CA2951420A1 - Methods for treating pruritus - Google Patents
Methods for treating pruritus Download PDFInfo
- Publication number
- CA2951420A1 CA2951420A1 CA2951420A CA2951420A CA2951420A1 CA 2951420 A1 CA2951420 A1 CA 2951420A1 CA 2951420 A CA2951420 A CA 2951420A CA 2951420 A CA2951420 A CA 2951420A CA 2951420 A1 CA2951420 A1 CA 2951420A1
- Authority
- CA
- Canada
- Prior art keywords
- day
- nalbuphine
- pruritus
- sustained release
- dose
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
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| US201462011936P | 2014-06-13 | 2014-06-13 | |
| US62/011,936 | 2014-06-13 | ||
| PCT/US2015/035650 WO2015192071A1 (en) | 2014-06-13 | 2015-06-12 | Methods for treating pruritus |
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| US20140179727A1 (en) | 2012-12-14 | 2014-06-26 | Trevi Therapeutics, Inc. | Methods for treating pruritus |
| US20170216277A1 (en) * | 2016-01-06 | 2017-08-03 | Trevi Therapeutics, Inc. | Therapeutic use of nalbuphine without aquaretic effects |
| AU2017238051B9 (en) * | 2016-03-21 | 2022-11-03 | Trevi Therapeutics, Inc. | Treatment of uremic pruritus |
| BR112019008241A2 (pt) * | 2016-10-25 | 2019-07-16 | Trevi Therapeutics Inc | tratamento do prurigo nodular |
| CN112040948A (zh) * | 2018-03-29 | 2020-12-04 | 顺天医药生技股份有限公司 | 治疗瘙痒的组合物和方法 |
| CN112672743A (zh) * | 2018-07-11 | 2021-04-16 | 特雷维治疗股份有限公司 | 肝病瘙痒症状的治疗 |
| IL318587A (en) * | 2018-07-23 | 2025-03-01 | Trevi Therapeutics Inc | Treatment of chronic cough, shortness of breath and wheezing |
| IL294601A (en) | 2020-01-10 | 2022-09-01 | Trevi Therapeutics Inc | Methods of administration of nalbuphine |
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| PT1931315E (pt) * | 2005-08-24 | 2014-01-03 | Endo Pharmaceuticals Inc | Formulações de libertação sustentada de nalbufina |
| EP2150247B1 (en) * | 2007-04-23 | 2012-10-31 | Symrise AG | Polyethylene glycol esters and cosmetic and/or dermatological preparations |
| US8987289B2 (en) * | 2012-12-14 | 2015-03-24 | Trevi Therapeutics, Inc. | Methods for treating pruritus |
| US20140179727A1 (en) * | 2012-12-14 | 2014-06-26 | Trevi Therapeutics, Inc. | Methods for treating pruritus |
| US8637538B1 (en) * | 2012-12-14 | 2014-01-28 | Trevi Therapeutics, Inc. | Methods for treatment of pruritis |
| EP2931279B1 (en) * | 2012-12-14 | 2024-03-20 | Trevi Therapeutics, Inc. | Methods for treating pruritus |
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| EP3154546A4 (en) | 2018-01-10 |
| US20150359789A1 (en) | 2015-12-17 |
| KR20170016983A (ko) | 2017-02-14 |
| MX2016016404A (es) | 2017-11-30 |
| RU2017101102A (ru) | 2018-07-16 |
| EP3154546A1 (en) | 2017-04-19 |
| WO2015192071A1 (en) | 2015-12-17 |
| AU2015274327A1 (en) | 2017-01-05 |
| IL249475A0 (en) | 2017-02-28 |
| US20190099416A1 (en) | 2019-04-04 |
| BR112016029236A2 (pt) | 2017-11-07 |
| JP2017517553A (ja) | 2017-06-29 |
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