CN107872975A - 用于治疗恶心和呕吐的氨磺必利和其它止吐药的组合 - Google Patents
用于治疗恶心和呕吐的氨磺必利和其它止吐药的组合 Download PDFInfo
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- CN107872975A CN107872975A CN201680030994.9A CN201680030994A CN107872975A CN 107872975 A CN107872975 A CN 107872975A CN 201680030994 A CN201680030994 A CN 201680030994A CN 107872975 A CN107872975 A CN 107872975A
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- amisulpride
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- antiemetic
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- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
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- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
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- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
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Landscapes
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- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
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- General Health & Medical Sciences (AREA)
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- Life Sciences & Earth Sciences (AREA)
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- Otolaryngology (AREA)
- Hospice & Palliative Care (AREA)
- Physiology (AREA)
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- Medicinal Preparation (AREA)
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| PCT/GB2016/050998 WO2016162695A1 (en) | 2015-04-10 | 2016-04-11 | Combinations of amisulpride and another anti-emetic for treating nausea and vomiting |
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| GB201702250D0 (en) * | 2017-02-10 | 2017-03-29 | Acacia Pharma Ltd | Method |
| AU2018379992B2 (en) | 2017-12-05 | 2022-07-21 | Sunovion Pharmaceuticals Inc. | Nonracemic mixtures and uses thereof |
| US10377708B2 (en) | 2017-12-05 | 2019-08-13 | Sunovion Pharmaceuticals Inc. | Crystal forms and production methods thereof |
| US11160758B2 (en) | 2019-06-04 | 2021-11-02 | Sunovion Pharmaceuticals Inc. | Modified release formulations and uses thereof |
| EP4496797A1 (en) | 2022-03-21 | 2025-01-29 | Gasherbrum Bio, Inc. | 5,8-dihydro-1,7-naphthyridine derivatives as glp-1 agonists for the treatment of diabetes |
| JP2025513071A (ja) | 2022-04-14 | 2025-04-22 | ガシャーブラム・バイオ・インコーポレイテッド | ヘテロ環式ｇｌｐ－１アゴニスト |
| EP4634180A1 (en) | 2022-12-15 | 2025-10-22 | Gasherbrum Bio, Inc. | Salts and solid forms of a compound having glp-1 agonist activity |
| EP4638440A1 (en) | 2022-12-22 | 2025-10-29 | Gasherbrum Bio, Inc. | Heterocyclic glp-1 agonists |
| WO2024138048A1 (en) | 2022-12-22 | 2024-06-27 | Gasherbrum Bio, Inc. | Heterocyclic glp-1 agonists |
| IL322686A (en) | 2023-02-16 | 2025-10-01 | Gasherbrum Bio Inc | Heterocyclic glp-1 agonists |
| TW202506102A (zh) | 2023-06-30 | 2025-02-16 | 美商迦舒布魯姆生物有限公司 | 雜環的glp-1促效劑 |
| WO2025015269A1 (en) | 2023-07-13 | 2025-01-16 | Aconcagua Bio, Inc. | Compounds, compositions, and methods |
| AR133240A1 (es) | 2023-07-13 | 2025-09-10 | Aconcagua Bio Inc | Compuestos, composiciones y métodos |
| WO2025045208A1 (en) | 2023-08-31 | 2025-03-06 | Gasherbrum Bio, Inc. | Heteroaryl-heterocycloalkyl-based glp-1 agonists |
| WO2025137307A1 (en) | 2023-12-20 | 2025-06-26 | Gasherbrum Bio, Inc. | Heterocyclic glp-1 agonists |
| WO2025171341A2 (en) | 2024-02-08 | 2025-08-14 | Aconcagua Bio, Inc. | Compounds and compositions for treating conditions associated with calcitonin receptor and/or amylin receptor activity |
| WO2025171340A1 (en) | 2024-02-08 | 2025-08-14 | Aconcagua Bio, Inc. | The treatment of calcitonin- and/or amylin-receptor associated conditions |
| WO2025189141A1 (en) | 2024-03-08 | 2025-09-12 | Annapurna Bio, Inc. | Methods for treating obesity and increasing weight loss |
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| CN102892407A (zh) * | 2010-03-11 | 2013-01-23 | 阿卡西亚制药有限公司 | 氨磺必利作为止吐药的用途 |
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| GB201003962D0 (en) | 2010-03-10 | 2010-04-21 | Tangentix Ltd | Multimedia content delivery system |
| CN103906514A (zh) * | 2011-09-13 | 2014-07-02 | 拜奥迈德瓦利探索有限公司 | 用于治疗代谢障碍的组合物和方法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102892407A (zh) * | 2010-03-11 | 2013-01-23 | 阿卡西亚制药有限公司 | 氨磺必利作为止吐药的用途 |
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| ACACIA PHARMA LTD EU CLINICAL TRIALS REGISTER: "Randomised, double-blind, dose-finding Phase II study to assess the efficacy of APD403 in the prevention of nausea and vomiting caused by cisplatin- or anthracycline cyclophosphamide (AC)-based chemotherapy", 《EU CLINICAL TRIALS REGISTER》 * |
| DR YVONNE SUMMERS: "A trial of APD403 to prevent sickness caused by", 《CANCER RESEARCH UK》 * |
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| JP6812360B2 (ja) | 2021-01-13 |
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| KR20240125705A (ko) | 2024-08-19 |
| IL295650A (en) | 2022-10-01 |
| CA2982251C (en) | 2023-06-13 |
| KR102711661B1 (ko) | 2024-10-02 |
| JP2018510898A (ja) | 2018-04-19 |
| EP3280392B1 (en) | 2021-02-24 |
| KR20180016350A (ko) | 2018-02-14 |
| SMT202100216T1 (it) | 2021-05-07 |
| US20180071249A1 (en) | 2018-03-15 |
| PT3280392T (pt) | 2021-03-12 |
| AU2016246104A1 (en) | 2017-11-30 |
| WO2016162695A1 (en) | 2016-10-13 |
| GB201506116D0 (en) | 2015-05-27 |
| CY1124184T1 (el) | 2022-07-22 |
| CA2982251A1 (en) | 2016-10-13 |
| HRP20210624T1 (hr) | 2021-05-28 |
| LT3280392T (lt) | 2021-04-26 |
| ES2866933T3 (es) | 2021-10-20 |
| DK3280392T3 (da) | 2021-03-08 |
| MX388735B (es) | 2025-03-20 |
| US10322106B2 (en) | 2019-06-18 |
| HK1250913A1 (en) | 2019-01-18 |
| RS61760B1 (sr) | 2021-05-31 |
| HUE054165T2 (hu) | 2021-08-30 |
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