CA3003294A1 - Modified epha4 and uses thereof - Google Patents
Modified epha4 and uses thereof Download PDFInfo
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- CA3003294A1 CA3003294A1 CA3003294A CA3003294A CA3003294A1 CA 3003294 A1 CA3003294 A1 CA 3003294A1 CA 3003294 A CA3003294 A CA 3003294A CA 3003294 A CA3003294 A CA 3003294A CA 3003294 A1 CA3003294 A1 CA 3003294A1
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- epha4
- amino acid
- modified
- disease
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Classifications
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- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70535—Fc-receptors, e.g. CD16, CD32, CD64 (CD2314/705F)
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
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- Molecular Biology (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2015904387A AU2015904387A0 (en) | 2015-10-27 | A method of treatment and agents useful for same | |
| AU2015904387 | 2015-10-27 | ||
| PCT/AU2016/051010 WO2017070738A1 (en) | 2015-10-27 | 2016-10-27 | A method of treatment and agents useful for same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3003294A1 true CA3003294A1 (en) | 2017-05-04 |
Family
ID=58629613
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3003294A Pending CA3003294A1 (en) | 2015-10-27 | 2016-10-27 | Modified epha4 and uses thereof |
Country Status (8)
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| CN110702916B (zh) * | 2019-04-15 | 2022-06-21 | 四川大学华西医院 | 一种整合蛋白质组和糖蛋白组的定量分析方法 |
| AU2022239581A1 (en) * | 2021-03-18 | 2023-10-26 | Valery Krasnoperov | Use of sephb4-hsa fusion protein as a first-line therapy in cancer treatment |
| US20240385190A1 (en) * | 2021-11-11 | 2024-11-21 | Eisai R&D Management Co., Ltd. | Anti-epha4 antibody |
| WO2023154948A1 (en) * | 2022-02-14 | 2023-08-17 | Vasgene Therapeutics Inc. | Ephrin type-b receptor 4 (ephb4) agents and production thereof |
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| EP0425731B1 (de) | 1989-11-03 | 1994-01-19 | Siemens Aktiengesellschaft | Controller-Bussystem für einen programmierbaren, flexiblen Digitalsignal-Multiplexer |
| GB9022788D0 (en) | 1990-10-19 | 1990-12-05 | Cortecs Ltd | Pharmaceutical formulations |
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| AU688776B2 (en) | 1993-06-23 | 1998-03-19 | Brown University Research Foundation | Method and apparatus for sealing implantable, membrane encapsulation devices |
| EP1179350A3 (en) | 1993-08-12 | 2003-01-02 | Cytotherapeutics, Inc. | Encapsulated cell system for implantation into the human CNS |
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| US5776747A (en) | 1994-07-20 | 1998-07-07 | Cytotherapeutics, Inc. | Method for controlling the distribution of cells within a bioartificial organ using polycthylene oxide-poly (dimethylsiloxane) copolymer |
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| AUPP674898A0 (en) * | 1998-10-27 | 1998-11-19 | Walter And Eliza Hall Institute Of Medical Research, The | A method of treatment |
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| US20080003210A1 (en) * | 2006-03-13 | 2008-01-03 | Medimmune, Inc. | Non-human primate receptor tyrosine kinases |
| EP2166110B1 (en) * | 2007-06-08 | 2012-02-22 | Eisai R&D Management Co., Ltd. | Screening method utilizing novel substrate epha4 for gamma-secretase |
| DK2223999T3 (en) * | 2007-11-30 | 2017-12-18 | Eisai R&D Man Co Ltd | EPHA4 POLYPEPTIDE WITH UNKNOWN ACTIVITY AND USE THEREOF |
| EP2260864A1 (en) * | 2009-06-10 | 2010-12-15 | University of Melbourne | Therapeutic applications |
| EP2653552B1 (en) * | 2010-12-17 | 2016-10-19 | Eisai R&D Management Co., Ltd. | SCREENING METHOD USING GELATINASE-MEDIATED EphA4 CLEAVAGE REACTION AS AN INDICATOR |
| AU2014218318B2 (en) | 2013-02-18 | 2018-02-15 | Vegenics Pty Limited | Ligand binding molecules and uses thereof |
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| US20180339020A1 (en) | 2018-11-29 |
| CN108884135A (zh) | 2018-11-23 |
| JP6877419B2 (ja) | 2021-05-26 |
| CN108884135B (zh) | 2024-03-26 |
| EP3368551A4 (en) | 2019-06-05 |
| AU2016345063A1 (en) | 2018-05-17 |
| JP2019501112A (ja) | 2019-01-17 |
| AU2016345063A2 (en) | 2018-07-19 |
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