CA3174980A1 - Nouveaux agents antipaludiques - Google Patents
Nouveaux agents antipaludiquesInfo
- Publication number
- CA3174980A1 CA3174980A1 CA3174980A CA3174980A CA3174980A1 CA 3174980 A1 CA3174980 A1 CA 3174980A1 CA 3174980 A CA3174980 A CA 3174980A CA 3174980 A CA3174980 A CA 3174980A CA 3174980 A1 CA3174980 A1 CA 3174980A1
- Authority
- CA
- Canada
- Prior art keywords
- oxo
- trifluoroethyl
- iii
- formula
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La présente invention concerne de nouveaux dérivés dans la fabrication d'un médicament pour la prévention ou le traitement du paludisme. En particulier, la présente invention concerne des dérivés de dihydroisoquinoléine utiles pour la préparation d'une formulation pharmaceutique pour l'inhibition de la prolifération des parasites du paludisme.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US202063007385P | 2020-04-09 | 2020-04-09 | |
EP20169099.7 | 2020-04-09 | ||
US63/007,385 | 2020-04-09 | ||
EP20169099.7A EP3892332A1 (fr) | 2020-04-09 | 2020-04-09 | Nouveaux agents anti-paludiques |
PCT/EP2021/059196 WO2021204952A1 (fr) | 2020-04-09 | 2021-04-08 | Nouveaux agents antipaludiques |
Publications (1)
Publication Number | Publication Date |
---|---|
CA3174980A1 true CA3174980A1 (fr) | 2021-10-14 |
Family
ID=70285536
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA3174980A Pending CA3174980A1 (fr) | 2020-04-09 | 2021-04-08 | Nouveaux agents antipaludiques |
Country Status (7)
Country | Link |
---|---|
US (1) | US20230174503A1 (fr) |
EP (2) | EP3892332A1 (fr) |
JP (1) | JP2023520816A (fr) |
CN (1) | CN115380027A (fr) |
BR (1) | BR112022019710A2 (fr) |
CA (1) | CA3174980A1 (fr) |
WO (1) | WO2021204952A1 (fr) |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR112014004437B1 (pt) | 2011-08-25 | 2021-12-14 | St. Jude Children's Research Hospital | Composto, uso de um composto, composição farmacêutica, formulação farmacêutica, processo para preparação de um composto, e intermediário |
GB201206280D0 (en) * | 2012-04-10 | 2012-05-23 | Univ Dundee | Anti-malarial agents |
CN105294561B (zh) * | 2015-11-27 | 2018-03-30 | 中国药科大学 | 一种异喹啉及其制备方法和应用 |
-
2020
- 2020-04-09 EP EP20169099.7A patent/EP3892332A1/fr not_active Withdrawn
-
2021
- 2021-04-08 EP EP21717085.1A patent/EP4132918A1/fr active Pending
- 2021-04-08 WO PCT/EP2021/059196 patent/WO2021204952A1/fr active Application Filing
- 2021-04-08 CN CN202180027409.0A patent/CN115380027A/zh active Pending
- 2021-04-08 BR BR112022019710A patent/BR112022019710A2/pt unknown
- 2021-04-08 US US17/917,593 patent/US20230174503A1/en active Pending
- 2021-04-08 CA CA3174980A patent/CA3174980A1/fr active Pending
- 2021-04-08 JP JP2022562063A patent/JP2023520816A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
WO2021204952A1 (fr) | 2021-10-14 |
CN115380027A (zh) | 2022-11-22 |
BR112022019710A2 (pt) | 2022-11-16 |
JP2023520816A (ja) | 2023-05-19 |
US20230174503A1 (en) | 2023-06-08 |
EP3892332A1 (fr) | 2021-10-13 |
EP4132918A1 (fr) | 2023-02-15 |
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