CA3083064A1 - Spray-dried thrombin and methods of using and making spray-dried thrombin - Google Patents

Spray-dried thrombin and methods of using and making spray-dried thrombin Download PDF

Info

Publication number
CA3083064A1
CA3083064A1 CA3083064A CA3083064A CA3083064A1 CA 3083064 A1 CA3083064 A1 CA 3083064A1 CA 3083064 A CA3083064 A CA 3083064A CA 3083064 A CA3083064 A CA 3083064A CA 3083064 A1 CA3083064 A1 CA 3083064A1
Authority
CA
Canada
Prior art keywords
spray
thrombin
dried
hemostatic
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA3083064A
Other languages
English (en)
French (fr)
Inventor
Alexander Wesley Scott
Paul Jeffrey SANDERS
Alyssa SANDERS
Adam Christopher MERCER
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baxter Healthcare SA
Baxter International Inc
Original Assignee
Baxter Healthcare SA
Baxter International Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter Healthcare SA, Baxter International Inc filed Critical Baxter Healthcare SA
Publication of CA3083064A1 publication Critical patent/CA3083064A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0028—Polypeptides; Proteins; Degradation products thereof
    • A61L26/0047—Specific proteins or polypeptides not covered by groups A61L26/0033 - A61L26/0042
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/10—Polypeptides; Proteins
    • A61L24/104—Gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0031—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/10—Polypeptides; Proteins
    • A61L24/108—Specific proteins or polypeptides not covered by groups A61L24/102 - A61L24/106
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/008—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/04—Materials for stopping bleeding

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Surgery (AREA)
  • Dispersion Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA3083064A 2017-12-29 2018-12-20 Spray-dried thrombin and methods of using and making spray-dried thrombin Abandoned CA3083064A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762611963P 2017-12-29 2017-12-29
US62/611,963 2017-12-29
US201862771936P 2018-11-27 2018-11-27
US62/771,936 2018-11-27
PCT/US2018/066838 WO2019133440A1 (en) 2017-12-29 2018-12-20 Spray-dried thrombin and methods of using and making spray-dried thrombin

Publications (1)

Publication Number Publication Date
CA3083064A1 true CA3083064A1 (en) 2019-07-04

Family

ID=65024106

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3083064A Abandoned CA3083064A1 (en) 2017-12-29 2018-12-20 Spray-dried thrombin and methods of using and making spray-dried thrombin

Country Status (11)

Country Link
US (1) US11583610B2 (enExample)
EP (1) EP3731885B1 (enExample)
JP (1) JP2021508507A (enExample)
KR (1) KR20200105680A (enExample)
CN (1) CN111787958A (enExample)
AU (1) AU2018396037A1 (enExample)
BR (1) BR112020011034A2 (enExample)
CA (1) CA3083064A1 (enExample)
MX (1) MX2020006856A (enExample)
SG (1) SG11202005231RA (enExample)
WO (1) WO2019133440A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2022398334A1 (en) 2021-11-29 2024-05-02 Baxter Healthcare Sa Improved hemostat reconstitution methods and devices
WO2023115427A1 (en) 2021-12-23 2023-06-29 Guangzhou Bioseal Biotech Co., Ltd. Spray dried thrombin

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6066325A (en) 1996-08-27 2000-05-23 Fusion Medical Technologies, Inc. Fragmented polymeric compositions and methods for their use
US6706690B2 (en) 1999-06-10 2004-03-16 Baxter Healthcare Corporation Hemoactive compositions and methods for their manufacture and use
US8303981B2 (en) 1996-08-27 2012-11-06 Baxter International Inc. Fragmented polymeric compositions and methods for their use
US6063061A (en) 1996-08-27 2000-05-16 Fusion Medical Technologies, Inc. Fragmented polymeric compositions and methods for their use
US7435425B2 (en) 2001-07-17 2008-10-14 Baxter International, Inc. Dry hemostatic compositions and methods for their preparation
US8603511B2 (en) 1996-08-27 2013-12-10 Baxter International, Inc. Fragmented polymeric compositions and methods for their use
DE19859611C2 (de) * 1998-12-23 2003-07-03 Aventis Behring Gmbh Fibrinklebergranulat und Verfahren zu dessen Herstellung
US7572769B2 (en) * 1998-12-23 2009-08-11 Csl Behring Gmbh Fibrin adhesive granulate and method for its preparation
KR101865427B1 (ko) 2010-06-01 2018-06-07 백스터 인터내셔널 인코포레이티드 건성의 안정된 지혈 조성물의 제조 방법
KR101967085B1 (ko) 2010-06-01 2019-04-08 백스터 인터내셔널 인코포레이티드 건조 및 안정한 지혈 조성물의 제조 방법
US8940335B2 (en) 2010-06-01 2015-01-27 Baxter International Inc. Process for making dry and stable hemostatic compositions
RU2013155713A (ru) * 2011-07-06 2015-08-20 Профибрикс Бв Составы для лечения ран
IL242984A0 (en) 2015-12-08 2016-02-29 Omrix Biopharmaceuticals Ltd Thrombin microcapsules, their preparation and how to use them
US10159720B2 (en) * 2015-12-08 2018-12-25 Omrix Biopharmaceuticals Ltd Thrombin microcapsules, preparation and uses thereof
CN107754005B (zh) 2016-08-15 2021-06-15 广州倍绣生物技术有限公司 止血组合物及其制造方法

Also Published As

Publication number Publication date
WO2019133440A1 (en) 2019-07-04
JP2021508507A (ja) 2021-03-11
SG11202005231RA (en) 2020-07-29
EP3731885A1 (en) 2020-11-04
US20210379240A1 (en) 2021-12-09
CN111787958A (zh) 2020-10-16
EP3731885B1 (en) 2025-10-08
KR20200105680A (ko) 2020-09-08
AU2018396037A1 (en) 2020-06-18
MX2020006856A (es) 2020-08-24
US11583610B2 (en) 2023-02-21
BR112020011034A2 (pt) 2020-11-17

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20211118

EEER Examination request

Effective date: 20211118

EEER Examination request

Effective date: 20211118

EEER Examination request

Effective date: 20211118

FZDE Discontinued

Effective date: 20240405