CA2972960C - Identification of functional cell states - Google Patents

Identification of functional cell states Download PDF

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Publication number
CA2972960C
CA2972960C CA2972960A CA2972960A CA2972960C CA 2972960 C CA2972960 C CA 2972960C CA 2972960 A CA2972960 A CA 2972960A CA 2972960 A CA2972960 A CA 2972960A CA 2972960 C CA2972960 C CA 2972960C
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cells
cell
tensor
response
agent
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French (fr)
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CA2972960A1 (en
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Bartlomiej Rajwa
T. Vincent Shankey
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ASEDASCIENCES AG
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ASEDASCIENCES AG
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5041—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects involving analysis of members of signalling pathways
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B99/00—Subject matter not provided for in other groups of this subclass
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5026—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on cell morphology
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/30—Prediction of properties of chemical compounds, compositions or mixtures
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/40—Searching chemical structures or physicochemical data
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C99/00—Subject matter not provided for in other groups of this subclass

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Theoretical Computer Science (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Computing Systems (AREA)
  • Physiology (AREA)
  • Evolutionary Biology (AREA)
  • Medical Informatics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
CA2972960A 2014-01-14 2015-01-14 Identification of functional cell states Active CA2972960C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461927247P 2014-01-14 2014-01-14
US61/927,247 2014-01-14
PCT/US2015/011441 WO2015109003A1 (en) 2014-01-14 2015-01-14 Identification of functional cell states

Publications (2)

Publication Number Publication Date
CA2972960A1 CA2972960A1 (en) 2015-07-23
CA2972960C true CA2972960C (en) 2022-01-11

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Family Applications (1)

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CA2972960A Active CA2972960C (en) 2014-01-14 2015-01-14 Identification of functional cell states

Country Status (11)

Country Link
US (3) US20150198584A1 (https=)
EP (1) EP3094974B1 (https=)
JP (1) JP6606100B2 (https=)
KR (1) KR102413041B1 (https=)
AU (2) AU2015206520B2 (https=)
CA (1) CA2972960C (https=)
DK (1) DK3094974T3 (https=)
ES (1) ES2728119T3 (https=)
IL (1) IL246734B (https=)
SG (1) SG11201705495XA (https=)
WO (1) WO2015109003A1 (https=)

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KR102413041B1 (ko) * 2014-01-14 2022-06-23 아세다사이언시즈 아게 기능성 세포 상태의 확인
US10761011B2 (en) 2015-02-24 2020-09-01 The University Of Tokyo Dynamic high-speed high-sensitivity imaging device and imaging method
JP6959614B2 (ja) * 2015-10-28 2021-11-02 国立大学法人 東京大学 分析装置，及びフローサイトメータ
US10824693B2 (en) 2015-12-10 2020-11-03 Reservoir Labs, Inc. Systems and methods for selective expansive recursive tensor analysis
US11205103B2 (en) 2016-12-09 2021-12-21 The Research Foundation for the State University Semisupervised autoencoder for sentiment analysis
US12300357B2 (en) 2016-12-14 2025-05-13 FlowJo, LLC Applied computer technology for management, synthesis, visualization, and exploration of parameters in large multi-parameter data sets
ES2980676T3 (es) 2017-05-25 2024-10-02 Flowjo Llc Visualización, análisis comparativo y detección de diferencias automatizada para grandes conjuntos de datos multiparamétricos
GB2592113B (en) 2018-06-13 2023-01-11 Thinkcyte Inc Methods and systems for cytometry
EP3969978B1 (en) 2019-05-14 2025-10-01 University of Pittsburgh - of the Commonwealth System of Higher Education System and method for characterizing cellular phenotypic diversity from multi-parameter cellular. and sub-cellular imaging data
JP7556557B2 (ja) 2019-12-27 2024-09-26 シンクサイト株式会社 フローサイトメータ性能評価方法
WO2021200960A1 (ja) 2020-04-01 2021-10-07 シンクサイト株式会社 観察装置
CN121476024A (zh) 2020-04-01 2026-02-06 兴科尚株式会社 流式细胞仪
EP4189065A4 (en) * 2020-07-30 2024-08-28 Allen Institute SYSTEMS, DEVICES AND METHODS FOR SCREENING COMPOUNDS USING PREDICTIVE LABELING
WO2023009513A1 (en) 2021-07-26 2023-02-02 Asedasciences Ag Improved methods for identification of functional cell states
WO2023056481A1 (en) * 2021-10-01 2023-04-06 CAP Diagnostics, LLC, dba Pathnostics Automated methods and systems for rapid identification of target particles
US12105081B2 (en) 2021-10-20 2024-10-01 Travera, Inc. Treatment response assessment using normalized single cell measurements
KR20250139846A (ko) 2023-01-23 2025-09-23 아세다사이언시즈 아게 향상된 인간-컴퓨터 상호작용 시스템

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AU6024294A (en) * 1993-01-08 1994-08-15 Coulter Corporation Method of using preserved control cells in the calibration of fluorescent and light scatter measurements
CA2196496A1 (en) 1997-01-31 1998-07-31 Stephen William Watson Michnick Protein fragment complementation assay for the detection of protein-protein interactions
US20050221280A1 (en) * 1998-02-02 2005-10-06 Odyssey Thera, Inc. Protein-protein interactions for pharmacological profiling
US7166424B2 (en) 1998-02-02 2007-01-23 Odyssey Thera Inc. Fragments of fluorescent proteins for protein fragment complementation assays
US6801859B1 (en) 1998-12-23 2004-10-05 Rosetta Inpharmatics Llc Methods of characterizing drug activities using consensus profiles
US6998249B1 (en) * 1999-09-27 2006-02-14 Pharmacia & Upjohn Company Toxicity screening method
ATE516497T1 (de) 2000-03-06 2011-07-15 Asterand Acquisition Llc Screening für funktionshomologien
US6834237B2 (en) 2000-06-02 2004-12-21 Medicometrics Aps Method and system for classifying a biological sample
US7146349B2 (en) 2000-11-06 2006-12-05 International Business Machines Corporation Network for describing multimedia information
EP1620722A4 (en) 2003-04-23 2008-01-30 Bioseek Inc METHODS FOR CHARACTERIZING SIGNALING PATHWAYS AND COMPOUNDS INTERACTING THEREWITH
WO2004094992A2 (en) * 2003-04-23 2004-11-04 Bioseek, Inc. Methods for analysis of biological dataset profiles
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Also Published As

Publication number Publication date
AU2015206520B2 (en) 2021-07-22
US11137388B2 (en) 2021-10-05
DK3094974T3 (da) 2019-05-27
JP2017505140A (ja) 2017-02-16
AU2021204419A1 (en) 2021-07-22
SG11201705495XA (en) 2017-08-30
IL246734B (en) 2019-06-30
HK1231553A1 (en) 2017-12-22
US11867690B2 (en) 2024-01-09
WO2015109003A1 (en) 2015-07-23
KR102413041B1 (ko) 2022-06-23
EP3094974B1 (en) 2019-02-27
JP6606100B2 (ja) 2019-11-13
CA2972960A1 (en) 2015-07-23
US20150198584A1 (en) 2015-07-16
EP3094974A1 (en) 2016-11-23
ES2728119T3 (es) 2019-10-22
KR20160110444A (ko) 2016-09-21
US20210364499A1 (en) 2021-11-25
AU2015206520A1 (en) 2016-07-14
US20160370350A1 (en) 2016-12-22
IL246734A0 (en) 2016-08-31

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