CA3166637A1 - Methods for treating inflammatory bowel diseases with .alpha.4.beta.7 integrin antagonists - Google Patents
Methods for treating inflammatory bowel diseases with .alpha.4.beta.7 integrin antagonistsInfo
- Publication number
- CA3166637A1 CA3166637A1 CA3166637A CA3166637A CA3166637A1 CA 3166637 A1 CA3166637 A1 CA 3166637A1 CA 3166637 A CA3166637 A CA 3166637A CA 3166637 A CA3166637 A CA 3166637A CA 3166637 A1 CA3166637 A1 CA 3166637A1
- Authority
- CA
- Canada
- Prior art keywords
- peptides
- pen
- lys
- glu
- phe
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062959854P | 2020-01-10 | 2020-01-10 | |
| US62/959,854 | 2020-01-10 | ||
| PCT/US2021/012842 WO2021142373A1 (en) | 2020-01-10 | 2021-01-08 | METHODS FOR TREATING INFLAMMATORY BOWEL DISEASES WITH α4β7 INTEGRIN ANTAGONISTS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3166637A1 true CA3166637A1 (en) | 2021-07-15 |
Family
ID=76788328
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3166637A Pending CA3166637A1 (en) | 2020-01-10 | 2021-01-08 | Methods for treating inflammatory bowel diseases with .alpha.4.beta.7 integrin antagonists |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20230063321A1 (enExample) |
| EP (1) | EP4093421A4 (enExample) |
| JP (2) | JP7744910B2 (enExample) |
| KR (1) | KR20220125268A (enExample) |
| AU (1) | AU2021205415B2 (enExample) |
| BR (1) | BR112022013628A2 (enExample) |
| CA (1) | CA3166637A1 (enExample) |
| IL (1) | IL294580A (enExample) |
| MX (1) | MX2022008486A (enExample) |
| PH (1) | PH12022551651A1 (enExample) |
| WO (1) | WO2021142373A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4091624A1 (en) | 2013-03-15 | 2022-11-23 | Protagonist Therapeutics, Inc. | Hepcidin analogues and uses thereof |
| CA2949215C (en) | 2014-05-16 | 2023-03-14 | Protagonist Therapeutics, Inc. | .alpha.4.beta.7 integrin thioether peptide antagonists |
| SG10201810154WA (en) | 2014-07-17 | 2018-12-28 | Protagonist Therapeutics Inc | Oral peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory bowel diseases |
| WO2018022937A1 (en) | 2016-07-27 | 2018-02-01 | Protagonist Therapeutics, Inc. | Peptide inhibitors of interleukin-23 and their use to treat inflammatory diseases |
| WO2019157268A1 (en) | 2018-02-08 | 2019-08-15 | Protagonist Therapeutics, Inc. | Conjugated hepcidin mimetics |
| CA3104418A1 (en) | 2018-07-12 | 2020-01-16 | Protagonist Therapeutics, Inc. | Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases |
| MX2022008740A (es) | 2020-01-15 | 2022-09-23 | Janssen Biotech Inc | Peptidos inhibidores del receptor de interleucina-23 y su uso para tratar enfermedades inflamatorias. |
| SMT202500254T1 (it) | 2020-01-15 | 2025-09-12 | Janssen Biotech Inc | Inibitori peptidici del recettore dell'interleuchina-23 e loro uso per trattare malattie infiammatorie |
| AU2021383828A1 (en) | 2020-11-20 | 2023-07-06 | Janssen Pharmaceutica Nv | Compositions of peptide inhibitors of interleukin-23 receptor |
| KR20240034224A (ko) | 2021-07-14 | 2024-03-13 | 얀센 바이오테크 인코포레이티드 | 인터류킨-23 수용체의 지질화된 펩티드 억제제 |
| KR20250084325A (ko) * | 2023-12-01 | 2025-06-11 | 주식회사 쓰리빅스 | 염증성 장질환 예방 또는 치료용 약학 조성물 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2013011130A (es) * | 2011-03-31 | 2013-10-30 | Genentech Inc | Metodos de administracion de antagonistas de integrina beta7. |
| WO2013078375A2 (en) * | 2011-11-23 | 2013-05-30 | Amgen Inc. | Administration of alpha4beta7 hetero-dimer-specific antibody |
| US9273093B2 (en) * | 2012-10-11 | 2016-03-01 | Protagonist Therapeutics, Inc. | α4β7 peptide dimer antagonists |
| CA2949215C (en) * | 2014-05-16 | 2023-03-14 | Protagonist Therapeutics, Inc. | .alpha.4.beta.7 integrin thioether peptide antagonists |
| JP2017535527A (ja) * | 2014-10-01 | 2017-11-30 | プロタゴニスト セラピューティクス， インコーポレイテッド | 新規のα４β７ペプチド単量体及び二量体拮抗薬 |
| KR20200015540A (ko) * | 2017-05-10 | 2020-02-12 | 인사이클 세라퓨틱스, 인코포레이티드 | α4β7 인테그린을 타겟팅하는 호모데틱 사이클릭 펩타이드 |
-
2021
- 2021-01-08 EP EP21738981.6A patent/EP4093421A4/en active Pending
- 2021-01-08 JP JP2022542360A patent/JP7744910B2/ja active Active
- 2021-01-08 BR BR112022013628A patent/BR112022013628A2/pt not_active Application Discontinuation
- 2021-01-08 MX MX2022008486A patent/MX2022008486A/es unknown
- 2021-01-08 CA CA3166637A patent/CA3166637A1/en active Pending
- 2021-01-08 WO PCT/US2021/012842 patent/WO2021142373A1/en not_active Ceased
- 2021-01-08 PH PH1/2022/551651A patent/PH12022551651A1/en unknown
- 2021-01-08 AU AU2021205415A patent/AU2021205415B2/en active Active
- 2021-01-08 US US17/788,179 patent/US20230063321A1/en active Pending
- 2021-01-08 KR KR1020227025943A patent/KR20220125268A/ko not_active Withdrawn
-
2022
- 2022-07-07 IL IL294580A patent/IL294580A/en unknown
-
2025
- 2025-09-12 JP JP2025151922A patent/JP2025186365A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2021142373A1 (en) | 2021-07-15 |
| JP2023509790A (ja) | 2023-03-09 |
| JP7744910B2 (ja) | 2025-09-26 |
| AU2021205415A8 (en) | 2023-08-10 |
| IL294580A (en) | 2022-09-01 |
| US20230063321A1 (en) | 2023-03-02 |
| AU2021205415B2 (en) | 2026-06-04 |
| KR20220125268A (ko) | 2022-09-14 |
| PH12022551651A1 (en) | 2023-11-20 |
| EP4093421A1 (en) | 2022-11-30 |
| MX2022008486A (es) | 2022-10-13 |
| CN115038457A (zh) | 2022-09-09 |
| BR112022013628A2 (pt) | 2022-11-22 |
| JP2025186365A (ja) | 2025-12-23 |
| EP4093421A4 (en) | 2024-01-10 |
| AU2021205415A1 (en) | 2022-07-21 |
Similar Documents
| Publication | Publication Date | Title |
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| CA2323071C (en) | Molecules that home to various selected organs or tissues | |
| JP7209364B2 (ja) | 内在化ペプチド連結薬剤と抗炎症剤との共投与 | |
| AU2002362710B2 (en) | Use of thymulin-like peptides for making pain-relieving medicines | |
| JP2020505352A (ja) | インターロイキン−２３受容体のペプチド阻害剤および炎症性疾患を治療するためのそれらの使用 | |
| JP2005537245A5 (ja) | プロテイナーゼ活性化レセプターのアンタゴニストを含む組成物および方法 | |
| CN105579054A (zh) | 预防或治疗左心室重塑的方法 | |
| EP4397678A2 (en) | Methods and compositions for treating liver disease | |
| US20230382998A1 (en) | METHODS FOR TREATING INFLAMMATORY BOWEL DISEASES WITH a4B7 INTEGRIN ANTAGONISTS | |
| EP4013442A1 (en) | Treatment | |
| WO2020000063A1 (en) | Rheumatoid arthritis treatment | |
| HK1235801B (en) | Alpha4beta7 integrin thioether peptide antagonists |
Legal Events
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| D15 | Examination report completed |
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