CA3080031C - Production method of thiazole derivative - Google Patents

Production method of thiazole derivative Download PDF

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Publication number
CA3080031C
CA3080031C CA3080031A CA3080031A CA3080031C CA 3080031 C CA3080031 C CA 3080031C CA 3080031 A CA3080031 A CA 3080031A CA 3080031 A CA3080031 A CA 3080031A CA 3080031 C CA3080031 C CA 3080031C
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Canada
Prior art keywords
compound
crystal
formula
production method
compound represented
Prior art date
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Application number
CA3080031A
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English (en)
French (fr)
Other versions
CA3080031A1 (en
Inventor
Takamasa Sugita
Arata Yanagisawa
Iwao Chujo
Masashi TAGA
Akihiro MIMURA
Atsushi Tada
Masashi Aoki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kyowa Kirin Co Ltd
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Kyowa Kirin Co Ltd
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Filing date
Publication date
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Publication of CA3080031A1 publication Critical patent/CA3080031A1/en
Application granted granted Critical
Publication of CA3080031C publication Critical patent/CA3080031C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CA3080031A 2015-01-09 2016-01-08 Production method of thiazole derivative Active CA3080031C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2015002964 2015-01-09
JP2015-002964 2015-01-09
CA2972746A CA2972746C (en) 2015-01-09 2016-01-08 Production method of thiazole derivative

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA2972746A Division CA2972746C (en) 2015-01-09 2016-01-08 Production method of thiazole derivative

Publications (2)

Publication Number Publication Date
CA3080031A1 CA3080031A1 (en) 2016-07-14
CA3080031C true CA3080031C (en) 2022-04-12

Family

ID=56356063

Family Applications (2)

Application Number Title Priority Date Filing Date
CA2972746A Active CA2972746C (en) 2015-01-09 2016-01-08 Production method of thiazole derivative
CA3080031A Active CA3080031C (en) 2015-01-09 2016-01-08 Production method of thiazole derivative

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CA2972746A Active CA2972746C (en) 2015-01-09 2016-01-08 Production method of thiazole derivative

Country Status (24)

Country Link
US (3) US10214523B2 (de)
EP (2) EP3822269A1 (de)
JP (2) JP6770962B2 (de)
CN (1) CN107108602B (de)
AR (1) AR103380A1 (de)
AU (1) AU2016205657B2 (de)
BR (1) BR112017014179A2 (de)
CA (2) CA2972746C (de)
CL (1) CL2017001695A1 (de)
CO (1) CO2017006204A2 (de)
DK (1) DK3242877T3 (de)
ES (1) ES2861050T3 (de)
HR (1) HRP20210385T1 (de)
HU (1) HUE053567T2 (de)
IL (2) IL252906B (de)
JO (2) JOP20200093A1 (de)
MX (2) MX2017009008A (de)
PL (1) PL3242877T3 (de)
PT (1) PT3242877T (de)
RS (1) RS61570B1 (de)
RU (2) RU2738937C2 (de)
SI (1) SI3242877T1 (de)
TW (2) TWI732748B (de)
WO (1) WO2016111381A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JOP20200093A1 (ar) * 2015-01-09 2017-06-16 Kyowa Kirin Co Ltd طريقة لإنتاج مشتق ثيازول
CN109293652B (zh) * 2017-07-24 2021-10-22 四川科伦博泰生物医药股份有限公司 一种取代的噻唑衍生物及其用途

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE445350B (sv) * 1978-04-14 1986-06-16 Roussel Uclaf Oximderivat av 3-azidometyl-7-amino-tiazolyl-acetamido-cefalosporansyra och dess anvendning som antibiotika
DK1700856T3 (en) * 2003-12-26 2015-12-14 Kyowa Hakko Kirin Co Ltd thiazole
CA2575411A1 (en) 2004-07-27 2006-02-02 Astellas Pharma Inc. Thiazole derivatives having vap-1 inhibitory activity
EP1894930A4 (de) 2005-06-23 2010-06-23 Kyowa Hakko Kirin Co Ltd Thiazolderivat
PT1921077T (pt) 2005-08-02 2017-10-26 Kyowa Hakko Kirin Co Ltd Agente para tratar e/ou prevenir distúrbio do sono
US7776870B2 (en) 2005-08-22 2010-08-17 Melior Pharmaceuticals I, Inc. Methods for modulating Lyn kinase activity and treating related disorders
CN101228143A (zh) * 2005-08-31 2008-07-23 安斯泰来制药株式会社 噻唑衍生物
KR20080040046A (ko) * 2005-08-31 2008-05-07 아스텔라스세이야쿠 가부시키가이샤 티아졸 유도체
TWI473614B (zh) 2008-05-29 2015-02-21 Kyowa Hakko Kirin Co Ltd Anti-analgesic inhibitors
EP2564871B1 (de) 2008-07-23 2017-11-15 Kyowa Hakko Kirin Co., Ltd. Therapeutisches Migränemittel
TWI548411B (zh) 2009-04-28 2016-09-11 Kyowa Hakko Kirin Co Ltd Exercise disorder treatment
UA110097C2 (uk) 2009-09-02 2015-11-25 Терапевтичний агент для лікування розладів настрою
UA113383C2 (xx) 2009-09-02 2017-01-25 Терапевтичний агент для лікування тривожних розладів
WO2012027965A1 (en) 2010-09-01 2012-03-08 Glaxo Group Limited Novel compounds
JP6266270B2 (ja) 2013-05-20 2018-01-24 セイコーインスツル株式会社 運動フォーム解析装置および運動フォーム解析方法
JOP20200093A1 (ar) * 2015-01-09 2017-06-16 Kyowa Kirin Co Ltd طريقة لإنتاج مشتق ثيازول

Also Published As

Publication number Publication date
JOP20200093A1 (ar) 2017-06-16
JO3546B1 (ar) 2020-07-05
TWI729810B (zh) 2021-06-01
EP3242877B1 (de) 2020-12-16
MX2021000711A (es) 2021-03-25
DK3242877T3 (da) 2021-03-08
CL2017001695A1 (es) 2018-03-23
US10894790B2 (en) 2021-01-19
CA2972746C (en) 2020-07-07
EP3242877A1 (de) 2017-11-15
CA3080031A1 (en) 2016-07-14
JP2020193209A (ja) 2020-12-03
CO2017006204A2 (es) 2017-11-10
PT3242877T (pt) 2021-03-11
TWI732748B (zh) 2021-07-11
CA2972746A1 (en) 2016-07-14
JP6770962B2 (ja) 2020-10-21
IL272811A (en) 2020-04-30
RS61570B1 (sr) 2021-04-29
RU2020141085A (ru) 2021-02-10
CN107108602B (zh) 2021-08-03
IL252906B (en) 2020-03-31
TW201639835A (zh) 2016-11-16
US20200216438A1 (en) 2020-07-09
RU2017128217A3 (de) 2019-02-11
US10214523B2 (en) 2019-02-26
RU2017128217A (ru) 2019-02-11
US20190144438A1 (en) 2019-05-16
EP3242877A4 (de) 2018-10-17
MX2017009008A (es) 2017-09-27
BR112017014179A2 (pt) 2018-03-06
WO2016111381A1 (en) 2016-07-14
US10618894B2 (en) 2020-04-14
PL3242877T3 (pl) 2021-05-31
JP7068402B2 (ja) 2022-05-16
IL252906A0 (en) 2017-08-31
TW202035397A (zh) 2020-10-01
AU2016205657B2 (en) 2019-01-17
AR103380A1 (es) 2017-05-03
RU2738937C2 (ru) 2020-12-18
US20180002326A1 (en) 2018-01-04
JP2018501282A (ja) 2018-01-18
SI3242877T1 (sl) 2021-04-30
EP3822269A1 (de) 2021-05-19
HUE053567T2 (hu) 2021-07-28
HRP20210385T1 (hr) 2021-04-16
AU2016205657A1 (en) 2017-07-13
ES2861050T3 (es) 2021-10-05
CN107108602A (zh) 2017-08-29

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