CA3066689C - Traitement de maladies inflammatoires par des inhibiteurs de l'activite de c5a - Google Patents
Traitement de maladies inflammatoires par des inhibiteurs de l'activite de c5a Download PDFInfo
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- CA3066689C CA3066689C CA3066689A CA3066689A CA3066689C CA 3066689 C CA3066689 C CA 3066689C CA 3066689 A CA3066689 A CA 3066689A CA 3066689 A CA3066689 A CA 3066689A CA 3066689 C CA3066689 C CA 3066689C
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- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
Abstract
La présente invention concerne des inhibiteurs de l'activité de C5a et leur utilisation dans le traitement de maladies cutanées, neutrophiles, inflammatoires chez un sujet.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP17177657.8 | 2017-06-23 | ||
EP17177657 | 2017-06-23 | ||
EP17189938 | 2017-09-07 | ||
EP17189938.8 | 2017-09-07 | ||
PCT/EP2018/065676 WO2018234118A1 (fr) | 2017-06-23 | 2018-06-13 | Traitement de maladies inflammatoires par des inhibiteurs de l'activité de c5a |
Publications (2)
Publication Number | Publication Date |
---|---|
CA3066689A1 CA3066689A1 (fr) | 2018-12-27 |
CA3066689C true CA3066689C (fr) | 2024-01-16 |
Family
ID=62636193
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA3066689A Active CA3066689C (fr) | 2017-06-23 | 2018-06-13 | Traitement de maladies inflammatoires par des inhibiteurs de l'activite de c5a |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP3642230A1 (fr) |
JP (1) | JP2020524696A (fr) |
KR (1) | KR20200020727A (fr) |
CN (1) | CN111201241A (fr) |
AU (1) | AU2018286754A1 (fr) |
CA (1) | CA3066689C (fr) |
IL (1) | IL271074A (fr) |
SG (1) | SG11201912882QA (fr) |
TW (1) | TWI786132B (fr) |
WO (1) | WO2018234118A1 (fr) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2017218515A1 (fr) | 2016-06-14 | 2017-12-21 | Regeneron Pharmaceuticals, Inc. | Anticorps anti-c5 et leurs utilisations |
CA3083113A1 (fr) | 2017-12-13 | 2019-06-20 | Regeneron Pharmaceuticals, Inc. | Associations d'anticorps anti-c5 et utilisations associees |
CA3132771A1 (fr) * | 2019-03-14 | 2020-09-17 | Morphosys Ag | Anticorps ciblant c5ar |
TW202140553A (zh) * | 2020-01-13 | 2021-11-01 | 美商威特拉公司 | C5ar1抗體分子及其用途 |
CA3183886A1 (fr) * | 2020-06-24 | 2021-12-30 | Pingxia ZHU | Anticorps reconnaissant de maniere specifique c5a et leurs utilisations |
KR20230142831A (ko) | 2021-01-13 | 2023-10-11 | 비스테라, 인크. | 인간화된 보체 5a 수용체 1 항체 및 이의 사용 방법 |
Family Cites Families (24)
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US4704355A (en) | 1985-03-27 | 1987-11-03 | New Horizons Diagnostics Corporation | Assay utilizing ATP encapsulated within liposome particles |
CA2025907A1 (fr) | 1989-09-21 | 1991-03-22 | Franklin D. Collins | Methode pour le transport de composes a travers la barriere hemato-encephalique |
EP1690935A3 (fr) | 1990-01-12 | 2008-07-30 | Abgenix, Inc. | Génération d'anticorps xenogéniques |
AUPO755097A0 (en) | 1997-06-25 | 1997-07-17 | University Of Queensland, The | Receptor agonist and antagonist |
US7754208B2 (en) | 2001-01-17 | 2010-07-13 | Trubion Pharmaceuticals, Inc. | Binding domain-immunoglobulin fusion proteins |
US20030133939A1 (en) | 2001-01-17 | 2003-07-17 | Genecraft, Inc. | Binding domain-immunoglobulin fusion proteins |
AUPR833401A0 (en) * | 2001-10-17 | 2001-11-08 | University Of Queensland, The | G protein-coupled receptor antagonists |
HUE038239T2 (hu) | 2004-02-12 | 2018-10-29 | Archemix Llc | Komplementrendszerrel összefüggõ rendellenességek kezelésében alkalmazható aptamer terapeutikumok |
CN1997384A (zh) * | 2004-03-26 | 2007-07-11 | 普罗米克斯有限公司 | 使用补体C5a受体调节剂治疗神经系统病症 |
EP2049141A4 (fr) * | 2006-07-21 | 2011-10-26 | Promics Pty Ltd | Traitement de l'hyperplasie intimale et d'affections associées |
GB0617734D0 (en) | 2006-09-08 | 2006-10-18 | Evolutec Ltd | Method of treating peripheral nerve disorders |
EP3078658B1 (fr) * | 2008-12-22 | 2019-04-10 | ChemoCentryx, Inc. | Antagonistes de c5ar |
GB0905790D0 (en) * | 2009-04-03 | 2009-05-20 | Alligator Bioscience Ab | Novel polypeptides and use thereof |
EP2327725A1 (fr) | 2009-11-26 | 2011-06-01 | InflaRx GmbH | Groupes caractéristiques à liaison anti-C5a avec une activité à blocage élevé |
DK2585064T3 (en) | 2010-06-24 | 2017-07-24 | Chemocentryx Inc | C5aR antagonists |
MX366660B (es) * | 2013-03-14 | 2019-07-18 | Alnylam Pharmaceuticals Inc | Composiciones de arni contra el componente c5 del complemento y métodos para su uso. |
CN105392803B (zh) * | 2013-05-08 | 2019-12-06 | 诺和诺德股份有限公司 | C5aR拮抗剂的用途 |
BR112016021629A2 (pt) | 2014-03-20 | 2018-07-10 | Inflarx Gmbh | inibidores de c5a para o tratamento de pneumonia viral |
WO2016044419A1 (fr) | 2014-09-16 | 2016-03-24 | Alnylam Pharmaceuticals, Inc. | Compositions d'arni de composant du complément c5 et leurs procédés d'utilisation |
ES2719876T3 (es) | 2014-10-15 | 2019-07-16 | Alexion Pharma Inc | Métodos para replicar un cultivo celular de producción de eculizumab a gran escala |
FR3030515B1 (fr) * | 2014-12-23 | 2017-01-20 | Galderma Res & Dev | Nouveaux composes antagonistes des recepteurs cxcr1 et cxcr2 aux chimiokines, et leur utilisation dans le traitement de pathologies mediees par des chimiokines |
WO2016209956A1 (fr) | 2015-06-26 | 2016-12-29 | Alexion Pharmaceuticals, Inc. | Procédé de traitement d'un patient soumis à une vaccination avec l'éculizumab ou un variant de l'éculizumab |
MA44629A (fr) | 2016-04-04 | 2021-03-24 | Chemocentryx Inc | Antagonistes de c5ar solubles |
TW202348249A (zh) * | 2017-04-03 | 2023-12-16 | 德商因夫萊亞斯有限公司 | 使用c5a活性抑制劑於發炎性疾病之治療 |
-
2018
- 2018-06-13 KR KR1020197038211A patent/KR20200020727A/ko not_active Application Discontinuation
- 2018-06-13 TW TW107120362A patent/TWI786132B/zh active
- 2018-06-13 CN CN201880041303.4A patent/CN111201241A/zh active Pending
- 2018-06-13 SG SG11201912882QA patent/SG11201912882QA/en unknown
- 2018-06-13 CA CA3066689A patent/CA3066689C/fr active Active
- 2018-06-13 WO PCT/EP2018/065676 patent/WO2018234118A1/fr unknown
- 2018-06-13 JP JP2019570986A patent/JP2020524696A/ja active Pending
- 2018-06-13 AU AU2018286754A patent/AU2018286754A1/en active Pending
- 2018-06-13 EP EP18732016.3A patent/EP3642230A1/fr active Pending
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2019
- 2019-12-01 IL IL271074A patent/IL271074A/en unknown
Also Published As
Publication number | Publication date |
---|---|
KR20200020727A (ko) | 2020-02-26 |
TWI786132B (zh) | 2022-12-11 |
TW201904611A (zh) | 2019-02-01 |
WO2018234118A1 (fr) | 2018-12-27 |
CN111201241A (zh) | 2020-05-26 |
IL271074A (en) | 2020-01-30 |
SG11201912882QA (en) | 2020-01-30 |
CA3066689A1 (fr) | 2018-12-27 |
JP2020524696A (ja) | 2020-08-20 |
AU2018286754A1 (en) | 2019-12-19 |
EP3642230A1 (fr) | 2020-04-29 |
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