MX2018012511A - Combinaciones para el tratamiento de neoplasias usando localizacion de celulas quiescentes e inhibidores de egfr. - Google Patents
Combinaciones para el tratamiento de neoplasias usando localizacion de celulas quiescentes e inhibidores de egfr.Info
- Publication number
- MX2018012511A MX2018012511A MX2018012511A MX2018012511A MX2018012511A MX 2018012511 A MX2018012511 A MX 2018012511A MX 2018012511 A MX2018012511 A MX 2018012511A MX 2018012511 A MX2018012511 A MX 2018012511A MX 2018012511 A MX2018012511 A MX 2018012511A
- Authority
- MX
- Mexico
- Prior art keywords
- treatment
- neoplasms
- combinations
- cell targeting
- egfr inhibitors
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente invención proporciona composiciones y métodos para el tratamiento de neoplasias, en particular, mediante la localización de células cancerosas en estado quiescente, o en reposo, con agentes terapéuticos en combinación con otros tratamientos eficaces contra ciertas afecciones neoplásicas, en particular, tratamiento anticanceroso con agentes inhibidores de EGFR.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201662323537P | 2016-04-15 | 2016-04-15 | |
PCT/US2017/027719 WO2017181075A1 (en) | 2016-04-15 | 2017-04-14 | Combinations for the treatment of neoplasms using quiescent cell targeting and egfr inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2018012511A true MX2018012511A (es) | 2019-07-08 |
Family
ID=60039950
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2018012511A MX2018012511A (es) | 2016-04-15 | 2017-04-14 | Combinaciones para el tratamiento de neoplasias usando localizacion de celulas quiescentes e inhibidores de egfr. |
MX2023000549A MX2023000549A (es) | 2016-04-15 | 2018-10-12 | Combinaciones para el tratamiento de neoplasias usando localizacion de celulas quiescentes e inhibidores de egfr. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2023000549A MX2023000549A (es) | 2016-04-15 | 2018-10-12 | Combinaciones para el tratamiento de neoplasias usando localizacion de celulas quiescentes e inhibidores de egfr. |
Country Status (11)
Country | Link |
---|---|
US (3) | US10322128B2 (es) |
EP (1) | EP3442505A4 (es) |
JP (2) | JP7123806B2 (es) |
KR (2) | KR102494174B1 (es) |
CN (1) | CN109562176A (es) |
AU (2) | AU2017248762A1 (es) |
BR (1) | BR112018071031A2 (es) |
CA (1) | CA3021021A1 (es) |
IL (2) | IL262323B (es) |
MX (2) | MX2018012511A (es) |
WO (1) | WO2017181075A1 (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP4349410A3 (en) * | 2016-01-05 | 2024-06-05 | The Trustees Of Columbia University In The City Of New York | A composition for use in the therapeutic treatment of a cancer or a tumor |
KR102494174B1 (ko) * | 2016-04-15 | 2023-02-02 | 펠리시텍스 쎄라퓨틱스, 인코포레이티드 | 정지 세포 표적화 및 egfr 억제제를 이용하는 신생물 치료를 위한 조합 |
US10314843B2 (en) | 2016-04-15 | 2019-06-11 | Felicitex Therapeutics, Inc. | Combinations for the treatment of neoplasms using quiescent cell targeting and inhibitors of mitosis |
JP2022534881A (ja) * | 2019-05-22 | 2022-08-04 | ボロノイ・カンパニー・リミテッド | がんの予防および/または処置のためのピロロ-ピリジン誘導体化合物の新規な使用 |
JP2024523861A (ja) * | 2021-06-15 | 2024-07-02 | ジェネンテック, インコーポレイテッド | がんを処置するための併用療法におけるegfr阻害剤およびperk活性化剤、ならびにこれらの使用 |
WO2023129667A1 (en) | 2021-12-30 | 2023-07-06 | Biomea Fusion, Inc. | Pyrazine compounds as inhibitors of flt3 |
CN115947673B (zh) * | 2022-12-19 | 2024-03-15 | 湖南岳靶生物医药有限公司 | 一种化疗药物增敏剂、组合物及其应用 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT2744797E (pt) | 2011-08-19 | 2015-11-16 | Diaxonhit | Inibidores de dyrkl e suas utilizações |
EP2560004A1 (de) * | 2011-08-19 | 2013-02-20 | DST Diagnostische Systeme & Technologien GmbH | Neues PoC-Testsystem und Verfahren |
JP2015534584A (ja) | 2012-10-10 | 2015-12-03 | フェリシテックス・セラピューティクス,インコーポレイテッド | 静止癌細胞の標的化による癌の治療 |
CA2854542A1 (en) * | 2013-06-18 | 2014-12-18 | 4Sc Discovery Gmbh | Method of inhibiting dyrk1b |
WO2015143380A1 (en) | 2014-03-20 | 2015-09-24 | Samumed, Llc | 5-substituted indazole-3-carboxamides and preparation and use thereof |
AU2015313811A1 (en) | 2014-09-08 | 2017-04-06 | Yeda Research And Development Co. Ltd. | Compositions and methods for treating cancer resistant to a tyrosine kinase inhibitor (TKI) |
WO2016055916A1 (en) * | 2014-10-06 | 2016-04-14 | Novartis Ag | Therapeutic combination for the treatment of cancer |
AU2015402778B2 (en) | 2015-07-23 | 2020-10-29 | Calgent Biotechnology Co., Ltd. | Aminonapthoquinone compounds and pharmaceutical composition for blocking ubiquitination-proteasome system in diseases |
KR102494174B1 (ko) | 2016-04-15 | 2023-02-02 | 펠리시텍스 쎄라퓨틱스, 인코포레이티드 | 정지 세포 표적화 및 egfr 억제제를 이용하는 신생물 치료를 위한 조합 |
US10314843B2 (en) | 2016-04-15 | 2019-06-11 | Felicitex Therapeutics, Inc. | Combinations for the treatment of neoplasms using quiescent cell targeting and inhibitors of mitosis |
-
2017
- 2017-04-14 KR KR1020187033052A patent/KR102494174B1/ko active IP Right Grant
- 2017-04-14 WO PCT/US2017/027719 patent/WO2017181075A1/en active Application Filing
- 2017-04-14 BR BR112018071031-8A patent/BR112018071031A2/pt not_active Application Discontinuation
- 2017-04-14 KR KR1020237002826A patent/KR20230020565A/ko not_active Application Discontinuation
- 2017-04-14 CA CA3021021A patent/CA3021021A1/en active Pending
- 2017-04-14 MX MX2018012511A patent/MX2018012511A/es unknown
- 2017-04-14 EP EP17783286.2A patent/EP3442505A4/en active Pending
- 2017-04-14 JP JP2018554361A patent/JP7123806B2/ja active Active
- 2017-04-14 US US15/488,116 patent/US10322128B2/en active Active
- 2017-04-14 CN CN201780037696.7A patent/CN109562176A/zh active Pending
- 2017-04-14 AU AU2017248762A patent/AU2017248762A1/en not_active Abandoned
-
2018
- 2018-10-11 IL IL262323A patent/IL262323B/en unknown
- 2018-10-12 MX MX2023000549A patent/MX2023000549A/es unknown
-
2019
- 2019-06-17 US US16/442,973 patent/US11202779B2/en active Active
-
2021
- 2021-12-08 IL IL288777A patent/IL288777A/en unknown
- 2021-12-20 US US17/556,869 patent/US20220110940A1/en active Pending
-
2022
- 2022-08-08 JP JP2022126194A patent/JP2022145800A/ja active Pending
-
2023
- 2023-01-27 AU AU2023200428A patent/AU2023200428A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA3021021A1 (en) | 2017-10-19 |
AU2017248762A1 (en) | 2018-11-01 |
US20220110940A1 (en) | 2022-04-14 |
US10322128B2 (en) | 2019-06-18 |
US20170296541A1 (en) | 2017-10-19 |
IL262323A (en) | 2018-11-29 |
IL262323B (en) | 2022-03-01 |
KR102494174B1 (ko) | 2023-02-02 |
MX2023000549A (es) | 2023-02-13 |
JP2019511554A (ja) | 2019-04-25 |
KR20230020565A (ko) | 2023-02-10 |
BR112018071031A2 (pt) | 2019-02-12 |
EP3442505A4 (en) | 2019-12-18 |
US11202779B2 (en) | 2021-12-21 |
JP2022145800A (ja) | 2022-10-04 |
AU2023200428A1 (en) | 2023-03-02 |
EP3442505A1 (en) | 2019-02-20 |
US20190298723A1 (en) | 2019-10-03 |
KR20180132882A (ko) | 2018-12-12 |
JP7123806B2 (ja) | 2022-08-23 |
CN109562176A (zh) | 2019-04-02 |
WO2017181075A1 (en) | 2017-10-19 |
IL288777A (en) | 2022-02-01 |
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