CA3149947A1 - Expandable hemostat composed of oxidized cellulose - Google Patents

Expandable hemostat composed of oxidized cellulose Download PDF

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Publication number
CA3149947A1
CA3149947A1 CA3149947A CA3149947A CA3149947A1 CA 3149947 A1 CA3149947 A1 CA 3149947A1 CA 3149947 A CA3149947 A CA 3149947A CA 3149947 A CA3149947 A CA 3149947A CA 3149947 A1 CA3149947 A1 CA 3149947A1
Authority
CA
Canada
Prior art keywords
matrix
orc
expandable
aqueous solution
expansion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3149947A
Other languages
English (en)
French (fr)
Inventor
Erez Ilan
Omri FAINGOLD
Tamar AEURBACH-NEVO
Tali NEGREANU-GILBOA
Hadas ALPERIN
Allen Wang
Dwayne Looney
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ethicon Inc
Original Assignee
Ethicon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ethicon Inc filed Critical Ethicon Inc
Publication of CA3149947A1 publication Critical patent/CA3149947A1/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/28—Polysaccharides or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/425—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/44—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/64—Use of materials characterised by their function or physical properties specially adapted to be resorbable inside the body
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L1/00—Compositions of cellulose, modified cellulose or cellulose derivatives
    • C08L1/02—Cellulose; Modified cellulose
    • C08L1/04—Oxycellulose; Hydrocellulose, e.g. microcrystalline cellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/23—Carbohydrates
    • A61L2300/232—Monosaccharides, disaccharides, polysaccharides, lipopolysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602—Type of release, e.g. controlled, sustained, slow
    • A61L2300/604—Biodegradation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/04—Materials for stopping bleeding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
CA3149947A 2019-08-07 2020-08-03 Expandable hemostat composed of oxidized cellulose Pending CA3149947A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962883764P 2019-08-07 2019-08-07
IL268572A IL268572A (en) 2019-08-07 2019-08-07 An expandable hemostatic composed of oxidized cellulose
IL268572 2019-08-07
US62/883,764 2019-08-07
PCT/IB2020/057322 WO2021024159A1 (en) 2019-08-07 2020-08-03 Expandable hemostat composed of oxidized cellulose

Publications (1)

Publication Number Publication Date
CA3149947A1 true CA3149947A1 (en) 2021-02-11

Family

ID=68069448

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3149947A Pending CA3149947A1 (en) 2019-08-07 2020-08-03 Expandable hemostat composed of oxidized cellulose

Country Status (10)

Country Link
US (1) US20210038757A1 (zh)
EP (1) EP4010038A1 (zh)
JP (1) JP2022550247A (zh)
KR (1) KR20220044792A (zh)
CN (1) CN114340685B (zh)
AU (1) AU2020325760A1 (zh)
BR (1) BR112022002185A2 (zh)
CA (1) CA3149947A1 (zh)
IL (2) IL268572A (zh)
WO (1) WO2021024159A1 (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11654057B2 (en) 2020-04-09 2023-05-23 Bio 54, Llc Devices for bleeding reduction and methods of making and using the same
KR102458897B1 (ko) * 2022-02-21 2022-10-27 대가파우더시스템 주식회사 지혈제가 내재된 지혈 유닛
US20240148933A1 (en) 2022-11-08 2024-05-09 Ethicon, Inc. Expandable hemostatic tablets comprising oxidized regenerated cellulose

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3364200A (en) 1960-03-28 1968-01-16 Johnson & Johnson Oxidized cellulose product and method for preparing the same
US5180398A (en) 1990-12-20 1993-01-19 Johnson & Johnson Medical, Inc. Cellulose oxidation by a perfluorinated hydrocarbon solution of nitrogen dioxide
US8083768B2 (en) 2000-12-14 2011-12-27 Ensure Medical, Inc. Vascular plug having composite construction
US7279177B2 (en) * 2002-06-28 2007-10-09 Ethicon, Inc. Hemostatic wound dressings and methods of making same
US20040120993A1 (en) * 2002-12-20 2004-06-24 Guanghui Zhang Hemostatic wound dressing and fabric and methods of making and using same
US7019191B2 (en) * 2003-03-25 2006-03-28 Ethicon, Inc. Hemostatic wound dressings and methods of making same
US20040265371A1 (en) 2003-06-25 2004-12-30 Looney Dwayne Lee Hemostatic devices and methods of making same
US20050287215A1 (en) * 2004-06-29 2005-12-29 Looney Dwayne L Hemostatic compositions and devices
US20060078589A1 (en) 2004-10-12 2006-04-13 Jensen Steven D Device for treating oral wound gaps
US20070014862A1 (en) * 2004-10-12 2007-01-18 Cornelis Pameijer Device for treating wound gaps
EP2345430B1 (en) 2004-10-20 2015-11-25 Ethicon, Inc. A reinforced absorbable multilayered fabric for use in medical devices and method of manufacture
US20080027365A1 (en) * 2006-06-01 2008-01-31 Huey Raymond J Hemostatic device with oxidized cellulose pad
US8828050B2 (en) 2009-05-04 2014-09-09 Oregon Biomedical Engineering Institute Hemorrhage control devices and methods
US8518064B2 (en) 2009-12-17 2013-08-27 Cook Medical Technologies Llc Method for anchoring occlusion plug
US9623223B2 (en) 2011-02-16 2017-04-18 Revmedx, Inc. Wound dressings comprising a plurality of liquid-expandable articles
KR101878774B1 (ko) * 2015-04-15 2018-07-17 주식회사 삼양바이오팜 다기능성 지혈제 및 그 제조 방법
ES2952093T3 (es) * 2015-08-14 2023-10-27 Ethicon Inc Tratamiento contra el cáncer mejorado con doxorrubicina
JP6926101B2 (ja) * 2015-11-06 2021-08-25 エシコン・インコーポレイテッドＥｔｈｉｃｏｎ， Ｉｎｃ． 圧密止血セルロース系凝集体

Also Published As

Publication number Publication date
IL290369A (en) 2022-04-01
CN114340685A (zh) 2022-04-12
US20210038757A1 (en) 2021-02-11
BR112022002185A2 (pt) 2022-05-03
JP2022550247A (ja) 2022-12-01
AU2020325760A1 (en) 2022-03-24
WO2021024159A1 (en) 2021-02-11
KR20220044792A (ko) 2022-04-11
CN114340685B (zh) 2024-01-02
EP4010038A1 (en) 2022-06-15
IL268572A (en) 2019-09-26

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