CN106535897A - 用于治疗瘙痒的方法 - Google Patents

用于治疗瘙痒的方法 Download PDF

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Publication number
CN106535897A
CN106535897A CN201580039250.9A CN201580039250A CN106535897A CN 106535897 A CN106535897 A CN 106535897A CN 201580039250 A CN201580039250 A CN 201580039250A CN 106535897 A CN106535897 A CN 106535897A
Authority
CN
China
Prior art keywords
day
nalbuphine
dose
weight
sustained release
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201580039250.9A
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English (en)
Chinese (zh)
Inventor
T·夏夏
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Trevi Therapeutics Inc
Original Assignee
Trevi Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Trevi Therapeutics Inc filed Critical Trevi Therapeutics Inc
Publication of CN106535897A publication Critical patent/CN106535897A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/08—Antiseborrheics

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CN201580039250.9A 2014-06-13 2015-06-12 用于治疗瘙痒的方法 Pending CN106535897A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462011936P 2014-06-13 2014-06-13
US62/011,936 2014-06-13
PCT/US2015/035650 WO2015192071A1 (en) 2014-06-13 2015-06-12 Methods for treating pruritus

Publications (1)

Publication Number Publication Date
CN106535897A true CN106535897A (zh) 2017-03-22

Family

ID=54834447

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201580039250.9A Pending CN106535897A (zh) 2014-06-13 2015-06-12 用于治疗瘙痒的方法

Country Status (12)

Country Link
US (2) US20150359789A1 (enExample)
EP (1) EP3154546A4 (enExample)
JP (1) JP2017517553A (enExample)
KR (1) KR20170016983A (enExample)
CN (1) CN106535897A (enExample)
AU (1) AU2015274327A1 (enExample)
BR (1) BR112016029236A2 (enExample)
CA (1) CA2951420A1 (enExample)
IL (1) IL249475A0 (enExample)
MX (1) MX2016016404A (enExample)
RU (1) RU2017101102A (enExample)
WO (1) WO2015192071A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112040948A (zh) * 2018-03-29 2020-12-04 顺天医药生技股份有限公司 治疗瘙痒的组合物和方法
CN112672743A (zh) * 2018-07-11 2021-04-16 特雷维治疗股份有限公司 肝病瘙痒症状的治疗

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140179727A1 (en) 2012-12-14 2014-06-26 Trevi Therapeutics, Inc. Methods for treating pruritus
US20170216277A1 (en) * 2016-01-06 2017-08-03 Trevi Therapeutics, Inc. Therapeutic use of nalbuphine without aquaretic effects
US20180008592A1 (en) * 2016-03-21 2018-01-11 Trevi Therapeutics, Inc. Treatment of uremic pruritus
AU2017350852A1 (en) * 2016-10-25 2019-04-11 Trevi Therapeutics, Inc. Treatment of prurigo nodularis
MX2021000908A (es) 2018-07-23 2021-06-08 Trevi Therapeutics Inc Tratamiento de la tos cronica, la dificultad respiratoria y la disnea.
MX2022008554A (es) 2020-01-10 2022-08-10 Trevi Therapeutics Inc Metodos de administracion de nalbufina.

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014093871A1 (en) * 2012-12-14 2014-06-19 Trevi Therapeutics, Inc. Methods for treating pruritus

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1931315E (pt) * 2005-08-24 2014-01-03 Endo Pharmaceuticals Inc Formulações de libertação sustentada de nalbufina
US8394812B2 (en) * 2005-08-24 2013-03-12 Penwest Pharmaceuticals Co. Sustained release formulations of nalbuphine
WO2008128892A1 (en) * 2007-04-23 2008-10-30 Symrise Gmbh & Co. Kg Polyethylene glycol esters and cosmetic and/or dermatological preparations
US20140179727A1 (en) * 2012-12-14 2014-06-26 Trevi Therapeutics, Inc. Methods for treating pruritus
US8637538B1 (en) * 2012-12-14 2014-01-28 Trevi Therapeutics, Inc. Methods for treatment of pruritis
US8987289B2 (en) * 2012-12-14 2015-03-24 Trevi Therapeutics, Inc. Methods for treating pruritus

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014093871A1 (en) * 2012-12-14 2014-06-19 Trevi Therapeutics, Inc. Methods for treating pruritus

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112040948A (zh) * 2018-03-29 2020-12-04 顺天医药生技股份有限公司 治疗瘙痒的组合物和方法
CN112672743A (zh) * 2018-07-11 2021-04-16 特雷维治疗股份有限公司 肝病瘙痒症状的治疗

Also Published As

Publication number Publication date
EP3154546A4 (en) 2018-01-10
US20190099416A1 (en) 2019-04-04
MX2016016404A (es) 2017-11-30
KR20170016983A (ko) 2017-02-14
IL249475A0 (en) 2017-02-28
US20150359789A1 (en) 2015-12-17
WO2015192071A1 (en) 2015-12-17
JP2017517553A (ja) 2017-06-29
RU2017101102A3 (enExample) 2019-01-28
AU2015274327A1 (en) 2017-01-05
RU2017101102A (ru) 2018-07-16
BR112016029236A2 (pt) 2017-11-07
CA2951420A1 (en) 2015-12-17
EP3154546A1 (en) 2017-04-19

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