CA3087572A1 - Composition de conjugue polysaccharide-proteine pneumococcique multivalent - Google Patents
Composition de conjugue polysaccharide-proteine pneumococcique multivalent Download PDFInfo
- Publication number
- CA3087572A1 CA3087572A1 CA3087572A CA3087572A CA3087572A1 CA 3087572 A1 CA3087572 A1 CA 3087572A1 CA 3087572 A CA3087572 A CA 3087572A CA 3087572 A CA3087572 A CA 3087572A CA 3087572 A1 CA3087572 A1 CA 3087572A1
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- CA
- Canada
- Prior art keywords
- serotype
- serotypes
- polysaccharide
- crm197
- conjugated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Abstract
La présente invention concerne des compositions de conjugué pneumococcique multivalent, à support mixte comprenant 21 conjugués polysaccharide-protéine capsulaire pneumococcique différents, chacun des conjugués comprenant un polysaccharide capsulaire d'un sérotype différent de Streptococcus pneumoniae conjugué à l'anatoxine tétanique (TT) ou à CRM197, les sérotypes de Streptococcus pneumoniae étant choisis parmi 1, 3, 4, 5, 6A, 6B, 7F, 8, 9N, 9V, 10A, 11A, 12F, 14, 15B, 18C, 19A, 19F, 22F, 23F et 33F, les polysaccharides capsulaires de deux sérotypes des sérotypes 1, 3 et 5 étant conjugués à TT et les polysaccharides capsulaires restants étant conjugués à CRM197. L'invention concerne en outre des procédés de production des compositions de conjugué pneumococcique multivalent à support mixte et des procédés d'utilisation de celles-ci pour la prophylaxie d'une infection ou d'une maladie due à Streptococcus pneumoniae chez un sujet.
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US201862626482P | 2018-02-05 | 2018-02-05 | |
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KR10-2018-0045246 | 2018-04-18 | ||
PCT/US2019/016506 WO2019152921A1 (fr) | 2018-02-05 | 2019-02-04 | Composition de conjugué polysaccharide-protéine pneumococcique multivalent |
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CA3087572A1 true CA3087572A1 (fr) | 2019-08-08 |
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US (2) | US11147864B2 (fr) |
EP (1) | EP3749358A4 (fr) |
JP (1) | JP7288451B2 (fr) |
KR (1) | KR20200121822A (fr) |
CN (1) | CN111757754B (fr) |
AU (1) | AU2019215212A1 (fr) |
BR (1) | BR112020014978A2 (fr) |
CA (1) | CA3087572A1 (fr) |
IL (1) | IL276229B2 (fr) |
MX (1) | MX2020007939A (fr) |
PH (1) | PH12020551147A1 (fr) |
SA (1) | SA520412580B1 (fr) |
SG (1) | SG11202006387QA (fr) |
TW (1) | TWI815860B (fr) |
WO (1) | WO2019152921A1 (fr) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
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US11160855B2 (en) * | 2014-01-21 | 2021-11-02 | Pfizer Inc. | Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof |
TWI789357B (zh) | 2016-08-05 | 2023-01-11 | 南韓商Sk生物科技股份有限公司 | 多價肺炎球菌多醣-蛋白質共軛物組成物(二) |
CA3031797A1 (fr) | 2016-08-05 | 2018-02-08 | Sanofi Pasteur, Inc. | Composition d'un conjugue polysaccharide-proteine pneumococcique multivalent |
US11951165B2 (en) | 2016-12-30 | 2024-04-09 | Vaxcyte, Inc. | Conjugated vaccine carrier proteins |
CN118662649A (zh) | 2016-12-30 | 2024-09-20 | Vaxcyte公司 | 具有非天然氨基酸的多肽-抗原缀合物 |
US10729763B2 (en) | 2017-06-10 | 2020-08-04 | Inventprise, Llc | Mixtures of polysaccharide-protein pegylated compounds |
CN111683678B (zh) | 2017-12-06 | 2024-01-26 | 默沙东有限责任公司 | 包含肺炎链球菌多糖蛋白缀合物的组合物及其使用方法 |
JP6950099B2 (ja) | 2018-02-05 | 2021-10-13 | サノフィ パスツール インコーポレイティッド | 多価肺炎球菌多糖体−タンパク質複合体組成物 |
BR112020021296A2 (pt) | 2018-04-18 | 2021-01-26 | Sk Bioscience Co., Ltd. | polissacarídeo capsular de streptococcus pneumoniae e conjugado imunogênico do mesmo |
SG11202106541WA (en) | 2018-12-19 | 2021-07-29 | Merck Sharp & Dohme | Compositions comprising streptococcus pneumoniae polysaccharide-protein conjugates and methods of use thereof |
EP4003410A1 (fr) | 2019-07-31 | 2022-06-01 | Sanofi Pasteur, Inc. | Compositions de conjugués de polysaccharide-protéine pneumococcique multivalents leurs méthodes d'utilisation |
US20230183765A1 (en) * | 2020-05-14 | 2023-06-15 | Serum Institute Of India Private Limited | Methods for simultaneous fragmentation and purification of bacterial polysaccharides |
AU2022342080A1 (en) | 2021-09-09 | 2024-03-28 | Affinivax, Inc. | Multivalent pneumococcal vaccines |
WO2024110839A2 (fr) | 2022-11-22 | 2024-05-30 | Pfizer Inc. | Compositions immunogènes comprenant des antigènes saccharidiques capsulaires conjugués et leurs utilisations |
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EP0831894A1 (fr) | 1995-06-07 | 1998-04-01 | Alberta Research Council | Compositions oligasaccharidiques immunogenes et immunostimulatrices et leurs procedes de production et d'utilisations |
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CA2153730A1 (fr) | 1995-07-12 | 1997-01-13 | Andrew J. Malcolm | Activite immunostimulatrice d'un oligosaccharide de serotype 8 de streptococcus pneumoniae |
US5866132A (en) | 1995-06-07 | 1999-02-02 | Alberta Research Council | Immunogenic oligosaccharide compositions |
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AU2007200116A1 (en) | 2001-04-03 | 2007-02-01 | Glaxosmithkline Biologicals S.A. | Vaccine composition |
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2019
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- 2019-02-04 CN CN201980009513.XA patent/CN111757754B/zh active Active
- 2019-02-04 JP JP2020541746A patent/JP7288451B2/ja active Active
- 2019-02-04 KR KR1020207025714A patent/KR20200121822A/ko not_active Application Discontinuation
- 2019-02-04 CA CA3087572A patent/CA3087572A1/fr active Pending
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- 2019-02-04 EP EP19747393.7A patent/EP3749358A4/fr active Pending
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JP2021512870A (ja) | 2021-05-20 |
KR20200121822A (ko) | 2020-10-26 |
IL276229A (en) | 2020-09-30 |
TWI815860B (zh) | 2023-09-21 |
WO2019152921A1 (fr) | 2019-08-08 |
JP7288451B2 (ja) | 2023-06-07 |
CN111757754A (zh) | 2020-10-09 |
BR112020014978A2 (pt) | 2020-12-22 |
TW201945028A (zh) | 2019-12-01 |
US20200360502A1 (en) | 2020-11-19 |
IL276229B1 (en) | 2023-09-01 |
PH12020551147A1 (en) | 2021-05-31 |
US20220031828A1 (en) | 2022-02-03 |
EP3749358A4 (fr) | 2022-04-20 |
IL276229B2 (en) | 2024-01-01 |
MX2020007939A (es) | 2020-09-03 |
SA520412580B1 (ar) | 2024-02-21 |
EP3749358A1 (fr) | 2020-12-16 |
US11147864B2 (en) | 2021-10-19 |
AU2019215212A1 (en) | 2020-07-23 |
SG11202006387QA (en) | 2020-07-29 |
CN111757754B (zh) | 2024-07-05 |
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