CA2986133A1 - Methods of discriminating between hiv-1 and lentiviral vectors - Google Patents

Methods of discriminating between hiv-1 and lentiviral vectors Download PDF

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Publication number
CA2986133A1
CA2986133A1 CA2986133A CA2986133A CA2986133A1 CA 2986133 A1 CA2986133 A1 CA 2986133A1 CA 2986133 A CA2986133 A CA 2986133A CA 2986133 A CA2986133 A CA 2986133A CA 2986133 A1 CA2986133 A1 CA 2986133A1
Authority
CA
Canada
Prior art keywords
nucleic acid
hiv
sequence
seq
probe
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2986133A
Other languages
English (en)
French (fr)
Inventor
Kazuo Suzuki
Anthony Dominic Kelleher
Geoffrey Phillip Symonds
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NewSouth Innovations Pty Ltd
St Vincents Hospital Sydney Ltd
CSL Gene Therapy Pty Ltd
CSL Behring Gene Therapy Inc
Original Assignee
NewSouth Innovations Pty Ltd
St Vincents Hospital Sydney Ltd
Calimmune Australia Pty Ltd
Calimmune Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NewSouth Innovations Pty Ltd, St Vincents Hospital Sydney Ltd, Calimmune Australia Pty Ltd, Calimmune Inc filed Critical NewSouth Innovations Pty Ltd
Publication of CA2986133A1 publication Critical patent/CA2986133A1/en
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/702—Specific hybridization probes for retroviruses
    • C12Q1/703—Viruses associated with AIDS
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16041—Use of virus, viral particle or viral elements as a vector
    • C12N2740/16043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • AIDS & HIV (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CA2986133A 2015-05-18 2016-05-16 Methods of discriminating between hiv-1 and lentiviral vectors Abandoned CA2986133A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562163327P 2015-05-18 2015-05-18
US62/163,327 2015-05-18
PCT/US2016/032767 WO2016187151A1 (en) 2015-05-18 2016-05-16 Methods of discriminating between hiv-1 and lentiviral vectors

Publications (1)

Publication Number Publication Date
CA2986133A1 true CA2986133A1 (en) 2016-11-24

Family

ID=56121165

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2986133A Abandoned CA2986133A1 (en) 2015-05-18 2016-05-16 Methods of discriminating between hiv-1 and lentiviral vectors

Country Status (10)

Country Link
US (2) US10240214B2 (enExample)
EP (1) EP3283658B1 (enExample)
JP (1) JP2018516594A (enExample)
CN (1) CN108026593A (enExample)
AU (1) AU2016265839A1 (enExample)
CA (1) CA2986133A1 (enExample)
DK (1) DK3283658T3 (enExample)
ES (1) ES2784351T3 (enExample)
HK (1) HK1247965A1 (enExample)
WO (1) WO2016187151A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3414340B1 (en) * 2016-02-12 2023-08-09 CureVac SE Method for analyzing rna
US11920174B2 (en) 2016-03-03 2024-03-05 CureVac SE RNA analysis by total hydrolysis and quantification of released nucleosides
US20210332448A1 (en) * 2020-03-09 2021-10-28 Janssen Pharmaceutica Nv Compositions and methods for quantifying integration of recombinant vector nucleic acid
CN111961760A (zh) * 2020-09-02 2020-11-20 苏州市第五人民医院 基于ddPCR自动化检测HIV-1的引物组、探针组、试剂盒及用途
CN114134251B (zh) * 2020-09-04 2025-04-01 上海赛比曼生物科技有限公司 一种快速检测慢病毒载体滴度的方法
CN112210625A (zh) * 2020-11-02 2021-01-12 中山大学达安基因股份有限公司 定量检测人类免疫缺陷病毒1型dna载量的试剂盒及方法
CN113151587A (zh) * 2021-01-28 2021-07-23 云舟生物科技（广州）有限公司 一种慢病毒滴度检测引物、试剂盒及检测方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4000159A (en) 1974-06-28 1976-12-28 Phillips Petroleum Company Preparation of n,n-disubstituted thioamides
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4965188A (en) 1986-08-22 1990-10-23 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
US5176995A (en) 1985-03-28 1993-01-05 Hoffmann-La Roche Inc. Detection of viruses by amplification and hybridization
ATE282716T1 (de) * 1989-07-11 2004-12-15 Gen Probe Inc Verfahren zur amplifikation von nukleinsäuresequenzen
WO1992020813A1 (en) * 1991-05-17 1992-11-26 Dana Farber Cancer Institute Assays for factors affecting circularization of dna, assays for factors affecting dna integration, factors, and uses thereof
US5578444A (en) * 1991-06-27 1996-11-26 Genelabs Technologies, Inc. Sequence-directed DNA-binding molecules compositions and methods
US5576176A (en) * 1994-03-03 1996-11-19 The Regents Of The University Of California Marker and an assay for detection and monitoring of human immunodeficiency virus latency and activation
US20030104576A1 (en) * 1994-10-07 2003-06-05 Jonathan W. Nyce Dna construct, composition, formulations & methods for making the construct & for modulating expression
DE19907485B4 (de) * 1999-02-12 2008-01-17 Strathmann Ag & Co. Virus-Vakzine
US8889844B2 (en) * 2005-08-16 2014-11-18 Takara Bio Inc. Nucleic acid for treatment or prevention of immunodeficiency virus infection
DK3329772T3 (da) 2009-07-15 2020-01-27 Calimmune Inc Dobbeltvektor til inhibering af human immundefektvirus
WO2011011584A1 (en) 2009-07-24 2011-01-27 Immune Design Corp Lentiviral vectors pseudotyped with a sindbis virus envelope glycoprotein
WO2012141984A1 (en) * 2011-04-08 2012-10-18 Immune Design Corp. Immunogenic compositions and methods of using the compositions for inducing humoral and cellular immune responses
CA2882020A1 (en) * 2012-08-16 2014-02-20 NVS Technologies, Inc. Assay methods and systems
CN103882062A (zh) * 2014-03-13 2014-06-25 山西大学 慢病毒干扰载体pll3.7-Neo及其构建方法

Also Published As

Publication number Publication date
EP3283658A1 (en) 2018-02-21
EP3283658B1 (en) 2020-03-11
US11008630B2 (en) 2021-05-18
HK1247965A1 (zh) 2018-10-05
US10240214B2 (en) 2019-03-26
CN108026593A (zh) 2018-05-11
WO2016187151A1 (en) 2016-11-24
ES2784351T3 (es) 2020-09-24
DK3283658T3 (da) 2020-05-18
US20190153551A1 (en) 2019-05-23
AU2016265839A1 (en) 2017-12-07
JP2018516594A (ja) 2018-06-28
US20180066325A1 (en) 2018-03-08

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20171115

EEER Examination request

Effective date: 20171115

FZDE Discontinued

Effective date: 20230419

FZDE Discontinued

Effective date: 20230419