CA3025217A1 - Antibodies, composition and kits comprising same, and methods of use thereof - Google Patents
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- CA3025217A1 CA3025217A1 CA3025217A CA3025217A CA3025217A1 CA 3025217 A1 CA3025217 A1 CA 3025217A1 CA 3025217 A CA3025217 A CA 3025217A CA 3025217 A CA3025217 A CA 3025217A CA 3025217 A1 CA3025217 A1 CA 3025217A1
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/567—Framework region [FR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
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- Neurology (AREA)
- Communicable Diseases (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Emergency Medicine (AREA)
- Physical Education & Sports Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNPCT/CN2016/083653 | 2016-05-27 | ||
| PCT/CN2016/083653 WO2017201731A1 (en) | 2016-05-27 | 2016-05-27 | Antibodies, composition and kits comprising same, and methods of use thereof |
| PCT/CN2017/086280 WO2017202387A1 (en) | 2016-05-27 | 2017-05-27 | Antibodies, composition and kits comprising same, and methods of use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3025217A1 true CA3025217A1 (en) | 2017-11-30 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3025217A Pending CA3025217A1 (en) | 2016-05-27 | 2017-05-27 | Antibodies, composition and kits comprising same, and methods of use thereof |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11192946B2 (enExample) |
| EP (1) | EP3464346A4 (enExample) |
| JP (1) | JP7210026B2 (enExample) |
| KR (1) | KR102540512B1 (enExample) |
| CN (1) | CN109563155B (enExample) |
| AU (1) | AU2017269526B2 (enExample) |
| CA (1) | CA3025217A1 (enExample) |
| WO (2) | WO2017201731A1 (enExample) |
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| WO2017201731A1 (en) | 2016-05-27 | 2017-11-30 | Beijing Vdjbio Co., Ltd. | Antibodies, composition and kits comprising same, and methods of use thereof |
| CA3083971A1 (en) * | 2017-11-30 | 2019-06-06 | Bio-Thera Solutions, Ltd. | Liquid formulation of humanized antibody for treating il-6 related diseases |
| WO2019178259A2 (en) | 2018-03-14 | 2019-09-19 | Celledit Llc | Modification of immune cells for reducing toxicity and uses thereof in adoptive cell therapy |
| AU2019286396A1 (en) | 2018-06-14 | 2020-12-17 | Bioatla, Inc. | Multi-specific antibody constructs |
| EP3908303A4 (en) * | 2019-01-07 | 2023-05-03 | Hunan Siweikang Therapeutics Co. Ltd | MODIFIED IMMUNE CELLS CO-EXPRESSING A CHIMERIC ANTIGEN RECEPTOR AND AN IL-6 ANTAGONIST TO REDUCE TOXICITY, AND USES THEREOF IN ADOPTIVE CELL THERAPY |
| WO2020176478A1 (en) | 2019-02-25 | 2020-09-03 | The University Of Chicago | Methods and compositions for treating inflammatory and autoimmune conditions with ecm-affinity peptides linked to anti-inflammatory agents |
| US20220233710A1 (en) * | 2019-05-20 | 2022-07-28 | Nantong Yichen Biopharma. Co. Ltd. | Bispecific molecule and preparation and use thereof |
| CN111588850A (zh) * | 2020-02-19 | 2020-08-28 | 中国科学技术大学 | Il-6受体抗体的新用途 |
| CN116261448A (zh) * | 2020-08-19 | 2023-06-13 | 百奥泰生物制药股份有限公司 | 用于治疗il-6相关疾病的包含高浓度人源化抗体的液体制剂 |
| CN118632873A (zh) * | 2022-11-07 | 2024-09-10 | 北京伟德杰生物科技有限公司 | 双特异性抗体及其应用 |
| WO2024098939A1 (zh) * | 2022-11-07 | 2024-05-16 | 北京伟德杰生物科技有限公司 | 双功能融合蛋白及其应用 |
| CN120818056A (zh) * | 2024-04-15 | 2025-10-21 | 北京伟德杰生物科技有限公司 | 抗白介素6受体的抗体及其应用 |
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| WO2005090405A1 (ja) | 2004-03-24 | 2005-09-29 | Chugai Seiyaku Kabushiki Kaisha | インターロイキン－６受容体に対するヒト型化抗体のサブタイプ |
| EP2006381B1 (en) | 2006-03-31 | 2016-02-03 | Chugai Seiyaku Kabushiki Kaisha | Method for controlling blood pharmacokinetics of antibodies |
| NZ573557A (en) | 2006-06-02 | 2010-08-27 | Regeneron Pharma | High affinity antibodies to human il-6 receptor |
| RU2505603C2 (ru) * | 2007-09-26 | 2014-01-27 | Чугаи Сейяку Кабусики Кайся | Антитело против рецептора il-6 |
| CA2700701C (en) * | 2007-09-26 | 2020-12-29 | Chugai Seiyaku Kabushiki Kaisha | Method of modifying isoelectric point of antibody via amino acid substitution in cdr |
| TWI440469B (zh) * | 2008-09-26 | 2014-06-11 | Chugai Pharmaceutical Co Ltd | Improved antibody molecules |
| JP6097702B2 (ja) * | 2011-03-03 | 2017-03-15 | アペクシジェン， インコーポレイテッド | 抗ｉｌ−６受容体抗体およびその使用方法 |
| US9487590B2 (en) * | 2012-09-25 | 2016-11-08 | Cytomx Therapeutics, Inc. | Activatable antibodies that bind interleukin-6 receptor and methods of use thereof |
| WO2017201731A1 (en) | 2016-05-27 | 2017-11-30 | Beijing Vdjbio Co., Ltd. | Antibodies, composition and kits comprising same, and methods of use thereof |
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2016
- 2016-05-27 WO PCT/CN2016/083653 patent/WO2017201731A1/en not_active Ceased
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2017
- 2017-05-27 KR KR1020187037865A patent/KR102540512B1/ko active Active
- 2017-05-27 EP EP17802233.1A patent/EP3464346A4/en active Pending
- 2017-05-27 AU AU2017269526A patent/AU2017269526B2/en active Active
- 2017-05-27 JP JP2019514173A patent/JP7210026B2/ja active Active
- 2017-05-27 CN CN201780046893.5A patent/CN109563155B/zh active Active
- 2017-05-27 WO PCT/CN2017/086280 patent/WO2017202387A1/en not_active Ceased
- 2017-05-27 CA CA3025217A patent/CA3025217A1/en active Pending
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2018
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2021
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| Publication number | Publication date |
|---|---|
| KR102540512B1 (ko) | 2023-06-05 |
| EP3464346A4 (en) | 2020-01-22 |
| KR20190015380A (ko) | 2019-02-13 |
| US20220195032A1 (en) | 2022-06-23 |
| EP3464346A1 (en) | 2019-04-10 |
| JP2019523653A (ja) | 2019-08-29 |
| US12006362B2 (en) | 2024-06-11 |
| WO2017202387A1 (en) | 2017-11-30 |
| US20190315854A1 (en) | 2019-10-17 |
| WO2017201731A1 (en) | 2017-11-30 |
| CN109563155A (zh) | 2019-04-02 |
| US11192946B2 (en) | 2021-12-07 |
| AU2017269526B2 (en) | 2021-08-12 |
| AU2017269526A1 (en) | 2018-12-13 |
| JP7210026B2 (ja) | 2023-01-23 |
| CN109563155B (zh) | 2023-04-11 |
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