CA3001260A1 - Methods of treatment using anti-il-17a/f antibodies - Google Patents

Methods of treatment using anti-il-17a/f antibodies Download PDF

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Publication number
CA3001260A1
CA3001260A1 CA3001260A CA3001260A CA3001260A1 CA 3001260 A1 CA3001260 A1 CA 3001260A1 CA 3001260 A CA3001260 A CA 3001260A CA 3001260 A CA3001260 A CA 3001260A CA 3001260 A1 CA3001260 A1 CA 3001260A1
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CA
Canada
Prior art keywords
human
antibody
seq
week
weeks
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3001260A
Other languages
English (en)
French (fr)
Inventor
Sophie GLATT
Lucian IONESCU
Margaret Jones
Ruth Oliver
Stevan Graham Shaw
Foteini STRIMENOPOULOU
Venkata Pavan Kumar VAJJAH
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UCB Biopharma SRL
Original Assignee
UCB Biopharma SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=57223670&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA3001260(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by UCB Biopharma SRL filed Critical UCB Biopharma SRL
Publication of CA3001260A1 publication Critical patent/CA3001260A1/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA3001260A 2015-10-27 2016-10-26 Methods of treatment using anti-il-17a/f antibodies Pending CA3001260A1 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201562246989P 2015-10-27 2015-10-27
US62/246,989 2015-10-27
US201662303230P 2016-03-03 2016-03-03
US62/303,230 2016-03-03
US201662346826P 2016-06-07 2016-06-07
US62/346,826 2016-06-07
US201662405546P 2016-10-07 2016-10-07
US62/405,546 2016-10-07
PCT/EP2016/075821 WO2017072183A1 (en) 2015-10-27 2016-10-26 Methods of treatment using anti-il-17a/f antibodies

Publications (1)

Publication Number Publication Date
CA3001260A1 true CA3001260A1 (en) 2017-05-04

Family

ID=57223670

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3001260A Pending CA3001260A1 (en) 2015-10-27 2016-10-26 Methods of treatment using anti-il-17a/f antibodies

Country Status (16)

Country Link
US (3) US11492396B2 (https=)
EP (1) EP3368570A1 (https=)
JP (5) JP6931648B2 (https=)
KR (2) KR20240156437A (https=)
CN (2) CN116059350A (https=)
AU (2) AU2016347471B2 (https=)
BR (1) BR112018008075A2 (https=)
CA (1) CA3001260A1 (https=)
CL (3) CL2018001135A1 (https=)
CO (1) CO2018004493A2 (https=)
IL (2) IL258515B1 (https=)
MX (4) MX2018005031A (https=)
MY (3) MY206805A (https=)
RU (1) RU2754683C2 (https=)
SG (2) SG11201802887PA (https=)
WO (1) WO2017072183A1 (https=)

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WO2018119142A1 (en) 2016-12-21 2018-06-28 Amgen Inc. Anti-tnf alpha antibody formulations
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GB201719447D0 (en) * 2017-11-23 2018-01-10 Ucb Biopharma Sprl Pharmaceutical composition
WO2021050563A1 (en) * 2019-09-09 2021-03-18 The Rockefeller University Antibody treatment for lesional tissue of hidradenitis suppurativa
US20230167497A1 (en) * 2020-04-30 2023-06-01 Xiaohua Xue Methods of identifying modulators of the il-17 pathway
WO2022127842A1 (zh) * 2020-12-17 2022-06-23 上海华奥泰生物药业股份有限公司 靶向il-17a和il-36r的双特异性抗体及其应用
EP4471427A1 (en) * 2023-05-31 2024-12-04 Centre Hospitalier Universitaire De Nice Biomarker for spondyloarthitis diagnostic and response to treatment
CN117866905B (zh) * 2024-03-12 2024-06-04 北京贝来药业有限公司 基于纳米抗体基因修饰的干细胞及其制备方法和产品
US20260070969A1 (en) * 2024-09-11 2026-03-12 Paragon Therapeutics, Inc. Il-17 binding proteins, compositions, and methods of use thereof

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Also Published As

Publication number Publication date
JP2018535961A (ja) 2018-12-06
JP2021130707A (ja) 2021-09-09
MX2022009380A (es) 2022-09-07
US20230287100A1 (en) 2023-09-14
CN116059350A (zh) 2023-05-05
MY196489A (en) 2023-04-17
US20190292255A1 (en) 2019-09-26
CL2021002815A1 (es) 2022-07-29
BR112018008075A2 (en) 2018-12-04
JP6931750B2 (ja) 2021-09-08
JP7176044B2 (ja) 2022-11-21
US11492396B2 (en) 2022-11-08
MX2022009379A (es) 2022-09-07
MX2023004315A (es) 2023-05-08
MY207225A (en) 2025-02-06
CL2021002816A1 (es) 2022-07-29
WO2017072183A1 (en) 2017-05-04
RU2018118029A (ru) 2019-12-04
JP2023025019A (ja) 2023-02-21
AU2016347471B2 (en) 2023-08-03
MY206805A (en) 2025-01-08
AU2023255037A1 (en) 2023-11-16
JP6931648B2 (ja) 2021-09-08
IL258515A (en) 2018-05-31
IL325567A (en) 2026-02-01
AU2016347471A1 (en) 2018-05-10
SG10202112586WA (en) 2021-12-30
CN108350068A (zh) 2018-07-31
CL2018001135A1 (es) 2019-05-10
CO2018004493A2 (es) 2018-11-30
MX2018005031A (es) 2018-06-13
IL258515B1 (en) 2026-01-01
SG11201802887PA (en) 2018-05-30
RU2754683C2 (ru) 2021-09-06
RU2018118029A3 (https=) 2020-09-17
JP2025037926A (ja) 2025-03-18
US20230279093A1 (en) 2023-09-07
JP2021119168A (ja) 2021-08-12
EP3368570A1 (en) 2018-09-05
KR20240156437A (ko) 2024-10-29
KR20180067676A (ko) 2018-06-20

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