CA2982251C - Combinations of amisulpride and another anti-emetic for treating nausea and vomiting - Google Patents
Combinations of amisulpride and another anti-emetic for treating nausea and vomiting Download PDFInfo
- Publication number
- CA2982251C CA2982251C CA2982251A CA2982251A CA2982251C CA 2982251 C CA2982251 C CA 2982251C CA 2982251 A CA2982251 A CA 2982251A CA 2982251 A CA2982251 A CA 2982251A CA 2982251 C CA2982251 C CA 2982251C
- Authority
- CA
- Canada
- Prior art keywords
- amisulpride
- emetic
- injectable
- kit
- phase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
- NTJOBXMMWNYJFB-UHFFFAOYSA-N amisulpride Chemical compound CCN1CCCC1CNC(=O)C1=CC(S(=O)(=O)CC)=C(N)C=C1OC NTJOBXMMWNYJFB-UHFFFAOYSA-N 0.000 title claims abstract description 317
- 229960003036 amisulpride Drugs 0.000 title claims abstract description 317
- 239000002111 antiemetic agent Substances 0.000 title claims abstract description 74
- 230000003474 anti-emetic effect Effects 0.000 title claims abstract description 63
- 206010047700 Vomiting Diseases 0.000 title claims abstract description 48
- 238000001959 radiotherapy Methods 0.000 claims abstract description 56
- 238000002512 chemotherapy Methods 0.000 claims abstract description 49
- 206010028813 Nausea Diseases 0.000 claims abstract description 39
- 230000008693 nausea Effects 0.000 claims abstract description 39
- 230000008673 vomiting Effects 0.000 claims abstract description 35
- 239000007972 injectable composition Substances 0.000 claims abstract description 24
- 238000011282 treatment Methods 0.000 claims abstract description 24
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- 239000000203 mixture Substances 0.000 claims description 59
- 238000001990 intravenous administration Methods 0.000 claims description 51
- NTJOBXMMWNYJFB-LBPRGKRZSA-N 4-amino-n-[[(2s)-1-ethylpyrrolidin-2-yl]methyl]-5-ethylsulfonyl-2-methoxybenzamide Chemical compound CCN1CCC[C@H]1CNC(=O)C1=CC(S(=O)(=O)CC)=C(N)C=C1OC NTJOBXMMWNYJFB-LBPRGKRZSA-N 0.000 claims description 37
- 238000009472 formulation Methods 0.000 claims description 17
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
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| PCT/GB2016/050998 WO2016162695A1 (en) | 2015-04-10 | 2016-04-11 | Combinations of amisulpride and another anti-emetic for treating nausea and vomiting |
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| CN118593482A (zh) | 2017-12-05 | 2024-09-06 | 赛诺维信制药公司 | 非外消旋混合物及其用途 |
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| CN120693338A (zh) | 2022-12-22 | 2025-09-23 | 加舒布鲁姆生物公司 | 杂环的glp-1激动剂 |
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| US20150018360A1 (en) * | 2011-09-13 | 2015-01-15 | Biomed Valley Discoveries, Inc. | Compositions and methods for treating metabolic disorders |
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| PT3280392T (pt) | 2021-03-12 |
| CY1124184T1 (el) | 2022-07-22 |
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| ES2866933T3 (es) | 2021-10-20 |
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