CA3045024A1 - Natural combination hormone replacement formulations and therapies - Google Patents
Natural combination hormone replacement formulations and therapies Download PDFInfo
- Publication number
- CA3045024A1 CA3045024A1 CA3045024A CA3045024A CA3045024A1 CA 3045024 A1 CA3045024 A1 CA 3045024A1 CA 3045024 A CA3045024 A CA 3045024A CA 3045024 A CA3045024 A CA 3045024A CA 3045024 A1 CA3045024 A1 CA 3045024A1
- Authority
- CA
- Canada
- Prior art keywords
- estradiol
- progesterone
- subject
- auc
- estrone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
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- Chemical & Material Sciences (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
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| US62/481,060 | 2017-04-03 | ||
| PCT/US2017/064788 WO2018136161A1 (en) | 2016-12-05 | 2017-12-05 | Natural combination hormone replacement formulations and therapies |
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| KR (1) | KR20200018383A (ja) |
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| CA (1) | CA3045024A1 (ja) |
| IL (1) | IL267023A (ja) |
| MX (1) | MX2019006513A (ja) |
| RU (1) | RU2019115913A (ja) |
| WO (1) | WO2018136161A1 (ja) |
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| US20220105107A1 (en) * | 2020-10-01 | 2022-04-07 | Michael Liguori | Bioidentical progesterone cream infused with nanoemulsified cbd |
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| US5208225A (en) * | 1986-02-27 | 1993-05-04 | Warner-Lambert Company | Compositions containing fixed combinations |
| US20020132801A1 (en) * | 2001-01-11 | 2002-09-19 | Schering Aktiengesellschaft | Drospirenone for hormone replacement therapy |
| US6901278B1 (en) * | 2002-01-29 | 2005-05-31 | Morris Notelovitz | Methods for reducing the risk of breast cancer in and improving the health of women |
| US20040062794A1 (en) * | 2002-09-30 | 2004-04-01 | Lee Shulman | 17Beta- estradiol/levonorgestrel transdermal patch for hormone replacement therapy |
| US9301920B2 (en) * | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| JP2017516768A (ja) * | 2014-05-22 | 2017-06-22 | セラピューティックスエムディー インコーポレーテッドＴｈｅｒａｐｅｕｔｉｃｓｍｄ， Ｉｎｃ． | 天然の併用ホルモン補充療法剤及び療法 |
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| US20220105107A1 (en) * | 2020-10-01 | 2022-04-07 | Michael Liguori | Bioidentical progesterone cream infused with nanoemulsified cbd |
Also Published As
| Publication number | Publication date |
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| RU2019115913A (ru) | 2021-01-15 |
| RU2019115913A3 (ja) | 2021-03-19 |
| EP3548036A4 (en) | 2020-06-17 |
| MX2019006513A (es) | 2019-08-14 |
| BR112019011655A2 (pt) | 2019-10-22 |
| JP2020504093A (ja) | 2020-02-06 |
| WO2018136161A9 (en) | 2019-08-22 |
| WO2018136161A1 (en) | 2018-07-26 |
| IL267023A (en) | 2019-07-31 |
| EP3548036A1 (en) | 2019-10-09 |
| KR20200018383A (ko) | 2020-02-19 |
| AU2017394679A1 (en) | 2019-06-13 |
| CN110290793A (zh) | 2019-09-27 |
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| Date | Code | Title | Description |
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| FZDE | Discontinued |
Effective date: 20240318 |