CA2963602A1 - Schema posologique d'il-2 variables multiples pour le traitement de troubles immunitaires - Google Patents
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
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- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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- A61K39/461—Cellular immunotherapy characterised by the cell type used
- A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
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- A61K39/462—Cellular immunotherapy characterized by the effect or the function of the cells
- A61K39/4621—Cellular immunotherapy characterized by the effect or the function of the cells immunosuppressive or immunotolerising
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- A61K39/4643—Vertebrate antigens
- A61K39/46434—Antigens related to induction of tolerance to non-self
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
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- A—HUMAN NECESSITIES
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- A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the cancer treated
- A61K2239/48—Blood cells, e.g. leukemia or lymphoma
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- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
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Abstract
La présente invention est basée, en partie, sur l'identification de méthodes d'utilisation de doses d'IL-2 variables multiples pour identifier, évaluer, prévenir, et traiter des troubles immunitaires.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462061952P | 2014-10-09 | 2014-10-09 | |
| US62/061,952 | 2014-10-09 | ||
| PCT/US2015/054466 WO2016057651A1 (fr) | 2014-10-09 | 2015-10-07 | Schéma posologique d'il-2 variables multiples pour le traitement de troubles immunitaires |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2963602A1 true CA2963602A1 (fr) | 2016-04-14 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2963602A Pending CA2963602A1 (fr) | 2014-10-09 | 2015-10-07 | Schema posologique d'il-2 variables multiples pour le traitement de troubles immunitaires |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US10806773B2 (fr) |
| EP (1) | EP3204119B1 (fr) |
| JP (1) | JP6941561B2 (fr) |
| CN (2) | CN107106876B (fr) |
| AU (1) | AU2015328163B2 (fr) |
| CA (1) | CA2963602A1 (fr) |
| WO (1) | WO2016057651A1 (fr) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4169524A1 (fr) * | 2021-10-25 | 2023-04-26 | Ellennbe GmbH | Substance immunomodulatrice pour utilisation dans un procédé de traitement et/ou de prévention d'une maladie |
| WO2023072877A1 (fr) * | 2021-10-25 | 2023-05-04 | Ellennbe Gmbh | Composition pharmaceutique et kit comprenant une substance immuno-modulatrice pour traiter des maladies |
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| PL3482766T3 (pl) | 2014-08-11 | 2020-11-16 | Delinia, Inc. | Modyfikowane warianty il-2, które selektywnie aktywują limfocyty t regulatorowe do leczenia chorób autoimmunologicznych |
| US20170204154A1 (en) | 2016-01-20 | 2017-07-20 | Delinia, Inc. | Molecules that selectively activate regulatory t cells for the treatment of autoimmune diseases |
| WO2018089420A1 (fr) | 2016-11-08 | 2018-05-17 | Delinia, Inc. | Variants d'il-2 pour le traitement de maladies auto-immunes |
| EP3595440A2 (fr) * | 2017-03-14 | 2020-01-22 | Juno Therapeutics, Inc. | Procédés de stockage cryogénique |
| JP2020028278A (ja) * | 2018-08-24 | 2020-02-27 | 国立大学法人九州大学 | 被検体に生じるイベントを予測するための判別器の生成方法、及び前記判別器を用いた被検体の層別化方法 |
| US20220370563A1 (en) * | 2019-10-25 | 2022-11-24 | Neoleukin Therapeutics, Inc. | Methods of administration of il-2 receptor agonists |
| WO2022109477A1 (fr) * | 2020-11-23 | 2022-05-27 | University Of Florida Research Foundation, Incorporated | Utilisation de facteurs de croissance de type insuline avec des cytokines à chaîne gamma pour induire une prolifération homéostatique de lymphocytes |
| EP4016078A1 (fr) * | 2020-12-18 | 2022-06-22 | Rheinische Friedrich-Wilhelms-Universität Bonn | Procédé utile dans la thérapie d'induction de tolérance et kits correspondants |
| WO2023081320A1 (fr) * | 2021-11-04 | 2023-05-11 | Orca Biosystems, Inc. | Compositions thérapeutiques et procédés de transplantation de cellules souches hématopoïétiques allogéniques |
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2015
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- 2015-10-07 CN CN201580067147.5A patent/CN107106876B/zh active Active
- 2015-10-07 AU AU2015328163A patent/AU2015328163B2/en active Active
- 2015-10-07 CN CN202110564807.8A patent/CN113230384A/zh active Pending
- 2015-10-07 EP EP15849237.1A patent/EP3204119B1/fr active Active
- 2015-10-07 US US15/516,775 patent/US10806773B2/en active Active
- 2015-10-07 JP JP2017518533A patent/JP6941561B2/ja active Active
- 2015-10-07 CA CA2963602A patent/CA2963602A1/fr active Pending
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4169524A1 (fr) * | 2021-10-25 | 2023-04-26 | Ellennbe GmbH | Substance immunomodulatrice pour utilisation dans un procédé de traitement et/ou de prévention d'une maladie |
| WO2023072877A1 (fr) * | 2021-10-25 | 2023-05-04 | Ellennbe Gmbh | Composition pharmaceutique et kit comprenant une substance immuno-modulatrice pour traiter des maladies |
| WO2023072864A1 (fr) * | 2021-10-25 | 2023-05-04 | Ellennbe Gmbh | Composition pharmaceutique et kit comprenant une substance immunomodulatrice pour le traitement de maladies |
| WO2023072856A1 (fr) * | 2021-10-25 | 2023-05-04 | Ellennbe Gmbh | Composition pharmaceutique et kit comprenant une substance immunomodulatrice pour le traitement de maladies |
| WO2023072870A1 (fr) * | 2021-10-25 | 2023-05-04 | Ellennbe Gmbh | Composition pharmaceutique et kit correspondant comprenant une substance immunomodulatrice pour le traitement de maladies |
| WO2023072863A1 (fr) * | 2021-10-25 | 2023-05-04 | Ellennbe Gmbh | Composition pharmaceutique et kit comprenant une subtance immuno-modulatrice pour le traitement de maladies |
| WO2023072853A1 (fr) * | 2021-10-25 | 2023-05-04 | Ellennbe Gmbh | Forme posologique injectable et kit comprenant une substance immunomodulatrice pour le traitement de maladies |
| WO2023072857A1 (fr) * | 2021-10-25 | 2023-05-04 | Ellennbe Gmbh | Composition pharmaceutique et kit comprenant une substance immunomodulatrice pour le traitement de maladies |
| WO2023072859A1 (fr) * | 2021-10-25 | 2023-05-04 | Ellennbe Gmbh | Composition pharmaceutique et kit comprenant une substance immunomodulatrice pour le traitement de maladies |
| WO2023072861A1 (fr) * | 2021-10-25 | 2023-05-04 | Ellennbe Gmbh | Composition pharmaceutique et kit comprenant une substance immunomodulatrice pour le traitement de maladies |
| WO2023072871A1 (fr) * | 2021-10-25 | 2023-05-04 | Ellennbe Gmbh | Utilisation combinée de substances immunomodulatrices et de cellules mononucléaires du sang périphérique pour le traitement et/ou la prévention d'une maladie inflammatoire, d'une maladie immunologique et/ou d'une maladie auto-immunologique |
| WO2023072850A1 (fr) * | 2021-10-25 | 2023-05-04 | Ellennbe Gmbh | Compositions pharmaceutiques comprenant une subtance immuno-modulatrice pour le traitement de maladies |
| WO2023072858A1 (fr) * | 2021-10-25 | 2023-05-04 | Ellennbe Gmbh | Composition pharmaceutique et kit comprenant une substance immunomodulatrice pour le traitement de maladies |
| WO2023072854A1 (fr) * | 2021-10-25 | 2023-05-04 | Ellennbe Gmbh | Forme galénique injectable et kit comprenant une substance immunomodulatrice pour le traitement de maladies |
| WO2023072865A1 (fr) * | 2021-10-25 | 2023-05-04 | Ellennbe Gmbh | Composition pharmaceutique et kit correspondant comprenant une substance immunomodulatrice pour le traitement de maladies |
| WO2023072852A1 (fr) * | 2021-10-25 | 2023-05-04 | Ellennbe Gmbh | Composition pharmaceutique et kit comprenant une substance immunomodulatrice pour le traitement de maladies |
| WO2024084038A1 (fr) * | 2022-10-20 | 2024-04-25 | Ellennbe Gmbh | Technologie de plateforme pour le traitement de maladies inflammatoires, immunologiques et/ou auto-immunologiques |
Also Published As
| Publication number | Publication date |
|---|---|
| CN113230384A (zh) | 2021-08-10 |
| WO2016057651A1 (fr) | 2016-04-14 |
| JP2018500276A (ja) | 2018-01-11 |
| AU2015328163A1 (en) | 2017-05-04 |
| CN107106876A (zh) | 2017-08-29 |
| AU2015328163B2 (en) | 2020-10-15 |
| US20210077580A1 (en) | 2021-03-18 |
| EP3204119A4 (fr) | 2018-06-20 |
| US10806773B2 (en) | 2020-10-20 |
| JP6941561B2 (ja) | 2021-09-29 |
| US20170348391A1 (en) | 2017-12-07 |
| EP3204119B1 (fr) | 2021-06-09 |
| CN107106876B (zh) | 2021-06-11 |
| EP3204119A1 (fr) | 2017-08-16 |
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