CA3106334C - Method for preparing c-h acidic (meth)acrylates - Google Patents

Method for preparing c-h acidic (meth)acrylates Download PDF

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CA3106334C
CA3106334C CA3106334A CA3106334A CA3106334C CA 3106334 C CA3106334 C CA 3106334C CA 3106334 A CA3106334 A CA 3106334A CA 3106334 A CA3106334 A CA 3106334A CA 3106334 C CA3106334 C CA 3106334C
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intermediate product
diamine
ester
reaction
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CA3106334A1 (en
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Marcel Treskow
Maik Caspari
Thorben Schutz
Steffen Krill
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Evonik Operations GmbH
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00Preparation of carboxylic acid nitriles
    • C07C253/30Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00Preparation of carboxylic acid nitriles
    • C07C253/32Separation; Purification; Stabilisation; Use of additives
    • C07C253/34Separation; Purification
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • C07C255/01Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/17Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and doubly-bound oxygen atoms bound to the same acyclic carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • C07C255/01Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/19Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and carboxyl groups, other than cyano groups, bound to the same saturated acyclic carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F20/00Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride, ester, amide, imide or nitrile thereof
    • C08F20/02Monocarboxylic acids having less than ten carbon atoms, Derivatives thereof
    • C08F20/52Amides or imides
    • C08F20/54Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
    • C08F20/60Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide containing nitrogen in addition to the carbonamido nitrogen

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

The invention relates to a method for preparing C-H acidic (meth)acrylates and the uses thereof.

Description

I
Method for preparing C-H acidic (meth)acrylates The invention relates to a method for preparing C-H acidic (meth)acrylates and the uses thereof.
The prior art contains a method for preparing derivatives of methacrylate compounds based on acetoacetamides and acetoacetates.
Synthesis of C-H acidic monomers based on derivatives of cyanoacetic acid is not possible according to the method described in EP 0013147, although the claim includes this in the description. In EP 0013417, various amino alcohols or diamines and the methacrylate derivatives thereof are reacted with diketene and the corresponding derivatives of acetoacetic acid are obtained thereby. These also represent C-H
acidic compounds. However, diketene is not suitable as a starting material for the synthesis of cyanoacetic acid and the carboxylic acid derivatives thereof (esters, amides etc), even just because the carbon skeleton is a C4 body and cyanoacetic acid is a C3 body. In order to synthesize non-symmetrically substituted diamines, EP 0013147 also makes use of protecting group chemistry in order to temporarily block an amine in order to protect it from a reaction. This is not economical and, because of the additional reaction steps, is expensive in terms of process technology.
Carboxylic acid derivatives of acetoacetic acid readily give coloured complexes, which are unsuitable for a wide variety of clearcoat applications.
It was therefore an object to provide a method for preparing C-H acidic (meth)acrylates based on cyanoacetic acid. It was especially an object to prepare a C-H acidic monomer without a 1,3-diketone structure, as in acetoacetic acid.
A further object consisted in providing hydrolysis-stable (meth)acrylates, so as to enable particularly good storage stability in the product.
The objects were achieved by a method for preparing C-H acidic (meth)acrylates by reacting a diamine (B) with R2: CnHmO,Nly where Date Recue/Date Received 2022-07-12
2 n= 2-15 m= 4-30 x= 0-4 and y= 0-4 with an ester of cyanoacetic acid (A), in order to form the intermediate product (IP).
Most particular preference is given here to using the methyl and ethyl esters (Z = CH3, C2H5) of cyanoacetic acid, since these are widely commercially available, however higher esters are also readily suitable for the reaction. As by-product in this reaction (as would be expected by those skilled in the art), both amino groups of a diamine react with the cyanoacetic acid to give a bis-cyanoacetamide (BP). This reaction is undesirable, since additional method steps would be required in order to separate off BP, which has a negative influence on the economic viability and costs of the method.
o N)t, ,z o o o 1\1 Z m o 0 0 ,711, õ + H2NR2 NH2 -HOZ x N 11 -HOZ R2 , ,:z........z,,.....)( ,R2. ).L....AN '..'"=A ' ' H H H
A B IP BP
It is simpler to work with an excess of diamine, which also has a lower boiling point than the IP, and can therefore be removed more easily than BP, which is just as temperature-sensitive as IP. Surprisingly, the formation of BP is very greatly suppressed even with small excesses of B, for example with an excess of 1.001:1 and, with an excess of 10:1, particularly preferably 4:1, of B, a crude product of >99% IP is obtained after removing the diamine B. The separation of B can in this case be carried out by extraction or crystallization but especially by distillation, preferably under reduced pressure. The IP obtained after removal of B can be further reacted as a crude product with a (meth)acrylate derivative (MAD) without further work-up. Here, the reaction can Date Recue/Date Received 2022-07-12 2a proceed with acid halides (c2) (preferably using bases to scavenge the hydrogen halides forming) and also by reaction with esters of (meth)acrylic acid (c1).
In this regard, a mixture of dioctyltin oxide (DOTO) and isopropyl titanate (IPT) has proven particularly suitable as catalyst. However, the reaction of BP with the acid anhydrides of (meth)acrylic acid (c2) has been shown to be particularly efficient.
o o o o õ +
, RTL,I
R3 _________________________________________ , N)LN,R2,N)-R1 N ;NH2 H H H
IP MAD P
R3 = OMe (Cat: IPT/DOTO) = Halide = 0-CO-C(R1)=CH2 R1 = H, CH3 Surprisingly, it has been found that high conversions are achieved, and the amount of by-products is greatly reduced, with the method according to the invention.
Other aspects of the invention are hereinafter defined with reference to the following preferred embodiments [1] to [15]:
[1] A method for preparing C-H acidic (meth)acrylates of formula (I) CH2=CR1-CO-NH-R2-NH-CO-CH2-CN (I) wherein R1 represents H or methyl and R2 represents a radical of formula CnHmO,Nly wherein n = 2 to 15, m = 4 to 30, x = 0 to 4, and y = 0 to 4;
said method comprising the steps of a) reacting an ester of cyanoacetic acid (A) with a diamine (B) in excess in a reaction solution, b) removing unreacted diamine (B) from the reaction solution, C) obtaining as an intermediate product (IP) from step b), an amino-functionalized cyanoacetamide, Date Regue/Date Received 2022-07-12 2b c1) reacting the amino-functionalized cyanoacetamide with a (meth)acrylic acid ester, or c2) reacting the amino-functionalized cyanoacetamide with a (meth)acrylic anhydride or a (meth)acryloyl halide, and d) obtaining from step c) the C-H acidic (meth)acrylates of formula (I).
[2] The method according to [1], wherein the C-H acidic (meth)acrylates of formula (I) of step d) is further isolated by means of extraction or crystallization.
[3] The method according to [1] or [2], wherein the ester of cyanoacetic acid is selected from the group consisting of methyl cyanoacetate and ethyl cyanoacetate.
[4] The method according to [1] or [2], wherein the diamine is selected from the group consisting of unsubstituted aliphatic diamines, substituted aliphatic diamines, unsubstituted aromatic diamines and substituted aromatic diamines.
[5] The method according to [4], wherein the unsubstituted aliphatic diamines are linear, branched or cyclic, the substituted aliphatic diamines are linear, branched or cyclic, the substituted aromatic diamines are substituted in any one of the ortho, meta or para positions.
[6] The method according to any one of [1] to [5], wherein the excess of the diamine to the ester of cyanoacetic acid is between 10:1 and 1.001:1.
[7] The method according to any one of [1] to [6], wherein the unreacted diamine in step b) is removed by means of distillation, extraction or crystallization.
[8] The method according to any one of [1] to [7], wherein the reaction of the intermediate product in c1) is carried out with a (meth)acrylic acid ester selected from the group consisting of methyl (meth)acrylate, ethyl (meth)acrylate, butyl (meth)acrylate, ethyl acrylate, butyl acrylate and higher alcohols of (meth)acrylate.
[9] The method according to any one of [1] to [7], wherein the intermediate product in c2) is reacted with a (meth)acryloyl halide selected from the group consisting of (meth)acryloyl bromides and (meth)acryloyl chlorides.
Date Recue/Date Received 2022-07-12 2c
[10] The method according to any one of [1] to [7], wherein the intermediate product in c2) is reacted with a (meth)acrylic anhydride selected from the group consisting of methacrylic anhydride and acrylic anhydride.
[11] The method according to any one of [1] to [10], wherein the reaction of the ester of cyanoacetic acid with the diamine takes place at temperatures between -20 C

and 140 C.
[12] The method according to any one of [1] to [10], wherein the reaction of the ester of cyanoacetic acid with the diamine takes place at temperatures between between 0 C and 30 C.
[13] The method according to any one of [1] to [8], wherein the ratio of the (meth)acrylic acid ester to the intermediate product in c1) is between 1.01:1 and 20:1.
[14] The method according to any one of [1] to [7] and [10], wherein the ratio of the (meth)acrylic anhydride to the intermediate product in c2) is between 0.2:1 and 5:1.
[15] The method according to any one of [1] to [7] and [9], wherein the ratio of the (meth)acryloyl halide to the intermediate product in c2) is between 0.2:1 and 5:1.
The notation "(meth)acrylate" here means both methacrylate, for example methyl methacrylate, ethyl methacrylate, etc., and acrylate, for example methyl acrylate, ethyl acrylate, etc., and mixtures of the two.
Date Recue/Date Received 2022-07-12 Dia mines Suitable diamines are selected from the group of aliphatic, linear or branched or cyclic substituted and unsubstituted diamines and aromatic (ortho, meta or para) substituted diamines.
Particular preference is given to diamines selected from the group of ethylenediarnine, 1,3-diaminopropane, 1,4-diaminobutane, 1,5-diaminopentane, 1,6-hexanediamine, 1,7-diaminoheptane, 1,8-diaminooctane, 1,10-diaminodecane, 1,2-diaminopropane, isolated and mixtures of cis and trans isomers of 1,2-diaminocyclohexane, isolated and mixtures of cis and trans isomers of 1,3-diaminocyclohexane, isolated and mixtures of cis and trans isomers of 1,4-diaminocyclohexane, 1,3-diamino-2-hydroxypropane, 2,2-dimethy1-1,3-propanediamine, isolated and mixtures of cis and trans isomers of isophorondiamine, isolated and mixtures of cis and trans isomers of 1,3-cyclohexanebis(methylamine), 4,4'-methylenebis(cyclohexylamine), isolated and mixtures of cis and trans isomers of 4,4'-methylenebis(2-rnethylcyclohexylarnine).
The ratio of alkyl acid anhydride or alkyl acid halide to intermediate product in (c2) is between 0.2:1 and 5:1.
Particular preference is given to reacting at the ratio 0.5:1, since in this case 1 eq. of intermediate product amine neutralizes the acid formed from anhydride or acid halide.
Most particular preference is given to the ratio 1:1, since in this case large portions of the hitherto expensively prepared amine react further to give the product, despite earlier reaction with the carboxylic acid of the anhydride.
It may likewise be preferable to work with an excess of anhydride of >1:1, since this helps to reach full conversion more quickly.
(Meth)acrylic anhydride The intermediate product (IP) in c2) is reacted with (meth)acrylic anhydrides selected from the group of rnethacrylic anhydride and acrylic anhydride.
Reaction conditions The reaction in a is carried out at temperatures between 0-120 C, preferably between 10 and 40 C
during the metering, and at temperatures up to 100 C in the post-reaction phase and preparation for work-up. In c1, in the range 60-140 C, preferably 100-120 C. In c2, 0-40 C, possibly in the post-reaction up to 100 C.
The reaction time lasts 15 min to 10 h.
In order to avoid the formation of undesirable by-products, the temperature is kept as low as possible and an excess of amine is employed in a.

Neutralization and work-up The intermediate product (IP) can be further used without work-up.
Preferred method variants The intermediate product (IP) from step b is taken up in a solvent while it is still hot, since otherwise it would solidify to a glass, and thus reacts considerably better. Suitable solvents are H20, MTBE, THF, acetonitrile, dioxane, MAD and alcohols. The selection is obvious for those skilled in the art, based on the respective purpose of the reaction.
In step c2, a solvent is employed selected from the group of H20, MTBE, THF, acetonitrile, dioxane, MAD and alcohols.
Extraction or crystallization The product (P) can be further used without work-up. If required, it can also have all low boilers removed from it under reduced pressure, be recrystallized by addition of a polar solvent, or be extracted by addition of an immiscible solvent.
It was found that the inventive C-H acidic (meth)acrylates are hydrolysis-stable and hence storage-stable for a long period.
The C-H acidic (meth)acrylates have many fields of use. Preference is given to applications in coatings and paints, especially in clearcoats. Likewise, they may be used as polymerizable monomer for preparing polymers which can crosslink with ketones, aldehydes, isocyanates and activated double bonds at room temperature.
The examples given below better illustrate the present invention, without restricting the invention to the features disclosed therein.

EXAMPLES:
Example 1: Preparation of N-(2-ethylamino)-2-cyanoacetamide 600 g (10.0 mol) of ethylenediamine are initially charged in a 2 I four-necked round-bottomed flask with sabre stirrer, stirrer motor, thermometer and a 500 ml addition funnel.
248 g (2.5 mol) of methylcyanoacetate are metered in thereto dropwise within 60 minutes, such that the reaction temperature does not exceed 30 C. During this time, the four-necked round-bottomed flask is cooled in an ice-water bath. In the course of the addition of methylcyanoacetate, the reaction mixture becomes increasingly pink coloured, and then lilac. To complete the reaction, the reaction mixture is stirred for a further 90 minutes at room temperature.
Subsequently, the excess ethylenediamine is removed under reduced pressure.
For this purpose, the reaction mixture is heated to 100 C (oil bath temperature) and the volatile constituents are distilled off over a period of 2 hours at a pressure of up to 5 mbar.
The product is obtained as a dark, glass-like solid with a purity of 97.9 area% (determined using GC-RV). The product yield is 309 g (95%).
Comparative Example 1: Preparation of N,N'-ethylenebismethacrylamide A 40% aqueous solution of ethylenediamine (25.5 g, 0.17 mol) is initially charged in a 250 ml four-necked round-bottomed flask with sabre stirrer, stirrer motor, thermometer and a 100 ml addition funnel. 26 g (0.17 mol) of methacrylic anhydride are metered in thereto within 60 minutes, such that the reaction temperature does not exceed 30 C. During this time, the four-necked round-bottomed flask is cooled in an ice-water bath. In the course of the addition of methacrylic anhydride, a white solid is formed.
The white solid is separated off by filtration, and dried. It is N,N,1"-ethylenebismethacrylamide with a purity of 74.8 area% (determined using GC-RV). The product yield is 20 g (60%).
Example 2: Preparation of N-(2-cyanoethylamidoethyl)methacrylamide A mixture of 147 g (1.2 mol) of N-(2-ethylamino)-2-cyanacetamide and 600 g (6.0 mol) of methylmethacrylate are initially charged in a 1 I four-necked round-bottomed flask with air inlet, sabre stirrer, stirrer motor, and a 50 cm-long 29 mm-thick mirrored column with random packing, filled with 6x6 Raschig rings. 7 mg (10 ppm) of 4-hydroxy-2,2,6,6-tetramethylpiperidinooxyl and 0.15 g (200 ppm) of hydroquinone nnonomethyl ether are added thereto, followed by 7.4 g of a mixture comprising 65.6 wt% of dioctyltin oxide and 34.4 wt% of tetraisopropyl titanate.

The reaction mixture is heated under reflux, with the methanol forming being distilled off as an azeotrope via the column with random packing. After approximately 3.5 hours, the conversion, determined by GC, is 58%.
Example 3: Preparation of N-(2-cyanoethylamidoethyl)methacrylamide 312 g (2.4 mol) of N-(2-ethylamino)-2-cyanoacetamide from example 1 are dissolved in 468 g of water in a 2 I three-necked round-bottomed flask with sabre stirrer, stirrer motor, thermometer and a 500 ml addition funnel. 370 g (2.4 mol) of niethacrylic anhydride are slowly added dropwise thereto, with a light brown precipitate being formed. The reaction mixture is then stirred for a further 1.5 hours at 80 C.
The resulting clear, dark red reaction mixture has low boilers removed therefrom under reduced pressure, is concentrated down to 646 g, and has 400 g of isopropanol added thereto. This leads to the formation of a precipitate which is separated off by filtration.
The product is obtained as a brown, crystalline solid with a purity of 77.0 area% (determined using GC-RV). The product yield is 346 g (73.9%).
Example 4: Preparation of N-(2-butylamino)-2-cyanoacetamide 353 g (4.0 mol) of 1,4-diarninobutane are melted at approximately 30 C in a 1 I four-necked round-bottomed flask with sabre stirrer, stirrer motor, thermometer and a 250 ml addition funnel. 99 g (1.0 mol) of methylcyanoacetate are metered in dropwise thereto within 30 minutes, such that the reaction temperature remains at approximately 30 C to 40 C. During this time, the four-necked round-bottomed flask is cooled in an ice-water bath. In the course of the addition of methylcyanoacetate, the reaction mixture becomes increasingly intensely yellow coloured. To complete the reaction, the reaction mixture is stirred for a further 90 minutes at room temperature, with the reaction mixture becoming red coloured.
Subsequently, excess 1,4-diaminobutane is removed under reduced pressure. For this purpose, the reaction mixture is heated to 100 C (oil bath temperature) and the volatile constituents are distilled off over a period of 2.5 hours at a pressure of up to 2 mbar.
The product is obtained as a dark, glass-like solid with a purity of 89.1 area% (determined using GC-RV). The product yield is 146 g (84%).
Example 5: Preparation of N-(2-cyanoethylamidobutyl)methacrylamide 360 g (0.93 mol) of N-(2-butylamino)-2-cyanoacetamide from example 4 are dissolved in 540 g of water in a 1 I four-necked round-bottomed flask with sabre stirrer, stirrer motor, thermometer and a 500 ml addition funnel and cooled to 0 C in an ice-water bath. 143 g (0.93 mol) of methacrylic anhydride, dissolved in 300 ml of methanol, are slowly added thereto dropwise.
Subsequently, the reaction mixture is stirred overnight at room temperature, with the reaction mixture becoming green coloured.
The reaction mixture was concentrated under reduced pressure at 80 C and 35 mbar to 263 g. The residue is dissolved in 160 g of isopropanol and the resulting solution is stored at room temperature. This leads to the formation of a precipitate which is separated off by filtration.
The product is obtained as a yellow crystalline solid. The purity is approximately 94.0 area%
(determined using GC-RV).
Example 6: Preparation of N-(2-hexylamino)-2-cyanoacetamide 465 g (4.0 mol) of 1,6-diaminohexane are melted at approximately 41 C in a II
four-necked round-bottomed flask with sabre stirrer, stirrer motor, thermometer and a 250 ml addition funnel. 99 g (1.0 mol) of methylcyanoacetate are metered in thereto dropwise within 30 minutes, such that the reaction temperature remains at approximately 50 C to 75 C. In the course of the addition of methylcyanoacetate, the reaction mixture becomes increasingly intensely yellow coloured. To complete the reaction, the reaction mixture is stirred for a further 90 minutes at approximately 50 C
to 75 C, with the reaction mixture becoming red coloured.
Subsequently, the excess 1,6-diaminohexane is removed under reduced pressure.
For this purpose, the reaction mixture is heated to 120 C (oil bath temperature) and the volatile constituents are distilled off over a period of 4 hours at a pressure of up to 2 mbar.
The product is obtained as a dark, glass-like solid with a purity of approximately 100 area%
(determined using GC-RV). The product yield is 172 g (94%).
Example 7: Preparation of N-(2-cyanoethylannidobutyl)methacrylamide 31 g (0.2 mol) of methacrylic anhydride and 150 g of water are initially charged in a 1 I four-necked round-bottomed flask with sabre stirrer, stirrer motor, thermometer and a 500 ml addition funnel and cooled to 0 C in an ice-water bath.
360 g (0.93 mol) of N-(2-hexylamino)-2-cyanoacetamide from example 6 are dissolved in 3240 g of methanol at 60 C and cooled to room temperature. This solution is added over a period of 30 minutes via the addition funnel to the methacrylic anhydride. The reaction temperature is kept below 20 C. The reaction mixture is then stirred for a further 3 hours at room temperature.
The product formed is detected in the reaction mixture using GC-RV and can be isolated by crystallization from isopropanol.

Analysis Gas chromatography (GC) Instrument: 7820A from Agilent Technologies Column: DB5, 30m, 0 0.250mm, 0.25 pm film Temperature program:
Injection at 60 C, then hold for 2 min. Subsequently heat to 240 C at 20 C/min and after reaching that temperature, hold at 240 C for 8 min.

Claims (14)

9
1. A method for preparing C-H acidic (meth)acrylates of formula (I) CH2=CR1-CO-NH-R2-NH-CO-CH2-CN (1) wherein R1 represents H or methyl and R2 represents a radical of formula CnHmO,Ny wherein n = 2 to 15, m = 4 to 30, x = 0 to 4, and y = 0 to 4;
said method comprising the steps of a) reacting an ester of cyanoacetic acid (A) with a diamine (B) in excess in a reaction solution, b) removing unreacted diamine (B) from the reaction solution, c) obtaining as an intermediate product (IP) from step b), an amino-functionalized cyanoacetamide, cl ) reacting the amino-functionalized cyanoacetamide with a (meth)acrylic acid ester, or c2) reacting the amino-functionalized cyanoacetamide with a (meth)acrylic anhydride or a (meth)acryloyl halide, and d) obtaining from step c) the C-H acidic (meth)acrylates of formula (I).
2. The method according to claim 1, wherein the C-H acidic (meth)acrylates of formula (I) of step d) is further isolated by means of extraction or crystallization.
3. The method according to claim 1 or 2, wherein the ester of cyanoacetic acid is selected from the group consisting of methyl cyanoacetate and ethyl cyanoacetate.
4. The method according to claim 1 or 2, wherein the diamine is selected from the group consisting of unsubstituted aliphatic diamines, substituted aliphatic diamines, unsubstituted aromatic diamines and substituted aromatic diamines.
5. The method according to claim 4, wherein the unsubstituted aliphatic diamines are linear, branched or cyclic, the substituted aliphatic diamines are linear, branched or cyclic, the substituted aromatic diamines are substituted in any one of the ortho, meta or para positions.
6. The method according to any one of claims 1 to 5, wherein the excess of the diamine to the ester of cyanoacetic acid is between 10:1 and 1.001:1.
7. The method according to any one of claims 1 to 6, wherein the unreacted diamine in step b) is removed by means of distillation, extraction or crystallization.
8. The method according to any one of claims 1 to 7, wherein the reaction of the intermediate product in cl ) is carried out with a (meth)acrylic acid ester selected from the group consisting of methyl (meth)acrylate, ethyl (meth)acrylate, butyl (meth)acrylate, ethyl acrylate, butyl acrylate and higher alcohols of (meth)acrylate.
9. The method according to any one of claims 1 to 7, wherein the intermediate product in c2) is reacted with a (meth)acryloyl halide selected from the group consisting of (meth)acryloyl bromides and (meth)acryloyl chlorides.
10. The method according to any one of claims 1 to 7, wherein the intermediate product in c2) is reacted with a (meth)acrylic anhydride selected from the group consisting of methacrylic anhydride and acrylic anhydride.
11. The method according to any one of claims 1 to 10, wherein the reaction of the ester of cyanoacetic acid with the diamine takes place at temperatures between -20 C and 140 C.
12. The method according to any one of claims 1 to 10, wherein the reaction of the ester of cyanoacetic acid with the diamine takes place at temperatures between 0 C and 30 C.
13. The method according to any one of claims 1 to 8, wherein the ratio of the (meth)acrylic acid ester to the intermediate product in cl) is between 1.01:1 and 20:1.
14. The method according to any one of claims 1 to 7 and 10, wherein the ratio of the (meth)acrylic anhydride to the intermediate product in c2) is between 0.2:1 and 5:1.

1 5. The method according to any one of claims 1 to 7 and 9, wherein the ratio of the (meth)acryloyl halide to the intermediate product in c2) is between 0.2:1 and 5:1.
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