CA3021021A1 - Combinations for the treatment of neoplasms using quiescent cell targeting and egfr inhibitors - Google Patents
Combinations for the treatment of neoplasms using quiescent cell targeting and egfr inhibitors Download PDFInfo
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- CA3021021A1 CA3021021A1 CA3021021A CA3021021A CA3021021A1 CA 3021021 A1 CA3021021 A1 CA 3021021A1 CA 3021021 A CA3021021 A CA 3021021A CA 3021021 A CA3021021 A CA 3021021A CA 3021021 A1 CA3021021 A1 CA 3021021A1
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- cancer
- egfr tki
- neoplasm
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Classifications
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
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- A—HUMAN NECESSITIES
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
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- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P35/04—Antineoplastic agents specific for metastasis
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Landscapes
- Health & Medical Sciences (AREA)
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- Veterinary Medicine (AREA)
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- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
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- Oncology (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US201662323537P | 2016-04-15 | 2016-04-15 | |
| US62/323,537 | 2016-04-15 | ||
| PCT/US2017/027719 WO2017181075A1 (en) | 2016-04-15 | 2017-04-14 | Combinations for the treatment of neoplasms using quiescent cell targeting and egfr inhibitors |
Publications (1)
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| CA3021021A1 true CA3021021A1 (en) | 2017-10-19 |
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| CA3021021A Pending CA3021021A1 (en) | 2016-04-15 | 2017-04-14 | Combinations for the treatment of neoplasms using quiescent cell targeting and egfr inhibitors |
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| EP (1) | EP3442505A4 (enExample) |
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| MX (2) | MX2018012511A (enExample) |
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| CA3009350A1 (en) * | 2016-01-05 | 2017-07-13 | The Trustees Of Columbia University In The City Of New York | Compositions and methods for regulating activity of inhibitor of dna binding-2 (id2) protein |
| US10322128B2 (en) | 2016-04-15 | 2019-06-18 | Felicitex Therapeutics, Inc. | Combinations for the treatment of neoplasms using quiescent cell targeting with EGFR inhibitors |
| CN109313197A (zh) | 2016-04-15 | 2019-02-05 | 费利克斯疗法公司 | 使用静止细胞靶向和有丝分裂抑制剂的用于治疗肿瘤的组合 |
| CN113557237B (zh) | 2019-01-18 | 2025-01-14 | 沃若诺伊公司 | 吡咯并吡啶衍生物及其预防或治疗蛋白激酶相关疾病的用途 |
| WO2020235973A1 (ko) * | 2019-05-22 | 2020-11-26 | 주식회사 보로노이 | 암의 예방 및/또는 치료를 위한 피롤로-피리딘 유도체 화합물의 신규 용도 |
| KR20220081631A (ko) | 2020-12-09 | 2022-06-16 | 보로노이 주식회사 | 염증성 질환의 예방 및/또는 치료를 위한 피롤로-피리딘 유도체 화합물의 신규 용도 |
| JP2024523861A (ja) * | 2021-06-15 | 2024-07-02 | ジェネンテック， インコーポレイテッド | がんを処置するための併用療法におけるｅｇｆｒ阻害剤およびｐｅｒｋ活性化剤、ならびにこれらの使用 |
| AU2022426699A1 (en) | 2021-12-30 | 2024-07-11 | Biomea Fusion, Inc. | Pyrazine compounds as inhibitors of flt3 |
| CN115947673B (zh) * | 2022-12-19 | 2024-03-15 | 湖南岳靶生物医药有限公司 | 一种化疗药物增敏剂、组合物及其应用 |
| CN116212030A (zh) * | 2023-03-03 | 2023-06-06 | 河南真实生物科技有限公司 | 包含阿兹夫定的抗肿瘤药物组合物 |
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| EP2560004A1 (de) * | 2011-08-19 | 2013-02-20 | DST Diagnostische Systeme & Technologien GmbH | Neues PoC-Testsystem und Verfahren |
| US9446044B2 (en) * | 2011-08-19 | 2016-09-20 | Diaxonhit | DYRK1 inhibitors and uses thereof |
| RU2016117729A (ru) | 2012-10-10 | 2017-11-10 | Фелиситекс Терапеутикс, Инк. | Терапия рака путем таргетинга покоящихся раковых клеток |
| CA2854542A1 (en) * | 2013-06-18 | 2014-12-18 | 4Sc Discovery Gmbh | Method of inhibiting dyrk1b |
| MA39763A (fr) * | 2014-03-20 | 2017-01-25 | Samumed Llc | Indazole-3-carboxamides 5-substitués, et préparation et utilisation de ceux-ci |
| EP3191523B1 (en) | 2014-09-08 | 2019-08-07 | Yeda Research and Development Co., Ltd. | Compositions and methods for treating cancer resistant to a tyrosine kinase inhibitor (tki) |
| US20170304313A1 (en) * | 2014-10-06 | 2017-10-26 | Novartis Ag | Therapeutic Combination For The Treatment Of Cancer |
| CN108135871B (zh) | 2015-07-23 | 2022-11-04 | 博蔚医药生物科技股份有限公司 | 阻断疾病的泛素化-蛋白酶体系统的胺萘醌化合物及医药组合物 |
| US10322128B2 (en) * | 2016-04-15 | 2019-06-18 | Felicitex Therapeutics, Inc. | Combinations for the treatment of neoplasms using quiescent cell targeting with EGFR inhibitors |
| CN109313197A (zh) | 2016-04-15 | 2019-02-05 | 费利克斯疗法公司 | 使用静止细胞靶向和有丝分裂抑制剂的用于治疗肿瘤的组合 |
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2018
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| JP7123806B2 (ja) | 2022-08-23 |
| IL288777A (en) | 2022-02-01 |
| KR102494174B1 (ko) | 2023-02-02 |
| JP2019511554A (ja) | 2019-04-25 |
| IL262323B (en) | 2022-03-01 |
| US20190298723A1 (en) | 2019-10-03 |
| JP2022145800A (ja) | 2022-10-04 |
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| US20170296541A1 (en) | 2017-10-19 |
| EP3442505A1 (en) | 2019-02-20 |
| US10322128B2 (en) | 2019-06-18 |
| EP3442505A4 (en) | 2019-12-18 |
| AU2023200428A1 (en) | 2023-03-02 |
| WO2017181075A1 (en) | 2017-10-19 |
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