Publication number | Publication date |
---|---|
EP4133070A1 (fr) | 2023-02-15 |
AU2021252542A1 (en) | 2022-11-10 |
CN116096882A (zh) | 2023-05-09 |
WO2021207158A1 (fr) | 2021-10-14 |
JP2023521704A (ja) | 2023-05-25 |
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