CA3138644A1 - Halogenated antimicrobial peptoids - Google Patents

Halogenated antimicrobial peptoids Download PDF

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Publication number
CA3138644A1
CA3138644A1 CA3138644A CA3138644A CA3138644A1 CA 3138644 A1 CA3138644 A1 CA 3138644A1 CA 3138644 A CA3138644 A CA 3138644A CA 3138644 A CA3138644 A CA 3138644A CA 3138644 A1 CA3138644 A1 CA 3138644A1
Authority
CA
Canada
Prior art keywords
compound
halogen
residues
aryl moiety
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3138644A
Other languages
English (en)
French (fr)
Inventor
Natalia Molchanova
Havard JENSSEN
Annelise Barron
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Maxwell Biosciences Inc
Original Assignee
Maxwell Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Maxwell Biosciences Inc filed Critical Maxwell Biosciences Inc
Publication of CA3138644A1 publication Critical patent/CA3138644A1/en
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CA3138644A 2019-04-30 2020-04-30 Halogenated antimicrobial peptoids Pending CA3138644A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962841227P 2019-04-30 2019-04-30
US62/841,227 2019-04-30
PCT/US2020/030890 WO2020223581A1 (en) 2019-04-30 2020-04-30 Halogenated antimicrobial peptoids

Publications (1)

Publication Number Publication Date
CA3138644A1 true CA3138644A1 (en) 2020-11-05

Family

ID=73029339

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3138644A Pending CA3138644A1 (en) 2019-04-30 2020-04-30 Halogenated antimicrobial peptoids

Country Status (5)

Country Link
US (1) US20220213144A1 (https=)
EP (1) EP3962925A4 (https=)
JP (2) JP7745323B2 (https=)
CA (1) CA3138644A1 (https=)
WO (1) WO2020223581A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2022002696A (es) * 2019-09-03 2022-07-21 Maxwell Biosciences Inc Composiciones de peptoides antivirales.
CN112698030B (zh) * 2020-12-10 2022-02-01 丹娜(天津)生物科技股份有限公司 一种基于酶联免疫法检测新型冠状病毒抗体的试剂盒
EP4047012A1 (en) * 2021-02-17 2022-08-24 Université de Bordeaux Antimicrobial cationic peptoid and n-subtituted peptidic copolymers, preparation and uses thereof
US20250121121A1 (en) * 2021-06-25 2025-04-17 Maxwell Biosciences, Inc. Substrates modified with peptoid-loaded microgels for resistance to bacterial colonization
US20240316141A1 (en) * 2021-07-16 2024-09-26 The Board Of Trustees Of The Leland Stanford Junior University The Use of Thiourea and Thiourea Derivatives As Potentiators of Antibacterial Activity of Peptoids
US20250268976A1 (en) 2024-02-23 2025-08-28 Maxwell Biosciences, Inc. Broad-spectrum peptoids for treatment or prevention of wound infections, and compositions and methods of use thereof
US20250268809A1 (en) 2024-02-23 2025-08-28 Maxwell Biosciences, Inc. Broad-spectrum peptoids for oral and dental hygiene, and compositions and methods of use thereof
WO2025178965A1 (en) 2024-02-23 2025-08-28 Maxwell Biosciences, Inc. Peptoids for treating filoviridae infections
US20250282821A1 (en) 2024-03-08 2025-09-11 Maxwell Biosciences, Inc. Lipopolysaccharide-binding peptoids, and compositions and methods of use thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9511474D0 (en) * 1995-06-07 1995-08-02 Ciba Geigy Ag Antiviral peptoid compounds
GB0329254D0 (en) * 2003-12-17 2004-01-21 Univ Manchester Treatment of viral infections
CA2714853A1 (en) * 2008-02-08 2009-08-27 Northwestern University Selective poly-n-substituted glycine antibiotics
WO2010098843A2 (en) 2009-02-24 2010-09-02 New York University Peptoid oligomers, pharmaceutical compositions and methods of using the same
US9938321B2 (en) 2013-03-13 2018-04-10 New York University Cyclic peptoid oligomers, pharmaceutical compositions and methods of using the same
US9770504B2 (en) * 2013-05-03 2017-09-26 The Board Of Regents Of The University Of Texas System Generating peptoid vaccines

Also Published As

Publication number Publication date
JP2022532317A (ja) 2022-07-14
EP3962925A4 (en) 2023-08-23
WO2020223581A1 (en) 2020-11-05
JP2024170542A (ja) 2024-12-10
JP7745323B2 (ja) 2025-09-29
US20220213144A1 (en) 2022-07-07
EP3962925A1 (en) 2022-03-09

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