CA3105826A1 - Activation mechanism for drug delivery device - Google Patents

Activation mechanism for drug delivery device Download PDF

Info

Publication number
CA3105826A1
CA3105826A1 CA3105826A CA3105826A CA3105826A1 CA 3105826 A1 CA3105826 A1 CA 3105826A1 CA 3105826 A CA3105826 A CA 3105826A CA 3105826 A CA3105826 A CA 3105826A CA 3105826 A1 CA3105826 A1 CA 3105826A1
Authority
CA
Canada
Prior art keywords
engagement region
trigger ring
shield
plunger rod
nut
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3105826A
Other languages
English (en)
French (fr)
Inventor
Matias Melander
Joshua DUDMAN
Joseph Michael Iglesias
Bjarke Lykke Ludvig Svendsen
Adam B. Mccullough
Christian Plambech
Steve Sanchez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amgen Inc
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of CA3105826A1 publication Critical patent/CA3105826A1/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566—Means improving security or handling thereof
    • A61M5/31571—Means preventing accidental administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566—Means improving security or handling thereof
    • A61M5/3157—Means providing feedback signals when administration is completed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
    • A61M5/31585—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by axially moving actuator, e.g. an injection button
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/3159—Dose expelling manners
    • A61M5/31591—Single dose, i.e. individually set dose administered only once from the same medicament reservoir, e.g. including single stroke limiting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3202—Devices for protection of the needle before use, e.g. caps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2006—Having specific accessories
    • A61M2005/2013—Having specific accessories triggering of discharging means by contact of injector with patient body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321—Means for protection against accidental injuries by used needles
    • A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
    • A61M5/326—Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
    • A61M2005/3267—Biased sleeves where the needle is uncovered by insertion of the needle into a patient's body

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
CA3105826A 2018-08-17 2019-08-16 Activation mechanism for drug delivery device Pending CA3105826A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862719367P 2018-08-17 2018-08-17
US62/719,367 2018-08-17
PCT/US2019/046899 WO2020037256A1 (en) 2018-08-17 2019-08-16 Activation mechanism for drug delivery device

Publications (1)

Publication Number Publication Date
CA3105826A1 true CA3105826A1 (en) 2020-02-20

Family

ID=67841181

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3105826A Pending CA3105826A1 (en) 2018-08-17 2019-08-16 Activation mechanism for drug delivery device

Country Status (11)

Country Link
US (2) US20210260302A1 (https=)
EP (1) EP3836988A1 (https=)
JP (3) JP7598766B2 (https=)
CN (2) CN118217484A (https=)
AU (2) AU2019321678B2 (https=)
CA (1) CA3105826A1 (https=)
IL (2) IL279811B2 (https=)
MA (1) MA53227A (https=)
MX (2) MX2021001794A (https=)
SG (1) SG11202013189WA (https=)
WO (1) WO2020037256A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MA53912A (fr) 2018-10-15 2022-01-19 Amgen Inc Dispositif d'administration de médicament comprenant un mécanisme d'amortissement
WO2021214192A1 (de) * 2020-04-24 2021-10-28 Fresenius Kabi Deutschland Gmbh Spritze und spritzenkörper
CN115515667A (zh) * 2020-05-15 2022-12-23 拜康生物制品有限公司 自动注射器组件
CN118019555A (zh) * 2021-10-06 2024-05-10 美国安进公司 用于药物递送装置的撞击激活式固位特征

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5451210A (en) * 1991-04-29 1995-09-19 Lifequest Medical, Inc. System and method for rapid vascular drug delivery
IL160358A0 (en) 2001-08-23 2004-07-25 Genmab As Human antibodies specific for interleukin 15 (il-15)
US20050027255A1 (en) * 2003-07-31 2005-02-03 Sid Technologies, Llc Automatic injector
CN101678167B (zh) * 2007-03-22 2013-09-18 特克法马许可公司 注射装置中的弹簧机构
WO2008113864A1 (de) * 2007-03-22 2008-09-25 Tecpharma Licensing Ag Injektionsvorrichtung mit auslösesicherungen
EP2438941A1 (en) * 2010-10-08 2012-04-11 Sanofi-Aventis Deutschland GmbH Auto injector with a torsion spring
GB201020475D0 (en) * 2010-12-02 2011-01-19 Oval Medical Technologies Ltd Delivery mechanism for an autoinjector
EP2606925A1 (en) * 2011-12-21 2013-06-26 Sanofi-Aventis Deutschland GmbH Autoinjector
WO2013134244A2 (en) * 2012-03-06 2013-09-12 Antares Pharma, Inc. Prefilled syringe with breakaway force feature
JP2016533220A (ja) * 2013-10-16 2016-10-27 ノボ・ノルデイスク・エー／エス 改善された投与量リセット機構を有する薬物送達デバイス
EP3125975B1 (en) * 2014-04-04 2021-06-09 Novo Nordisk A/S Autoinjector having needle shield triggering
JP2017519581A (ja) 2014-06-27 2017-07-20 ノボ・ノルデイスク・エー／エス 針シールドトリガー部を有する自動注射器
US10695499B2 (en) * 2015-10-30 2020-06-30 Novo Nordisk A/S Method of manufacturing prefilled drug delivery devices
US20180140783A1 (en) * 2016-11-22 2018-05-24 E3D Agricultural Cooperative Association Ltd Actuated needle shielding and shething device
JP7419339B2 (ja) * 2018-07-24 2024-01-22 アンタレス・ファーマ・インコーポレーテッド 注射器

Also Published As

Publication number Publication date
IL279811B2 (en) 2025-03-01
AU2025200635A1 (en) 2025-02-20
MX2024013000A (es) 2024-11-08
CN112469455A (zh) 2021-03-09
JP2026021404A (ja) 2026-02-10
CN112469455B (zh) 2024-03-22
JP7598766B2 (ja) 2024-12-12
WO2020037256A1 (en) 2020-02-20
JP7766775B2 (ja) 2025-11-10
AU2019321678A1 (en) 2021-01-28
IL279811B1 (en) 2024-11-01
US20250152838A1 (en) 2025-05-15
JP2025027087A (ja) 2025-02-26
EP3836988A1 (en) 2021-06-23
US20210260302A1 (en) 2021-08-26
IL279811A (en) 2021-03-01
AU2019321678B2 (en) 2024-11-07
IL316307A (en) 2024-12-01
MX2021001794A (es) 2021-04-19
JP2021533844A (ja) 2021-12-09
MA53227A (fr) 2021-11-24
SG11202013189WA (en) 2021-01-28
CN118217484A (zh) 2024-06-21

Similar Documents

Publication Publication Date Title
US12440625B2 (en) Drug delivery device
US20250099682A1 (en) Drug delivery device
US12311151B2 (en) Drug delivery device
US20210093792A1 (en) Drug delivery device and methods of delivering a drug
US20250152838A1 (en) Activation mechanism for drug delivery device
US12551623B2 (en) Drug delivery device having a needle guard mechanism with a turnable threshold of resistance to needle guard movement
AU2020340905B2 (en) Activatable injection device for drug delivery
US12151089B2 (en) Drug delivery device having dose indicator
TWI857975B (zh) 具有內部力傳遞的用於藥物遞送之注射系統
HK40111821A (zh) 用於药物递送装置的启动机构

Legal Events

Date Code Title Description
MFA Maintenance fee for application paid

Free format text: FEE DESCRIPTION TEXT: MF (APPLICATION, 5TH ANNIV.) - STANDARD

Year of fee payment: 5

U00 Fee paid

Free format text: ST27 STATUS EVENT CODE: A-1-1-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED

Effective date: 20240726

D11 Substantive examination requested

Free format text: ST27 STATUS EVENT CODE: A-1-1-D10-D11-D117 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: REQUEST FOR EXAMINATION RECEIVED

Effective date: 20241101

W00 Other event occurred

Free format text: ST27 STATUS EVENT CODE: A-1-1-W10-W00-W111 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: CORRESPONDENT DETERMINED COMPLIANT

Effective date: 20241101

D00 Search and/or examination requested or commenced

Free format text: ST27 STATUS EVENT CODE: A-1-1-D10-D00-D118 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: REQUEST FOR EXAMINATION REQUIREMENTS DETERMINED COMPLIANT

Effective date: 20241115

U11 Full renewal or maintenance fee paid

Free format text: ST27 STATUS EVENT CODE: A-1-1-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT DETERMINED COMPLIANT

Effective date: 20241217

Free format text: ST27 STATUS EVENT CODE: A-1-1-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL

Effective date: 20241217

W00 Other event occurred

Free format text: ST27 STATUS EVENT CODE: A-1-1-W10-W00-W100 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: LETTER SENT

Effective date: 20250410

D11 Substantive examination requested

Free format text: ST27 STATUS EVENT CODE: A-1-2-D10-D11-D155 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: ALL REQUIREMENTS FOR EXAMINATION DETERMINED COMPLIANT

Effective date: 20250430

MFA Maintenance fee for application paid

Free format text: FEE DESCRIPTION TEXT: MF (APPLICATION, 6TH ANNIV.) - STANDARD

Year of fee payment: 6

U00 Fee paid

Free format text: ST27 STATUS EVENT CODE: A-2-2-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED

Effective date: 20250724

U11 Full renewal or maintenance fee paid

Free format text: ST27 STATUS EVENT CODE: A-2-2-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL

Effective date: 20250826

D15 Examination report completed

Free format text: ST27 STATUS EVENT CODE: A-2-2-D10-D15-D126 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: EXAMINER'S REPORT

Effective date: 20260319