CA3096048A1 - Microfluidic systems and methods to denude mammalian oocytes - Google Patents

Microfluidic systems and methods to denude mammalian oocytes Download PDF

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Publication number
CA3096048A1
CA3096048A1 CA3096048A CA3096048A CA3096048A1 CA 3096048 A1 CA3096048 A1 CA 3096048A1 CA 3096048 A CA3096048 A CA 3096048A CA 3096048 A CA3096048 A CA 3096048A CA 3096048 A1 CA3096048 A1 CA 3096048A1
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CA
Canada
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teeth
units
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3096048A
Other languages
English (en)
French (fr)
Inventor
Lindong WENG
Gloria Y. LEE
Mehmet Toner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
General Hospital Corp
Original Assignee
General Hospital Corp
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Filing date
Publication date
Application filed by General Hospital Corp filed Critical General Hospital Corp
Publication of CA3096048A1 publication Critical patent/CA3096048A1/en
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D19/00—Instruments or methods for reproduction or fertilisation
    • A61D19/02—Instruments or methods for reproduction or fertilisation for artificial insemination
    • A61D19/027—Devices for injecting semen into animals, e.g. syringes, guns, probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/16—Microfluidic devices; Capillary tubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D19/00—Instruments or methods for reproduction or fertilisation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D19/00—Instruments or methods for reproduction or fertilisation
    • A61D19/02—Instruments or methods for reproduction or fertilisation for artificial insemination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D19/00—Instruments or methods for reproduction or fertilisation
    • A61D19/04—Instruments or methods for reproduction or fertilisation for embryo transplantation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/06—Bioreactors or fermenters specially adapted for specific uses for in vitro fertilization
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M3/00—Tissue, human, animal or plant cell, or virus culture apparatus
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles or throttle valves

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Reproductive Health (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Clinical Laboratory Science (AREA)
  • Dispersion Chemistry (AREA)
  • Transplantation (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Animal Husbandry (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
CA3096048A 2018-04-04 2019-04-04 Microfluidic systems and methods to denude mammalian oocytes Pending CA3096048A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862652648P 2018-04-04 2018-04-04
US62/652,648 2018-04-04
US201862732884P 2018-09-18 2018-09-18
US62/732,884 2018-09-18
PCT/US2019/025895 WO2019195620A1 (en) 2018-04-04 2019-04-04 Microfluidic systems and methods to denude mammalian oocytes

Publications (1)

Publication Number Publication Date
CA3096048A1 true CA3096048A1 (en) 2019-10-10

Family

ID=68101522

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3096048A Pending CA3096048A1 (en) 2018-04-04 2019-04-04 Microfluidic systems and methods to denude mammalian oocytes

Country Status (8)

Country Link
US (1) US12383389B2 (https=)
EP (1) EP3774050A4 (https=)
JP (1) JP7539836B2 (https=)
CN (1) CN112154031B (https=)
AU (1) AU2019247412B2 (https=)
CA (1) CA3096048A1 (https=)
IL (1) IL277771A (https=)
WO (1) WO2019195620A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022010894A1 (en) 2020-07-06 2022-01-13 Cornell University Methods and devices for automated microfluidic oocyte denudation

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022081966A1 (en) * 2020-10-16 2022-04-21 Overture Life, Inc. Microfluidic devices and methods for denudation of cells
US20250154454A1 (en) * 2021-12-20 2025-05-15 The General Hospital Corporation Microfluidic systems and methods for isolating target entities
WO2025034894A1 (en) * 2023-08-08 2025-02-13 Autoivf, Inc. Devices and methods for isolation of biological entities in suspension

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US4802591A (en) 1986-08-29 1989-02-07 Rotex, Inc. Louvered chip screener
IL146072A0 (en) 1999-04-23 2002-07-25 Monica Palacios Boyce Microelectromechanical devices useful for manipulating cells or embryos, kits thereof, methods of making same, and methods of use thereof
US20060128006A1 (en) * 1999-11-10 2006-06-15 Gerhardt Antimony L Hydrodynamic capture and release mechanisms for particle manipulation
CA2408616C (en) * 2000-05-12 2007-10-02 The Board Of Trustees Of The University Of Illinois Microfluidic channel embryo and/or oocyte handling, analysis and biological evaluation
US6648917B2 (en) * 2001-10-17 2003-11-18 Medicinelodge, Inc. Adjustable bone fusion implant and method
WO2006031385A2 (en) * 2004-08-24 2006-03-23 The General Hospital Corporation Particle separating devices, systems and methods
GB0505377D0 (en) * 2005-03-16 2005-04-20 Robio Systems Ltd Capilliary devices for cell and embryo culture
US20070059680A1 (en) * 2005-09-15 2007-03-15 Ravi Kapur System for cell enrichment
US20070059719A1 (en) * 2005-09-15 2007-03-15 Michael Grisham Business methods for prenatal Diagnosis
UY31720A1 (es) * 2008-03-19 2009-09-30 Procedimiento y aparato para separar particulas en un fluido
SG184592A1 (en) * 2011-03-18 2012-10-30 Univ Singapore Isolating target cells from a biological fluid
EP2251028A1 (en) * 2009-05-12 2010-11-17 Biocompatibles Uk Ltd. Treatment of eye diseases using encapsulated cells encoding and secreting an anti-angiogenic factor and/or a neuroprotective factor
KR20120096175A (ko) * 2011-02-22 2012-08-30 엘지전자 주식회사 태양전지 모듈용 프레임 시스템
AU2012271412A1 (en) * 2011-06-15 2014-01-09 Jeffrey T. Borenstein Device and method for culturing cells in a biomimetic environment
PT2768942T (pt) * 2011-10-17 2020-01-21 Massachusetts Inst Technology Entrega intracelular
ES2725825T3 (es) 2012-04-16 2019-09-27 Univ Cornell Sistema de fertilización asistida por inyección de esperma intracitoplasmática automatizada
US9580678B2 (en) * 2013-06-21 2017-02-28 The Regents Of The University Of California Microfluidic tumor tissue dissociation device
US10137673B2 (en) * 2013-12-31 2018-11-27 Canon U.S. Life Sciences, Inc. Methods and systems for continuous flow cell lysis in a microfluidic device
CN104055560B (zh) * 2014-07-06 2016-03-02 长沙傲图生物科技有限公司 一种电动剥卵装置及其剥卵方法
CA2966623C (en) * 2014-11-03 2024-02-20 The General Hospital Corporation Concentrating particles in a microfluidic device
DE102015116391B4 (de) * 2015-09-28 2017-04-27 Marion Vollmer Medizinische Vorrichtung für die selektive Separierung einer biologischen Probe
WO2017131254A1 (ko) * 2016-01-28 2017-08-03 (주)바이오필리아 유전자 또는 생물학적 물질의 분리 및 검사 키트
WO2017173373A1 (en) 2016-03-31 2017-10-05 Massachusetts Institute Of Technology Flow-through microfluidic methods and devices featuring membrane-perturbing surface interactions for intracellular delivery

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022010894A1 (en) 2020-07-06 2022-01-13 Cornell University Methods and devices for automated microfluidic oocyte denudation
EP4175568A4 (en) * 2020-07-06 2024-07-10 Cornell University METHODS AND DEVICES FOR AUTOMATED MICROFLUIDIC OOCYTE DENUDATION

Also Published As

Publication number Publication date
IL277771A (en) 2020-11-30
EP3774050A4 (en) 2021-06-30
EP3774050A1 (en) 2021-02-17
JP7539836B2 (ja) 2024-08-26
AU2019247412B2 (en) 2023-07-06
WO2019195620A1 (en) 2019-10-10
US20210161635A1 (en) 2021-06-03
AU2019247412A1 (en) 2020-10-29
US12383389B2 (en) 2025-08-12
CN112154031A (zh) 2020-12-29
CN112154031B (zh) 2023-05-23
JP2021520785A (ja) 2021-08-26

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