CA3124497A1 - Mitochondrial dna deletions associated with endometriosis - Google Patents

Mitochondrial dna deletions associated with endometriosis Download PDF

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Publication number
CA3124497A1
CA3124497A1 CA3124497A CA3124497A CA3124497A1 CA 3124497 A1 CA3124497 A1 CA 3124497A1 CA 3124497 A CA3124497 A CA 3124497A CA 3124497 A CA3124497 A CA 3124497A CA 3124497 A1 CA3124497 A1 CA 3124497A1
Authority
CA
Canada
Prior art keywords
nucleotide
nucleotides
mtdna
deletion
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3124497A
Other languages
English (en)
French (fr)
Inventor
Jennifer Creed
Andrea Maggrah
Brian Reguly
Andrew Harbottle
Robert USHER
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MDNA LIFE SCIENCES Inc
Original Assignee
MDNA LIFE SCIENCES Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MDNA LIFE SCIENCES Inc filed Critical MDNA LIFE SCIENCES Inc
Publication of CA3124497A1 publication Critical patent/CA3124497A1/en
Pending legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/689Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/36Gynecology or obstetrics
    • G01N2800/364Endometriosis, i.e. non-malignant disorder in which functioning endometrial tissue is present outside the uterine cavity

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Reproductive Health (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CA3124497A 2018-12-22 2019-12-20 Mitochondrial dna deletions associated with endometriosis Pending CA3124497A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862784403P 2018-12-22 2018-12-22
US62/784,403 2018-12-22
US201962931173P 2019-11-05 2019-11-05
US62/931,173 2019-11-05
PCT/US2019/068098 WO2020132596A2 (en) 2018-12-22 2019-12-20 Mitochondrial dna deletions associated with endometriosis

Publications (1)

Publication Number Publication Date
CA3124497A1 true CA3124497A1 (en) 2020-06-25

Family

ID=69185737

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3124497A Pending CA3124497A1 (en) 2018-12-22 2019-12-20 Mitochondrial dna deletions associated with endometriosis

Country Status (9)

Country Link
US (1) US20220251655A1 (enExample)
EP (1) EP3899050A2 (enExample)
JP (2) JP7649745B2 (enExample)
KR (1) KR20210107719A (enExample)
CN (1) CN113227400A (enExample)
AU (2) AU2019401465A1 (enExample)
CA (1) CA3124497A1 (enExample)
SG (1) SG11202106711YA (enExample)
WO (1) WO2020132596A2 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112200270B (zh) * 2020-11-17 2022-12-20 金弗康生物科技(上海)股份有限公司 一种用于纠正高通量组学数据缺失的数据分区填充方法
GB202114374D0 (en) * 2021-10-07 2021-11-24 Univ Edinburgh Endometriosis biomarker
GB202204595D0 (en) * 2022-03-30 2022-05-11 Univ Newcastle Methods dor determining mitochondrial DNA damage
CN115404274A (zh) * 2022-11-01 2022-11-29 广东省生殖科学研究所(广东省生殖医院) 一种甲基化位点在子宫内膜异位症诊断和分型中的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7871778B2 (en) * 2007-04-25 2011-01-18 The Regents Of The University Of California Methods of diagnosing endometriosis
CA2719718C (en) * 2008-03-28 2019-07-02 Mdna Life Sciences Inc. Aberrant mitochondrial dna, associated fusion transcripts and hybridization probes therefor

Also Published As

Publication number Publication date
SG11202106711YA (en) 2021-07-29
AU2026202367A1 (en) 2026-04-16
KR20210107719A (ko) 2021-09-01
WO2020132596A3 (en) 2020-07-23
AU2019401465A1 (en) 2021-07-22
JP2025087867A (ja) 2025-06-10
JP2022514924A (ja) 2022-02-16
EP3899050A2 (en) 2021-10-27
WO2020132596A2 (en) 2020-06-25
JP7649745B2 (ja) 2025-03-21
US20220251655A1 (en) 2022-08-11
CN113227400A (zh) 2021-08-06

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