CA2953452A1 - Analyte concentration measurement - Google Patents
Analyte concentration measurement Download PDFInfo
- Publication number
- CA2953452A1 CA2953452A1 CA2953452A CA2953452A CA2953452A1 CA 2953452 A1 CA2953452 A1 CA 2953452A1 CA 2953452 A CA2953452 A CA 2953452A CA 2953452 A CA2953452 A CA 2953452A CA 2953452 A1 CA2953452 A1 CA 2953452A1
- Authority
- CA
- Canada
- Prior art keywords
- potential
- cycle
- mediator
- concentration
- test meter
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000005259 measurement Methods 0.000 title claims abstract description 30
- 239000012491 analyte Substances 0.000 title claims abstract description 21
- 238000009825 accumulation Methods 0.000 claims abstract description 31
- 238000006479 redox reaction Methods 0.000 claims abstract description 30
- 238000000034 method Methods 0.000 claims abstract description 28
- 239000008364 bulk solution Substances 0.000 claims abstract description 13
- 230000007423 decrease Effects 0.000 claims abstract description 11
- 238000012360 testing method Methods 0.000 claims description 31
- 230000003647 oxidation Effects 0.000 claims description 24
- 238000007254 oxidation reaction Methods 0.000 claims description 24
- 230000009467 reduction Effects 0.000 claims description 22
- 230000000977 initiatory effect Effects 0.000 claims description 17
- 238000009792 diffusion process Methods 0.000 abstract description 11
- 230000000694 effects Effects 0.000 abstract description 7
- 230000002452 interceptive effect Effects 0.000 abstract description 3
- 238000005534 hematocrit Methods 0.000 abstract description 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 19
- 239000008103 glucose Substances 0.000 description 19
- 238000006243 chemical reaction Methods 0.000 description 15
- 230000035945 sensitivity Effects 0.000 description 14
- 210000004369 blood Anatomy 0.000 description 7
- 239000008280 blood Substances 0.000 description 7
- 230000000116 mitigating effect Effects 0.000 description 7
- 238000013459 approach Methods 0.000 description 4
- 230000001419 dependent effect Effects 0.000 description 4
- 210000004027 cell Anatomy 0.000 description 3
- 239000003153 chemical reaction reagent Substances 0.000 description 3
- 230000003247 decreasing effect Effects 0.000 description 3
- 238000000926 separation method Methods 0.000 description 3
- 102000004190 Enzymes Human genes 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 239000013543 active substance Substances 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000012937 correction Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 238000000840 electrochemical analysis Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 210000003743 erythrocyte Anatomy 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 230000036571 hydration Effects 0.000 description 1
- 238000006703 hydration reaction Methods 0.000 description 1
- 238000009533 lab test Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 230000037361 pathway Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 239000000376 reactant Substances 0.000 description 1
- 238000011946 reduction process Methods 0.000 description 1
- 230000010076 replication Effects 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
- G01N27/3274—Corrective measures, e.g. error detection, compensation for temperature or hematocrit, calibration
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Electrochemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1412156.0 | 2014-07-08 | ||
| GBGB1412156.0A GB201412156D0 (en) | 2014-07-08 | 2014-07-08 | Analyte concentration measurement |
| PCT/GB2015/051973 WO2016005743A1 (en) | 2014-07-08 | 2015-07-08 | Analyte concentration measurement |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2953452A1 true CA2953452A1 (en) | 2016-01-14 |
Family
ID=51410820
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2953452A Abandoned CA2953452A1 (en) | 2014-07-08 | 2015-07-08 | Analyte concentration measurement |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP3167282A1 (zh) |
| JP (1) | JP6619367B2 (zh) |
| KR (1) | KR20170028408A (zh) |
| CN (1) | CN106687803A (zh) |
| AU (1) | AU2015287447A1 (zh) |
| BR (1) | BR112017000305A2 (zh) |
| CA (1) | CA2953452A1 (zh) |
| GB (1) | GB201412156D0 (zh) |
| RU (1) | RU2680266C2 (zh) |
| WO (1) | WO2016005743A1 (zh) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108350408B (zh) | 2015-08-25 | 2022-12-16 | 阿威尔斯医疗公司 | 用于检测流体样品中有活力的微生物的设备、系统和方法 |
| US10174356B2 (en) | 2016-05-31 | 2019-01-08 | Avails Medical, Inc. | Devices, systems and methods to detect viable infectious agents in a fluid sample and susceptibility of infectious agents to anti-infectives |
| US20180306744A1 (en) * | 2017-04-20 | 2018-10-25 | Lifescan Scotland Limited | Analyte measurement system and method |
| WO2019005296A1 (en) | 2017-06-27 | 2019-01-03 | Avails Medical, Inc. | APPARATUS, SYSTEMS AND METHODS FOR DETERMINING THE SENSITIVITY OF MICROORGANISMS TO ANTI-INFECTIOUS |
| JP7209701B2 (ja) * | 2017-10-03 | 2023-01-20 | アベイルズ メディカル，インコーポレイテッド | レドックス反応に基づいて微生物の濃度及び抗感染剤に対する微生物の感受性を決定する装置、システム、及び方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7455975B2 (en) * | 2000-04-14 | 2008-11-25 | Esa Biosciences, Inc. | Electrochemical detection of nucleic acid sequences |
| RU2267120C2 (ru) * | 2000-07-14 | 2005-12-27 | Лайфскен, Инк. | Электрохимический способ измерения скоростей химических реакций |
| GB0211449D0 (en) * | 2002-05-17 | 2002-06-26 | Oxford Biosensors Ltd | Analyte measurement |
| GB2428484B (en) * | 2004-01-29 | 2008-09-10 | Siemens Ag | Method for measuring the concentration or change in concentration of a redox-active substance and associated device |
| CN103901092B (zh) * | 2004-05-14 | 2016-07-06 | 拜尔健康护理有限责任公司 | 检测生物分析物的伏安测量系统 |
| US7749371B2 (en) * | 2005-09-30 | 2010-07-06 | Lifescan, Inc. | Method and apparatus for rapid electrochemical analysis |
| ES2397663T3 (es) * | 2006-10-05 | 2013-03-08 | Lifescan Scotland Limited | Sistemas y procedimientos para determinar una concentración de un analito sustancialmente independiente del hematocrito |
| US8603768B2 (en) * | 2008-01-17 | 2013-12-10 | Lifescan, Inc. | System and method for measuring an analyte in a sample |
| WO2012012341A1 (en) * | 2010-07-19 | 2012-01-26 | Cilag Gmbh International | System and method for measuring an analyte in a sample |
| US9201038B2 (en) * | 2012-07-24 | 2015-12-01 | Lifescan Scotland Limited | System and methods to account for interferents in a glucose biosensor |
| US9005426B2 (en) * | 2012-09-28 | 2015-04-14 | Cilag Gmbh International | System and method for determining hematocrit insensitive glucose concentration |
| GB2515299B (en) * | 2013-06-18 | 2015-12-30 | Suresensors Ltd | Methods and apparatus for determining analyte in a sample |
-
2014
- 2014-07-08 GB GBGB1412156.0A patent/GB201412156D0/en not_active Ceased
-
2015
- 2015-07-08 BR BR112017000305A patent/BR112017000305A2/pt not_active Application Discontinuation
- 2015-07-08 EP EP15747510.4A patent/EP3167282A1/en not_active Withdrawn
- 2015-07-08 CA CA2953452A patent/CA2953452A1/en not_active Abandoned
- 2015-07-08 AU AU2015287447A patent/AU2015287447A1/en not_active Abandoned
- 2015-07-08 KR KR1020177003207A patent/KR20170028408A/ko unknown
- 2015-07-08 CN CN201580037065.6A patent/CN106687803A/zh active Pending
- 2015-07-08 JP JP2016573879A patent/JP6619367B2/ja not_active Expired - Fee Related
- 2015-07-08 RU RU2017103730A patent/RU2680266C2/ru not_active IP Right Cessation
- 2015-07-08 WO PCT/GB2015/051973 patent/WO2016005743A1/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| EP3167282A1 (en) | 2017-05-17 |
| WO2016005743A1 (en) | 2016-01-14 |
| KR20170028408A (ko) | 2017-03-13 |
| GB201412156D0 (en) | 2014-08-20 |
| RU2017103730A (ru) | 2018-08-08 |
| JP2017519990A (ja) | 2017-07-20 |
| JP6619367B2 (ja) | 2019-12-11 |
| RU2680266C2 (ru) | 2019-02-19 |
| AU2015287447A1 (en) | 2016-12-22 |
| CN106687803A (zh) | 2017-05-17 |
| RU2017103730A3 (zh) | 2019-01-14 |
| BR112017000305A2 (pt) | 2017-10-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |
Effective date: 20211123 |
|
| FZDE | Discontinued |
Effective date: 20211123 |