CA3123084A1 - Dimerizing agent regulated immunoreceptor complexes - Google Patents

Dimerizing agent regulated immunoreceptor complexes Download PDF

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Publication number
CA3123084A1
CA3123084A1 CA3123084A CA3123084A CA3123084A1 CA 3123084 A1 CA3123084 A1 CA 3123084A1 CA 3123084 A CA3123084 A CA 3123084A CA 3123084 A CA3123084 A CA 3123084A CA 3123084 A1 CA3123084 A1 CA 3123084A1
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Canada
Prior art keywords
domain
polypeptide
antibody
binding fragment
antigen binding
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Pending
Application number
CA3123084A
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English (en)
French (fr)
Inventor
Jordan JARJOUR
Alexander ASTRAKHAN
Wai-Hang LEUNG
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2Seventy Bio Inc
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Bluebird Bio Inc
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Publication of CA3123084A1 publication Critical patent/CA3123084A1/en
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
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CA3123084A 2018-12-14 2019-12-13 Dimerizing agent regulated immunoreceptor complexes Pending CA3123084A1 (en)

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