CA2978476C - Preparation of lipemic plasma or serum samples for the determination of a lipid interference - Google Patents

Preparation of lipemic plasma or serum samples for the determination of a lipid interference Download PDF

Info

Publication number
CA2978476C
CA2978476C CA2978476A CA2978476A CA2978476C CA 2978476 C CA2978476 C CA 2978476C CA 2978476 A CA2978476 A CA 2978476A CA 2978476 A CA2978476 A CA 2978476A CA 2978476 C CA2978476 C CA 2978476C
Authority
CA
Canada
Prior art keywords
lipid
plasma
serum sample
analyte
assay
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2978476A
Other languages
English (en)
French (fr)
Other versions
CA2978476A1 (en
Inventor
Juergen Patzke
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics Products GmbH
Original Assignee
Siemens Healthcare Diagnostics Products GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Siemens Healthcare Diagnostics Products GmbH filed Critical Siemens Healthcare Diagnostics Products GmbH
Publication of CA2978476A1 publication Critical patent/CA2978476A1/en
Application granted granted Critical
Publication of CA2978476C publication Critical patent/CA2978476C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/4077—Concentrating samples by other techniques involving separation of suspended solids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/4077—Concentrating samples by other techniques involving separation of suspended solids
    • G01N2001/4083—Concentrating samples by other techniques involving separation of suspended solids sedimentation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/04—Endocrine or metabolic disorders
    • G01N2800/044—Hyperlipemia or hypolipemia, e.g. dyslipidaemia, obesity

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA2978476A 2016-09-08 2017-09-06 Preparation of lipemic plasma or serum samples for the determination of a lipid interference Active CA2978476C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16187839.2 2016-09-08
EP16187839.2A EP3293521B1 (de) 2016-09-08 2016-09-08 Herstellung lipämischer plasma- oder serumproben für die bestimmung einer lipidinterferenz

Publications (2)

Publication Number Publication Date
CA2978476A1 CA2978476A1 (en) 2018-03-08
CA2978476C true CA2978476C (en) 2024-06-18

Family

ID=56936286

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2978476A Active CA2978476C (en) 2016-09-08 2017-09-06 Preparation of lipemic plasma or serum samples for the determination of a lipid interference

Country Status (6)

Country Link
US (1) US10488308B2 (OSRAM)
EP (1) EP3293521B1 (OSRAM)
JP (1) JP7022538B2 (OSRAM)
CN (1) CN107807024B (OSRAM)
CA (1) CA2978476C (OSRAM)
ES (1) ES2720779T3 (OSRAM)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113196064B (zh) * 2019-01-29 2022-09-27 美国西门子医学诊断股份有限公司 降低血红蛋白A1c测定中的英脱利匹特/脂血干扰的浊度归一化算法和方法
CN111929449A (zh) * 2020-08-28 2020-11-13 保定天岳生物工程有限公司 一种aptt检测试剂盒
EP4209234B1 (en) * 2022-01-11 2026-03-25 Fenwal, Inc. Adjustment of target interface position in a centrifuge based on lipid concentration
CN116907961A (zh) * 2023-06-27 2023-10-20 郴州市第一人民医院 一种消减脂血标本血脂干扰的方法
CN119901692B (zh) * 2023-10-28 2025-12-02 柏荣诊断产品(上海)有限公司 一种减弱脂血对透散射融合增强免疫比浊检测影响的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4977685A (OSRAM) * 1972-11-29 1974-07-26
DE4223355A1 (de) * 1992-07-16 1994-01-20 Boehringer Mannheim Gmbh Verfahren und Reagenz zur spezifischen Bestimmung von LDL in Serumproben
JP4273311B2 (ja) 2002-04-26 2009-06-03 株式会社シノテスト 試料中の測定対象物質の測定方法及び測定試薬
CN101398422B (zh) * 2008-10-28 2012-09-05 四川大学华西医院 高甘油三脂对血红蛋白浓度测定干扰的消除方法
US20130084592A1 (en) 2011-10-04 2013-04-04 Siemens Healthcare Diagnostics Inc. Methods for correcting assay measurements

Also Published As

Publication number Publication date
CN107807024A (zh) 2018-03-16
ES2720779T3 (es) 2019-07-24
EP3293521A1 (de) 2018-03-14
CN107807024B (zh) 2021-11-23
US10488308B2 (en) 2019-11-26
CA2978476A1 (en) 2018-03-08
EP3293521B1 (de) 2019-01-02
JP2018040799A (ja) 2018-03-15
US20180067022A1 (en) 2018-03-08
JP7022538B2 (ja) 2022-02-18

Similar Documents

Publication Publication Date Title
US10488308B2 (en) Preparation of lipemic plasma or serum samples for the determination of a lipid interference
Nikolac Lipemia: causes, interference mechanisms, detection and management
Patzke et al. Performance evaluation and multicentre study of a von Willebrand factor activity assay based on GPIb binding in the absence of ristocetin
JP6298043B2 (ja) 自動分析計で流体試料中の被検体の量を測光法により決定するためのマルチアプリケーション法
Bairaktari et al. Estimation of LDL cholesterol based on the Friedewald formula and on apo B levels
Guder et al. The Haemolytic, Icteric and Lipemic Sample-Recommendations Regarding their Recognition and Prevention of Clinically Relevant Interferences
Islam et al. Methods of low-density lipoprotein-cholesterol measurement: analytical and clinical applications
Lee et al. A quick and large-scale density gradient subfractionation method for low density lipoproteins.
KR102072251B1 (ko) 혈액 샘플 분석 방법
NO162094B (no) Fremgangsm te for bestemmelse av lavdensitetslipoprldl) og reagens for gjennomfoering av den.
Yano et al. Comparison of two homogeneous LDL-cholesterol assays using fresh hypertriglyceridemic serum and quantitative ultracentrifugation fractions
US11156618B1 (en) Rapid measurement of total vitamin D in blood
Jialal et al. Comparison of an immunoprecipitation method for direct measurement of LDL-cholesterol with beta-quantification (ultracentrifugation)
WO2003083490A2 (en) Method for predicting antiphospholid syndrome
WO1996004556A1 (en) Lipoprotein cholesterol assays
Belcher et al. A micro-enzymatic method to measure cholesterol and triglyceride in lipoprotein subfractions separated by density gradient ultracentrifugation from 200 microliters of plasma or serum.
CN113884449B (zh) 光度干扰确定
JP2011505866A (ja) 脂質測定方法
US20130224777A1 (en) Screening method for finding samples having antiphospholipid antibodies
Luddington et al. Lupus anticoagulant testing with optical end point automation
WO2025111449A1 (en) Method and reagent to clear turbidity due to elevated triglycerides in a biological specimen
Warnick et al. Multilaboratory evaluation of an ultrafiltration procedure for high density lipoprotein cholesterol quantification in turbid heparin-manganese supernates.
JPS60501425A (ja) 生物に由来する水溶液中のコロイド粒子の特異的除去の後に分析質を直接検出する方法及び試薬
Lopez et al. Automated simultaneous turbidimetric determination of cholesterol in β-and pre-β-lipoproteins
Mainard et al. Are ‘precipitated LDL’really low density lipoproteins?

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20220901

MPN Maintenance fee for patent paid

Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 8TH ANNIV.) - STANDARD

Year of fee payment: 8

U00 Fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED

Effective date: 20250827

U11 Full renewal or maintenance fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL

Effective date: 20250827