CA3085062C - Nicotine tablet - Google Patents

Nicotine tablet Download PDF

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Publication number
CA3085062C
CA3085062C CA3085062A CA3085062A CA3085062C CA 3085062 C CA3085062 C CA 3085062C CA 3085062 A CA3085062 A CA 3085062A CA 3085062 A CA3085062 A CA 3085062A CA 3085062 C CA3085062 C CA 3085062C
Authority
CA
Canada
Prior art keywords
nicotine
tablet
seconds
tablet according
fdt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA3085062A
Other languages
English (en)
French (fr)
Other versions
CA3085062A1 (en
Inventor
Bruno Provstgaard Nielsen
Kent Albin Nielsen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fertin Pharma AS
Original Assignee
Fertin Pharma AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=64744343&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA3085062(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Fertin Pharma AS filed Critical Fertin Pharma AS
Publication of CA3085062A1 publication Critical patent/CA3085062A1/en
Application granted granted Critical
Publication of CA3085062C publication Critical patent/CA3085062C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465—Nicotine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Addiction (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Neurology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA3085062A 2017-12-08 2018-12-07 Nicotine tablet Active CA3085062C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA201770925 2017-12-08
DKPA201770925 2017-12-08
PCT/DK2018/050335 WO2019110072A1 (en) 2017-12-08 2018-12-07 Nicotine tablet

Publications (2)

Publication Number Publication Date
CA3085062A1 CA3085062A1 (en) 2019-06-13
CA3085062C true CA3085062C (en) 2022-08-16

Family

ID=64744343

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3085062A Active CA3085062C (en) 2017-12-08 2018-12-07 Nicotine tablet

Country Status (10)

Country Link
US (3) US11738016B2 (enExample)
EP (2) EP3906916A1 (enExample)
JP (1) JP7278281B2 (enExample)
CN (1) CN111447921B (enExample)
AU (1) AU2018378648B2 (enExample)
CA (1) CA3085062C (enExample)
DK (1) DK3720418T3 (enExample)
ES (1) ES2890975T3 (enExample)
PL (1) PL3720418T3 (enExample)
WO (1) WO2019110072A1 (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2018378648B2 (en) 2017-12-08 2021-06-03 Fertin Pharma A/S Nicotine tablet
CA3085065C (en) 2017-12-08 2023-12-05 Fertin Pharma A/S Formulations providing high nicotine concentrations
US11826462B2 (en) 2019-12-09 2023-11-28 Nicoventures Trading Limited Oral product with sustained flavor release
US11872231B2 (en) 2019-12-09 2024-01-16 Nicoventures Trading Limited Moist oral product comprising an active ingredient
US11617744B2 (en) 2019-12-09 2023-04-04 Nico Ventures Trading Limited Moist oral compositions
US11969502B2 (en) 2019-12-09 2024-04-30 Nicoventures Trading Limited Oral products
US12439949B2 (en) 2019-12-09 2025-10-14 Nicoventures Trading Limited Oral compositions with reduced water activity
US11793230B2 (en) 2019-12-09 2023-10-24 Nicoventures Trading Limited Oral products with improved binding of active ingredients
US12310959B2 (en) 2019-12-09 2025-05-27 Nicoventures Trading Limited Oral compositions with reduced water content
US12433321B2 (en) 2019-12-09 2025-10-07 Nicoventures Trading Limited Oral composition with beet material
US12439952B2 (en) 2019-12-09 2025-10-14 Nicoventures Trading Limited Moist oral compositions
AU2021289162A1 (en) 2020-06-08 2023-02-09 Nicoventures Trading Limited Effervescent oral composition comprising an active ingredient
US11382861B1 (en) * 2020-12-17 2022-07-12 Nirajkumar Karneshbhai Patel Nicotine pouch
JP2024523520A (ja) 2021-06-25 2024-06-28 ニコベンチャーズ トレーディング リミテッド 経口製品及び製造方法
WO2023007440A1 (en) 2021-07-30 2023-02-02 Nicoventures Trading Limited Aerosol generating substrate comprising microcrystalline cellulose
CN113827575A (zh) * 2021-11-02 2021-12-24 上海普康药业有限公司 一种利伐沙班片剂及其制备方法
CN115969898A (zh) * 2023-02-09 2023-04-18 东莞市吉纯生物技术有限公司 一种防治口腔溃疡的口含烟含片及其制备方法
WO2025056129A1 (en) 2023-09-12 2025-03-20 Fertin Pharma A/S Orally disintegrating nicotine tablet for use under lip
EP4543417A1 (en) 2023-09-12 2025-04-30 Fertin Pharma A/S Orally disintegrating nicotine tablet for use under lip

Family Cites Families (46)

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US5549906A (en) 1993-07-26 1996-08-27 Pharmacia Ab Nicotine lozenge and therapeutic method for smoking cessation
US5810018A (en) * 1994-12-29 1998-09-22 Monte; Woodrow C. Method, composition and apparatus for reducing the incidence of cigarette smoking
EP1128817A1 (en) 1998-10-27 2001-09-05 Biovail Technologies Ltd Microparticles containing peg and/or peg glyceryl esters
US20010016593A1 (en) 1999-04-14 2001-08-23 Wilhelmsen Paul C. Element giving rapid release of nicotine for transmucosal administration
US6583160B2 (en) * 1999-04-14 2003-06-24 Steve Smith Nicotine therapy method and oral carrier for assuaging tobacco-addiction
US6248760B1 (en) 1999-04-14 2001-06-19 Paul C Wilhelmsen Tablet giving rapid release of nicotine for transmucosal administration
US6544552B2 (en) 2001-01-11 2003-04-08 Particle And Coating Technologies, Inc. Method of producing porous tablets with improved dissolution properties
RU2003129506A (ru) * 2001-03-06 2005-03-10 Киова Хакко Когио Ко., Лтд. (Jp) Быстрораспадающаяся во рту таблетка
CA2449415A1 (en) 2001-04-20 2002-10-31 Lavipharm Laboratories Inc. Intraoral delivery of nicotine for smoking cessation
US20060057207A1 (en) 2001-11-30 2006-03-16 Pfizer Inc Fast-disintegrating dosage forms of 5,8,14-triazatetracyclo[10.3.1.02,11.04,9]-hexadeca-2(11),3,5,7,9-pentaene
SE0104388D0 (sv) 2001-12-27 2001-12-27 Pharmacia Ab New formulation and use and manufacture thereof
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US7387788B1 (en) * 2003-10-10 2008-06-17 Antares Pharma Ipl Ag Pharmaceutical compositions of nicotine and methods of use thereof
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US20070196474A1 (en) 2004-04-30 2007-08-23 Withiam Michael C Rapidly disintegrating low friability tablets comprising calcium carbonate
WO2007071580A1 (de) 2005-12-21 2007-06-28 Basf Se Feinteiliges quervernetztes polyvinylpyrrolidon als tablettensprengmittel
US20070269386A1 (en) 2006-05-16 2007-11-22 Per Steen New product and use and manufacture thereof
US20070269492A1 (en) * 2006-05-16 2007-11-22 Per Steen New product and use and manufacture thereof
BRPI0716995A2 (pt) 2006-09-27 2013-10-15 Niconovum Ab Métodos para administração oral de um líquido, e para aplicação de gotículas líquidas ou líquido atomizado contendo uma substância ativa no interior da boca de um indivíduo, dispositivo de pulverização, uso de um líquido, kit, e, uso de um kit
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US20080286340A1 (en) * 2007-05-16 2008-11-20 Sven-Borje Andersson Buffered nicotine containing products
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AR071420A1 (es) * 2008-05-01 2010-06-16 Smithkline Beecham Corp Composicion de pastilla para chupar oral que comprende un principio activo de nicotina y procedimiento para fabricarla
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NZ591710A (en) * 2008-10-14 2012-11-30 Mcneil Ab Controlled release oral dosage form comprising at least one portion that is rapidly disintegrating and at least one portion that is slowly disintegrating
US20110274628A1 (en) 2010-05-07 2011-11-10 Borschke August J Nicotine-containing pharmaceutical compositions
WO2012085043A2 (en) 2010-12-22 2012-06-28 Basf Se Rapidly disintegrating, solid coated dosage form
SE535587C2 (sv) 2011-03-29 2012-10-02 Chill Of Sweden Ab Produkt innehållande ett fritt nikotinsalt och en ej vattenlöslig påse
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CA3085064C (en) 2017-12-08 2023-10-24 Fertin Pharma A/S Nicotine mouth spray
CA3085065C (en) 2017-12-08 2023-12-05 Fertin Pharma A/S Formulations providing high nicotine concentrations
PL3720496T3 (pl) 2017-12-08 2025-04-28 Fertin Pharma A/S Stały doustny preparat nikotynowy
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Also Published As

Publication number Publication date
JP7278281B2 (ja) 2023-05-19
CN111447921A (zh) 2020-07-24
EP3906916A1 (en) 2021-11-10
EP3720418A1 (en) 2020-10-14
PL3720418T3 (pl) 2021-12-20
AU2018378648B2 (en) 2021-06-03
DK3720418T3 (da) 2021-10-11
US11738016B2 (en) 2023-08-29
ES2890975T3 (es) 2022-01-25
CN111447921B (zh) 2023-10-13
US12433881B2 (en) 2025-10-07
AU2018378648A1 (en) 2020-07-23
US20190175581A1 (en) 2019-06-13
US20240285610A1 (en) 2024-08-29
US20230346768A1 (en) 2023-11-02
JP2021505546A (ja) 2021-02-18
EP3720418B1 (en) 2021-08-04
CA3085062A1 (en) 2019-06-13
US12005058B2 (en) 2024-06-11
WO2019110072A1 (en) 2019-06-13

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20201217

EEER Examination request

Effective date: 20201217

EEER Examination request

Effective date: 20201217

EEER Examination request

Effective date: 20201217