CA2964069A1 - Universal blocking oligo system and improved hybridization capture methods for multiplexed capture reactions - Google Patents
Universal blocking oligo system and improved hybridization capture methods for multiplexed capture reactions Download PDFInfo
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- CA2964069A1 CA2964069A1 CA2964069A CA2964069A CA2964069A1 CA 2964069 A1 CA2964069 A1 CA 2964069A1 CA 2964069 A CA2964069 A CA 2964069A CA 2964069 A CA2964069 A CA 2964069A CA 2964069 A1 CA2964069 A1 CA 2964069A1
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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Applications Claiming Priority (5)
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| US201462062612P | 2014-10-10 | 2014-10-10 | |
| US201462062616P | 2014-10-10 | 2014-10-10 | |
| US62/062,612 | 2014-10-10 | ||
| US62/062,616 | 2014-10-10 | ||
| PCT/IB2015/057679 WO2016055956A1 (en) | 2014-10-10 | 2015-10-08 | Universal blocking oligo system and improved hybridization capture methods for multiplexed capture reactions |
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| CA2964069A1 true CA2964069A1 (en) | 2016-04-14 |
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| CA2964069A Abandoned CA2964069A1 (en) | 2014-10-10 | 2015-10-08 | Universal blocking oligo system and improved hybridization capture methods for multiplexed capture reactions |
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| EP (1) | EP3204518B1 (OSRAM) |
| JP (1) | JP6722179B2 (OSRAM) |
| CN (1) | CN107109485B (OSRAM) |
| CA (1) | CA2964069A1 (OSRAM) |
| IL (1) | IL251661B (OSRAM) |
| WO (1) | WO2016055956A1 (OSRAM) |
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| KR102122632B1 (ko) | 2013-08-05 | 2020-06-16 | 트위스트 바이오사이언스 코포레이션 | 드 노보 합성된 유전자 라이브러리 |
| WO2016126882A1 (en) | 2015-02-04 | 2016-08-11 | Twist Bioscience Corporation | Methods and devices for de novo oligonucleic acid assembly |
| WO2016172377A1 (en) | 2015-04-21 | 2016-10-27 | Twist Bioscience Corporation | Devices and methods for oligonucleic acid library synthesis |
| EP3350314A4 (en) | 2015-09-18 | 2019-02-06 | Twist Bioscience Corporation | OLIGONUCLEIC ACID VARIANT LIBRARIES VARIANT AND SYNTHESIS THEREOF |
| CN108698012A (zh) | 2015-09-22 | 2018-10-23 | 特韦斯特生物科学公司 | 用于核酸合成的柔性基底 |
| CN108603307A (zh) | 2015-12-01 | 2018-09-28 | 特韦斯特生物科学公司 | 功能化表面及其制备 |
| GB2568444A (en) | 2016-08-22 | 2019-05-15 | Twist Bioscience Corp | De novo synthesized nucleic acid libraries |
| US10417457B2 (en) | 2016-09-21 | 2019-09-17 | Twist Bioscience Corporation | Nucleic acid based data storage |
| CN110366613A (zh) | 2016-12-16 | 2019-10-22 | 特韦斯特生物科学公司 | 免疫突触的变体文库及其合成 |
| SG11201907713WA (en) | 2017-02-22 | 2019-09-27 | Twist Bioscience Corp | Nucleic acid based data storage |
| CN110913865A (zh) | 2017-03-15 | 2020-03-24 | 特韦斯特生物科学公司 | 免疫突触的变体文库及其合成 |
| WO2018231864A1 (en) | 2017-06-12 | 2018-12-20 | Twist Bioscience Corporation | Methods for seamless nucleic acid assembly |
| KR102784398B1 (ko) | 2017-06-12 | 2025-03-19 | 트위스트 바이오사이언스 코포레이션 | 심리스 핵산 어셈블리를 위한 방법 |
| JP2020536504A (ja) | 2017-09-11 | 2020-12-17 | ツイスト バイオサイエンス コーポレーション | Ｇｐｃｒ結合タンパク質およびその合成 |
| KR102889470B1 (ko) | 2017-10-20 | 2025-11-21 | 트위스트 바이오사이언스 코포레이션 | 폴리뉴클레오타이드 합성을 위한 가열된 나노웰 |
| WO2019136175A1 (en) | 2018-01-04 | 2019-07-11 | Twist Bioscience Corporation | Dna-based digital information storage |
| CA3100739A1 (en) | 2018-05-18 | 2019-11-21 | Twist Bioscience Corporation | Polynucleotides, reagents, and methods for nucleic acid hybridization |
| US20190365645A1 (en) | 2018-05-31 | 2019-12-05 | Massachusetts Institute Of Technology | Drug delivery articles for gram-level dosing |
| EP3837381A1 (en) * | 2018-08-15 | 2021-06-23 | Illumina, Inc. | Compositions and methods for improving library enrichment |
| CN119708086A (zh) | 2018-12-26 | 2025-03-28 | 特韦斯特生物科学公司 | 高度准确的从头多核苷酸合成 |
| CN113728100A (zh) * | 2019-02-25 | 2021-11-30 | 特韦斯特生物科学公司 | 用于下一代测序的组合物和方法 |
| AU2020227802A1 (en) | 2019-02-26 | 2021-10-14 | Twist Bioscience Corporation | Variant nucleic acid libraries for antibody optimization |
| EP3930753A4 (en) | 2019-02-26 | 2023-03-29 | Twist Bioscience Corporation | VARIANT NUCLEIC ACID LIBRARIES FOR GLP1 RECEPTOR |
| CN114729342A (zh) | 2019-06-21 | 2022-07-08 | 特韦斯特生物科学公司 | 基于条形码的核酸序列装配 |
| WO2020259678A1 (zh) * | 2019-06-26 | 2020-12-30 | 南京金斯瑞生物科技有限公司 | 一种含有阻断物的寡核苷酸 |
| AU2020355027A1 (en) | 2019-09-23 | 2022-04-21 | Twist Bioscience Corporation | Antibodies that bind CD3 Epsilon |
| WO2021061829A1 (en) | 2019-09-23 | 2021-04-01 | Twist Bioscience Corporation | Variant nucleic acid libraries for crth2 |
| US11718848B1 (en) * | 2020-05-29 | 2023-08-08 | Color Health, Inc. | Methods for depletion of high-copy sequences in multiplexed whole genome sequencing libraries |
| CN111961711A (zh) * | 2020-08-31 | 2020-11-20 | 伯科生物科技有限公司 | 用于靶向测序的通用杂交增强剂及方法 |
| WO2022187734A1 (en) * | 2021-03-05 | 2022-09-09 | Bioo Scientific Corporation | Improved universal blocking oligonucleotides for reduced off-target hybridization in hybridization capture methods |
| EP4409028A2 (en) * | 2021-09-30 | 2024-08-07 | Illumina, Inc. | Blocker methods |
| WO2024092562A1 (zh) * | 2022-11-02 | 2024-05-10 | 京东方科技集团股份有限公司 | 一种封闭序列及其试剂盒和使用方法 |
| CN116200477A (zh) * | 2022-12-13 | 2023-06-02 | 成都齐碳科技有限公司 | 包含联合阻滞元件的衔接体、构建体、方法和应用 |
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| GB0324456D0 (en) | 2003-10-20 | 2003-11-19 | Isis Innovation | Parallel DNA sequencing methods |
| US20140243232A1 (en) * | 2011-07-14 | 2014-08-28 | Life Technologies Corporation | Nucleic acid complexity reduction |
| CA2877740A1 (en) * | 2012-07-03 | 2014-01-09 | Integrated Dna Technologies, Inc. | Tm-enhanced blocking oligonucleotides and baits for improved target enrichment and reduced off-target selection |
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2015
- 2015-10-08 CN CN201580066291.7A patent/CN107109485B/zh not_active Expired - Fee Related
- 2015-10-08 CA CA2964069A patent/CA2964069A1/en not_active Abandoned
- 2015-10-08 US US15/514,957 patent/US10648103B2/en active Active
- 2015-10-08 JP JP2017519306A patent/JP6722179B2/ja not_active Expired - Fee Related
- 2015-10-08 EP EP15849044.1A patent/EP3204518B1/en not_active Not-in-force
- 2015-10-08 WO PCT/IB2015/057679 patent/WO2016055956A1/en not_active Ceased
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2017
- 2017-04-09 IL IL251661A patent/IL251661B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP6722179B2 (ja) | 2020-07-15 |
| CN107109485A (zh) | 2017-08-29 |
| IL251661A0 (en) | 2017-06-29 |
| US10648103B2 (en) | 2020-05-12 |
| EP3204518A1 (en) | 2017-08-16 |
| CN107109485B (zh) | 2020-12-08 |
| IL251661B (en) | 2021-12-01 |
| US20170218537A1 (en) | 2017-08-03 |
| EP3204518B1 (en) | 2019-07-10 |
| JP2017537609A (ja) | 2017-12-21 |
| EP3204518A4 (en) | 2018-03-21 |
| WO2016055956A1 (en) | 2016-04-14 |
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