CA2982536C - Antibodies, compositions, and immunohistochemistry methods for detecting c4.4a - Google Patents
Antibodies, compositions, and immunohistochemistry methods for detecting c4.4a Download PDFInfo
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Classifications
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- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/567—Framework region [FR]
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
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- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
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| US201562149239P | 2015-04-17 | 2015-04-17 | |
| US62/149,239 | 2015-04-17 | ||
| PCT/EP2016/058135 WO2016166169A1 (en) | 2015-04-17 | 2016-04-13 | Antibodies, compositions, and immunohistochemistry methods for detecting c4.4a |
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| WO2016166169A1 (en) * | 2015-04-17 | 2016-10-20 | Spring Bioscience Corporation | Antibodies, compositions, and immunohistochemistry methods for detecting c4.4a |
| CN111349164B (zh) * | 2018-12-21 | 2023-05-26 | 艾比玛特医药科技（上海）有限公司 | 糖基磷脂酰肌醇锚定糖蛋白（c4.4a）的单克隆抗体及其应用 |
| WO2022261403A1 (en) * | 2021-06-11 | 2022-12-15 | Memorial Sloan-Kettering Cancer Center | Antigen recognizing receptors targeting upar and uses thereof |
| AU2023234686A1 (en) * | 2022-03-16 | 2024-08-29 | Pentixapharm Ag | Antibodies against lypd3 |
| CA3258344A1 (en) | 2022-06-07 | 2023-12-14 | Actinium Pharmaceuticals Inc | CHELETARIANS AND BIFUNCTIONAL CONJUGATES |
| CN116086919B (zh) * | 2023-02-20 | 2024-01-26 | 深圳裕策生物科技有限公司 | 一种肺癌和/或胰腺癌样本的染色方法及试剂盒 |
| WO2025149667A1 (en) | 2024-01-12 | 2025-07-17 | Pheon Therapeutics Ltd | Antibody drug conjugates and uses thereof |
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| US6649138B2 (en) | 2000-10-13 | 2003-11-18 | Quantum Dot Corporation | Surface-modified semiconductive and metallic nanoparticles having enhanced dispersibility in aqueous media |
| US20020083888A1 (en) | 2000-12-28 | 2002-07-04 | Zehnder Donald A. | Flow synthesis of quantum dot nanocrystals |
| US6670113B2 (en) | 2001-03-30 | 2003-12-30 | Nanoprobes | Enzymatic deposition and alteration of metals |
| ATE556845T1 (de) | 2001-07-20 | 2012-05-15 | Life Technologies Corp | Lumineszierende nanopartikel und ihre herstellung |
| US8420353B2 (en) | 2002-03-22 | 2013-04-16 | Aprogen, Inc. | Humanized antibody and process for preparing same |
| US7632652B2 (en) | 2003-06-24 | 2009-12-15 | Ventana Medical Systems, Inc. | Enzyme-catalyzed metal deposition for the enhanced in situ detection of immunohistochemical epitopes and nucleic acid sequences |
| US7642064B2 (en) | 2003-06-24 | 2010-01-05 | Ventana Medical Systems, Inc. | Enzyme-catalyzed metal deposition for the enhanced detection of analytes of interest |
| DK2078197T3 (en) | 2006-11-01 | 2016-05-23 | Ventana Med Syst Inc | Haptenes, hapten conjugates, compositions thereof and processes for their preparation and use |
| MX343879B (es) * | 2007-05-21 | 2016-11-25 | Alderbio Holdings Llc | Metodo de humanizacion de anticuerpo de conejo novedoso y anticuerpos de conejo humanizados. |
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| JP5989544B2 (ja) * | 2009-12-09 | 2016-09-07 | バイエル・ファルマ・アクティエンゲゼルシャフト | 抗Ｃ４．４ａ抗体およびその使用 |
| JP5881604B2 (ja) | 2010-06-15 | 2016-03-09 | 国立大学法人大阪大学 | 癌予後判定可能な抗体、および癌予後判定方法 |
| TWI582112B (zh) * | 2011-04-21 | 2017-05-11 | 西雅圖遺傳學公司 | 新穎結合劑－藥物接合物（ＡＤＣｓ）及其用途（二） |
| CN103688176A (zh) * | 2011-04-29 | 2014-03-26 | 细胞基因公司 | 利用cereblon作为预报因子治疗癌和炎性疾病的方法 |
| WO2012158780A2 (en) | 2011-05-16 | 2012-11-22 | The Regents Of The University Of Michigan | Lung cancer signature |
| KR20150013935A (ko) | 2012-06-08 | 2015-02-05 | 갓코 호진 긴키 다이가쿠 | 트랜스포터에 대한 항체 및 이의 용도 |
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| US20160115237A1 (en) * | 2013-05-24 | 2016-04-28 | The University Of British Columbia | Cell senescence markers as diagnostic and therapeutic targets |
| AU2015315332A1 (en) * | 2014-09-09 | 2017-03-30 | Board Of Regents, The University Of Texas System | Blocking monoclonal antibodies to AGR2 and its receptor C4.4A |
| WO2016166169A1 (en) * | 2015-04-17 | 2016-10-20 | Spring Bioscience Corporation | Antibodies, compositions, and immunohistochemistry methods for detecting c4.4a |
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Also Published As
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| WO2016166169A1 (en) | 2016-10-20 |
| JP6720208B2 (ja) | 2020-07-08 |
| US11719699B2 (en) | 2023-08-08 |
| US20180031566A1 (en) | 2018-02-01 |
| EP3283522A1 (en) | 2018-02-21 |
| CA2982536A1 (en) | 2016-10-20 |
| US20210164985A1 (en) | 2021-06-03 |
| US10948493B2 (en) | 2021-03-16 |
| AU2016249839A1 (en) | 2017-09-21 |
| JP2018515071A (ja) | 2018-06-14 |
| AU2016249839B2 (en) | 2021-09-09 |
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