CA3142101A1 - Methods and compositions for generating nitric oxide and uses thereof - Google Patents

Methods and compositions for generating nitric oxide and uses thereof

Info

Publication number
CA3142101A1
CA3142101A1 CA3142101A CA3142101A CA3142101A1 CA 3142101 A1 CA3142101 A1 CA 3142101A1 CA 3142101 A CA3142101 A CA 3142101A CA 3142101 A CA3142101 A CA 3142101A CA 3142101 A1 CA3142101 A1 CA 3142101A1
Authority
CA
Canada
Prior art keywords
acid
combination
nitrite
composition
kit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3142101A
Other languages
English (en)
French (fr)
Inventor
Hugh Semple Munro
Christopher Barry Wood
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Thirty Holdings Ltd
Original Assignee
Thirty Holdings Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB1907969.8A external-priority patent/GB201907969D0/en
Priority claimed from GB201915280A external-priority patent/GB201915280D0/en
Priority claimed from GBGB2005980.4A external-priority patent/GB202005980D0/en
Application filed by Thirty Holdings Ltd filed Critical Thirty Holdings Ltd
Publication of CA3142101A1 publication Critical patent/CA3142101A1/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B21/00—Nitrogen; Compounds thereof
    • C01B21/20—Nitrogen oxides; Oxyacids of nitrogen; Salts thereof
    • C01B21/24—Nitric oxide (NO)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Communicable Diseases (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA3142101A 2019-06-04 2020-06-02 Methods and compositions for generating nitric oxide and uses thereof Pending CA3142101A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GB1907969.8 2019-06-04
GBGB1907969.8A GB201907969D0 (en) 2019-06-04 2019-06-04 Methods and compositions for generating nitric oxide and uses thereof
GB1915280.0 2019-10-22
GB201915280A GB201915280D0 (en) 2019-10-22 2019-10-22 Methods and compositions for generating nitric oxide and uses thereof
GBGB2005980.4A GB202005980D0 (en) 2020-04-23 2020-04-23 Methods and compositions for generating nitric oxide and uses thereof
GB2005980.4 2020-04-23
PCT/GB2020/051328 WO2020245573A1 (en) 2019-06-04 2020-06-02 Methods and compositions for generating nitric oxide and uses thereof

Publications (1)

Publication Number Publication Date
CA3142101A1 true CA3142101A1 (en) 2020-12-10

Family

ID=71083655

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3142101A Pending CA3142101A1 (en) 2019-06-04 2020-06-02 Methods and compositions for generating nitric oxide and uses thereof

Country Status (9)

Country Link
US (1) US20220370493A1 (enExample)
EP (1) EP3980373A1 (enExample)
JP (1) JP2023510661A (enExample)
CN (1) CN114206325B (enExample)
AU (1) AU2020286677B2 (enExample)
BR (1) BR112021023832A8 (enExample)
CA (1) CA3142101A1 (enExample)
GB (1) GB2599576B (enExample)
WO (1) WO2020245573A1 (enExample)

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EP4138795A1 (en) * 2020-04-23 2023-03-01 Thirty Respiratory Limited Nitric oxide or nitric oxide releasing compositions for use in treating sars-cov and sars-cov-2
JP7509380B2 (ja) * 2020-06-19 2024-07-02 株式会社ダイイチ ウイルス不活化製剤
KR20230145103A (ko) * 2021-02-11 2023-10-17 써모라이프 인터내셔널, 엘엘씨 산화질소 기체의 투여 방법
GB202215758D0 (en) * 2022-10-25 2022-12-07 Thirty Holdings Ltd Implantable medical devices
GB202302118D0 (en) * 2023-02-14 2023-03-29 Thirty Therapeutics Ltd Compositions, kits and combinations
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Also Published As

Publication number Publication date
AU2020286677B2 (en) 2025-12-04
WO2020245573A1 (en) 2020-12-10
JP2023510661A (ja) 2023-03-15
GB2599576A (en) 2022-04-06
EP3980373A1 (en) 2022-04-13
CN114206325A (zh) 2022-03-18
AU2020286677A1 (en) 2021-12-09
BR112021023832A2 (pt) 2022-01-04
BR112021023832A8 (pt) 2023-02-28
CN114206325B (zh) 2024-10-29
GB2599576B (en) 2023-09-13
US20220370493A1 (en) 2022-11-24

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