CA3034470A1 - Avibactam free acid - Google Patents
Avibactam free acid Download PDFInfo
- Publication number
- CA3034470A1 CA3034470A1 CA3034470A CA3034470A CA3034470A1 CA 3034470 A1 CA3034470 A1 CA 3034470A1 CA 3034470 A CA3034470 A CA 3034470A CA 3034470 A CA3034470 A CA 3034470A CA 3034470 A1 CA3034470 A1 CA 3034470A1
- Authority
- CA
- Canada
- Prior art keywords
- avibactam
- formula
- oxo
- diazabicylco
- octan
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16185913.7 | 2016-08-26 | ||
| EP16185913 | 2016-08-26 | ||
| PCT/EP2017/071471 WO2018037124A1 (en) | 2016-08-26 | 2017-08-25 | Avibactam free acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3034470A1 true CA3034470A1 (en) | 2018-03-01 |
Family
ID=56802364
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3034470A Abandoned CA3034470A1 (en) | 2016-08-26 | 2017-08-25 | Avibactam free acid |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US11124513B2 (https=) |
| EP (1) | EP3504207B1 (https=) |
| JP (1) | JP7183147B2 (https=) |
| KR (1) | KR102482826B1 (https=) |
| CN (1) | CN109641901B (https=) |
| AU (1) | AU2017315164B2 (https=) |
| CA (1) | CA3034470A1 (https=) |
| WO (1) | WO2018037124A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3580221B1 (en) | 2017-02-08 | 2020-12-16 | Sandoz AG | Process for the preparation of crystalline form c of avibactam sodium |
| CN113105455B (zh) * | 2020-01-10 | 2024-05-17 | 四川科伦药物研究院有限公司 | 晶型b阿维巴坦钠的制备方法 |
| CN115677697B (zh) * | 2022-09-19 | 2024-08-06 | 瑞阳制药股份有限公司 | 粒度可调控且流动性好的b晶型阿维巴坦钠析晶方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2812635B1 (fr) | 2000-08-01 | 2002-10-11 | Aventis Pharma Sa | Nouveaux composes heterocycliques, preparation et utilisation comme medicaments notamment comme anti- bacteriens |
| FR2951171A1 (fr) * | 2009-10-09 | 2011-04-15 | Novexel | Nouveau sel de sodium d'un compose azabicyclique sous forme enantiomere cristallisee et nouvelles formes polymorphes et pseudopolymorphes ainsi que leur preparation |
| RU2610091C2 (ru) | 2011-06-17 | 2017-02-07 | Астразенека Аб | (2S,5R)-5-[(бензилокси)амино]пиперидин-2-карбоксамид |
| US9567335B2 (en) | 2013-03-08 | 2017-02-14 | Wockhardt Limited | Process for sodium salt of (2S, 5R)-2-carboxamido-7-oxo-6-sulfooxy -1,6-diaza-bicyclo[3.2.1]octane |
| WO2016046845A1 (en) * | 2014-09-25 | 2016-03-31 | Manu Chaudhary | Stealth, targeted nanoparticles (stn) for oral drug delivery |
| US10265326B2 (en) | 2015-08-10 | 2019-04-23 | Sandoz Ag | Form C of avibactam sodium |
| CN106699756B (zh) * | 2016-12-30 | 2019-10-29 | 淄博鑫泉医药技术服务有限公司 | β内酰胺酶抑制剂阿维巴坦的合成方法 |
-
2017
- 2017-08-25 EP EP17758148.5A patent/EP3504207B1/en active Active
- 2017-08-25 CA CA3034470A patent/CA3034470A1/en not_active Abandoned
- 2017-08-25 WO PCT/EP2017/071471 patent/WO2018037124A1/en not_active Ceased
- 2017-08-25 CN CN201780052135.4A patent/CN109641901B/zh active Active
- 2017-08-25 US US16/328,117 patent/US11124513B2/en active Active
- 2017-08-25 KR KR1020197008169A patent/KR102482826B1/ko active Active
- 2017-08-25 AU AU2017315164A patent/AU2017315164B2/en active Active
- 2017-08-25 JP JP2019508812A patent/JP7183147B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| AU2017315164A1 (en) | 2019-02-28 |
| US20190185473A1 (en) | 2019-06-20 |
| KR20190040988A (ko) | 2019-04-19 |
| CN109641901B (zh) | 2022-12-09 |
| KR102482826B1 (ko) | 2022-12-28 |
| EP3504207B1 (en) | 2022-06-01 |
| EP3504207A1 (en) | 2019-07-03 |
| AU2017315164B2 (en) | 2021-12-09 |
| US11124513B2 (en) | 2021-09-21 |
| JP2019524829A (ja) | 2019-09-05 |
| CN109641901A (zh) | 2019-04-16 |
| WO2018037124A1 (en) | 2018-03-01 |
| JP7183147B2 (ja) | 2022-12-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |
Effective date: 20230227 |