CA2983224A1 - Multiplexed method for the identification and quantitation of minor alleles and polymorphisms - Google Patents

Multiplexed method for the identification and quantitation of minor alleles and polymorphisms Download PDF

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Publication number
CA2983224A1
CA2983224A1 CA2983224A CA2983224A CA2983224A1 CA 2983224 A1 CA2983224 A1 CA 2983224A1 CA 2983224 A CA2983224 A CA 2983224A CA 2983224 A CA2983224 A CA 2983224A CA 2983224 A1 CA2983224 A1 CA 2983224A1
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CA
Canada
Prior art keywords
nucleic acid
acid species
minor
major
chain terminating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2983224A
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English (en)
French (fr)
Inventor
Anders Olof Herman Nygren
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Agena Bioscience Inc
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Agena Bioscience Inc
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Filing date
Publication date
Application filed by Agena Bioscience Inc filed Critical Agena Bioscience Inc
Publication of CA2983224A1 publication Critical patent/CA2983224A1/en
Abandoned legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA2983224A 2015-04-24 2016-04-22 Multiplexed method for the identification and quantitation of minor alleles and polymorphisms Abandoned CA2983224A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562152697P 2015-04-24 2015-04-24
US62/152,697 2015-04-24
US201662280951P 2016-01-20 2016-01-20
US62/280,951 2016-01-20
PCT/US2016/028971 WO2016172571A1 (en) 2015-04-24 2016-04-22 Multiplexed method for the identification and quantitation of minor alleles and polymorphisms

Publications (1)

Publication Number Publication Date
CA2983224A1 true CA2983224A1 (en) 2016-10-27

Family

ID=55911096

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2983224A Abandoned CA2983224A1 (en) 2015-04-24 2016-04-22 Multiplexed method for the identification and quantitation of minor alleles and polymorphisms

Country Status (8)

Country Link
US (5) US10233489B2 (OSRAM)
EP (2) EP4001430A1 (OSRAM)
JP (5) JP2018512880A (OSRAM)
CN (2) CN107406882B (OSRAM)
AU (1) AU2016250841A1 (OSRAM)
CA (1) CA2983224A1 (OSRAM)
HK (1) HK1250747A1 (OSRAM)
WO (1) WO2016172571A1 (OSRAM)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2835942C (en) 2011-05-19 2019-01-22 Sequenom, Inc. Products and processes for multiplex nucleic acid identification
CA2983224A1 (en) 2015-04-24 2016-10-27 Agena Bioscience, Inc. Multiplexed method for the identification and quantitation of minor alleles and polymorphisms
CN114350766A (zh) 2015-04-24 2022-04-15 基纳生物技术有限公司 检测和定量次要变体的并行式方法
WO2019232460A1 (en) 2018-06-01 2019-12-05 Agena Bioscience, Inc. Products and processes for nucleic acid detection and quantification
CN113466320B (zh) * 2021-08-06 2022-10-14 河北省食品检验研究院 一种针对乳粉中牛源性成分maldi-tof检测方法
KR102857507B1 (ko) 2022-11-14 2025-09-10 명지대학교 산학협력단 무의 근피 색상 판별용 snp 마커 및 이의 용도

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CN114350766A (zh) 2015-04-24 2022-04-15 基纳生物技术有限公司 检测和定量次要变体的并行式方法

Also Published As

Publication number Publication date
US20190153526A1 (en) 2019-05-23
EP4001430A1 (en) 2022-05-25
US12454722B2 (en) 2025-10-28
JP2021097718A (ja) 2021-07-01
JP2024012522A (ja) 2024-01-30
US20210062254A1 (en) 2021-03-04
JP7325467B2 (ja) 2023-08-14
US20200123601A1 (en) 2020-04-23
CN107406882A (zh) 2017-11-28
AU2016250841A1 (en) 2017-11-02
JP2021097719A (ja) 2021-07-01
CN107406882B (zh) 2022-03-01
HK1250747A1 (zh) 2019-01-11
EP3286327B1 (en) 2021-11-10
EP3286327A1 (en) 2018-02-28
JP2019083820A (ja) 2019-06-06
US20230383340A1 (en) 2023-11-30
US20160312278A1 (en) 2016-10-27
US10865439B2 (en) 2020-12-15
US10233489B2 (en) 2019-03-19
JP2018512880A (ja) 2018-05-24
US11680289B2 (en) 2023-06-20
WO2016172571A1 (en) 2016-10-27
US10513728B2 (en) 2019-12-24
CN114540470A (zh) 2022-05-27

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Legal Events

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Effective date: 20220301