CA3082352A1 - Multiple analyte ion source - Google Patents

Multiple analyte ion source Download PDF

Info

Publication number
CA3082352A1
CA3082352A1 CA3082352A CA3082352A CA3082352A1 CA 3082352 A1 CA3082352 A1 CA 3082352A1 CA 3082352 A CA3082352 A CA 3082352A CA 3082352 A CA3082352 A CA 3082352A CA 3082352 A1 CA3082352 A1 CA 3082352A1
Authority
CA
Canada
Prior art keywords
wells
analyte
sample
plate
substrate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3082352A
Other languages
English (en)
French (fr)
Inventor
Frenny KAUSHAL
Gholamreza Javahery
Lisa Cousins
Charles Jolliffe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PerkinElmer Health Sciences Canada Inc
Original Assignee
PerkinElmer Health Sciences Canada Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PerkinElmer Health Sciences Canada Inc filed Critical PerkinElmer Health Sciences Canada Inc
Publication of CA3082352A1 publication Critical patent/CA3082352A1/en
Pending legal-status Critical Current

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0422—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for gaseous samples
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0431—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0404—Capillaries used for transferring samples or ions
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0409—Sample holders or containers
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/10—Ion sources; Ion guns
    • H01J49/16—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
    • H01J49/165—Electrospray ionisation
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Plasma & Fusion (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)
CA3082352A 2017-11-10 2018-11-08 Multiple analyte ion source Pending CA3082352A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762584425P 2017-11-10 2017-11-10
US62/584,425 2017-11-10
PCT/IB2018/058793 WO2019092640A1 (en) 2017-11-10 2018-11-08 Multiple analyte ion source

Publications (1)

Publication Number Publication Date
CA3082352A1 true CA3082352A1 (en) 2019-05-16

Family

ID=66438268

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3082352A Pending CA3082352A1 (en) 2017-11-10 2018-11-08 Multiple analyte ion source

Country Status (6)

Country Link
US (1) US11367603B2 (https=)
EP (1) EP3707744A4 (https=)
JP (1) JP7293219B2 (https=)
CN (1) CN111566779A (https=)
CA (1) CA3082352A1 (https=)
WO (1) WO2019092640A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112309823B (zh) * 2020-11-13 2025-04-01 广州禾信仪器股份有限公司 质谱检测系统及离子源装置
US12555761B2 (en) * 2023-09-25 2026-02-17 Thermo Fisher Scientific (Bremen) Gmbh Sample probe systems and associated methods

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5872010A (en) * 1995-07-21 1999-02-16 Northeastern University Microscale fluid handling system
CA2357623A1 (en) * 1999-01-08 2000-07-13 Frantisek Foret Electro-pneumatic distributor for multiplexed .mu.-tas devices
WO2000066265A2 (en) * 1999-04-27 2000-11-09 Ciphergen Biosystems, Inc. Probes for a gas phase ion spectrometer
US20030224531A1 (en) * 2002-05-29 2003-12-04 Brennen Reid A. Microplate with an integrated microfluidic system for parallel processing minute volumes of fluids
SE0302074D0 (sv) * 2003-07-15 2003-07-15 Simon Ekstroem Device and method for analysis of samples using a combined sample treatment and sample carrier device
CA2507480A1 (en) * 2004-05-19 2005-11-19 Ionalytics Corporation Multiple nano-spray delivery system for faims
US20080087815A1 (en) * 2006-10-13 2008-04-17 Agilent Technologies, Inc. Time division multiplexing MS with beam converging capillary
CN104966659A (zh) * 2006-12-28 2015-10-07 东华理工学院 质谱仪离子源及原样样品中痕量成分的质谱分析方法
JP2011510302A (ja) * 2008-01-16 2011-03-31 シンジェンタ パーティシペーションズ アクチェンゲゼルシャフト 試料を質量分析するための装置、システム及び方法
US7659505B2 (en) * 2008-02-01 2010-02-09 Ionics Mass Spectrometry Group Inc. Ion source vessel and methods
US8217343B2 (en) * 2010-01-26 2012-07-10 Agilent Technologies, Inc. Device and method using microplasma array for ionizing samples for mass spectrometry
JP6757730B2 (ja) * 2014-12-31 2020-09-23 フリューダイム カナダ インコーポレイテッド マスサイトメトリーによる分析用の構造化生体試料

Also Published As

Publication number Publication date
US11367603B2 (en) 2022-06-21
US20200350150A1 (en) 2020-11-05
EP3707744A1 (en) 2020-09-16
JP2021502678A (ja) 2021-01-28
EP3707744A4 (en) 2021-08-11
CN111566779A (zh) 2020-08-21
JP7293219B2 (ja) 2023-06-19
WO2019092640A1 (en) 2019-05-16

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Effective date: 20220915