CA2947660C - Anti-b7-h3 antibodies and diagnostic uses thereof - Google Patents
Anti-b7-h3 antibodies and diagnostic uses thereof Download PDFInfo
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- G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
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- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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Landscapes
- Health & Medical Sciences (AREA)
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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| US201462082681P | 2014-11-21 | 2014-11-21 | |
| US62/082,681 | 2014-11-21 | ||
| PCT/EP2015/061777 WO2015181267A1 (en) | 2014-05-29 | 2015-05-28 | Anti-b7-h3 antibodies and diagnostic uses thereof |
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| US10899837B2 (en) | 2017-03-31 | 2021-01-26 | Jiangsu Hengrui Medicine Co., Ltd. | B7-H3 antibody, antigen-binding fragment thereof and medical use thereof |
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| WO2020018964A1 (en) | 2018-07-20 | 2020-01-23 | Fred Hutchinson Cancer Research Center | Compositions and methods for controlled expression of antigen-specific receptors |
| US12331110B2 (en) | 2018-09-05 | 2025-06-17 | The Board Of Regents Of The University Of Texas System | Monoclonal antibodies against endotrophin and the use thereof |
| WO2020076970A1 (en) * | 2018-10-11 | 2020-04-16 | Inhibrx, Inc. | B7h3 single domain antibodies and therapeutic compositions thereof |
| JP7682789B2 (ja) * | 2018-11-16 | 2025-05-26 | アルバート アインシュタイン カレッジ オブ メディスン | Ｂ７－Ｈ３のＩｇＶドメインに対するモノクローナル抗体及びその使用 |
| CN109851673B (zh) * | 2019-01-22 | 2023-07-25 | 苏州旭光科星抗体生物科技有限公司 | 一种抗人b7-h3单克隆抗体的制备方法及其免疫组化检测方法及其应用及其试剂盒 |
| WO2020227159A2 (en) | 2019-05-03 | 2020-11-12 | Flagship Pioneering Innovations V, Inc. | Methods of modulating immune activity |
| US20220332829A1 (en) * | 2019-09-16 | 2022-10-20 | Nanjing Sanhome Pharmaceutical Co., Ltd. | Anti-b7-h3 antibody and application thereof |
| CN110642948B (zh) * | 2019-10-09 | 2021-06-29 | 达石药业(广东)有限公司 | B7-h3纳米抗体、其制备方法及用途 |
| US20230114107A1 (en) | 2019-12-17 | 2023-04-13 | Flagship Pioneering Innovations V, Inc. | Combination anti-cancer therapies with inducers of iron-dependent cellular disassembly |
| CN113754766A (zh) * | 2020-06-02 | 2021-12-07 | 明慧医药（上海）有限公司 | 抗b7-h3抗体及其制备和应用 |
| CA3184366A1 (en) | 2020-06-29 | 2022-01-06 | Darby Rye Schmidt | Viruses engineered to promote thanotransmission and their use in treating cancer |
| CN115279417B (zh) | 2021-02-09 | 2025-01-03 | 苏州宜联生物医药有限公司 | 生物活性物偶联物及其制备方法和用途 |
| WO2022203414A1 (ko) * | 2021-03-26 | 2022-09-29 | 세라노틱스(주) | B7-h3 항체 또는 이의 항원 결합 단편 및 이의 용도 |
| CA3214085A1 (en) | 2021-03-31 | 2022-10-06 | Darby Rye Schmidt | Thanotransmission polypeptides and their use in treating cancer |
| CA3224374A1 (en) | 2021-06-29 | 2023-01-05 | Flagship Pioneering Innovations V, Inc. | Immune cells engineered to promote thanotransmission and uses thereof |
| CN118715242A (zh) * | 2021-10-05 | 2024-09-27 | 得克萨斯州大学系统董事会 | 包含b7-h3结合多肽的组合物和方法 |
| WO2023086772A1 (en) | 2021-11-12 | 2023-05-19 | Xencor, Inc. | Bispecific antibodies that bind to b7h3 and nkg2d |
| CN114380910B (zh) * | 2022-01-07 | 2023-04-28 | 苏州旭光科星抗体生物科技有限公司 | 靶向人b7-h3分子的人源化单克隆抗体及其应用 |
| WO2023155808A1 (zh) | 2022-02-16 | 2023-08-24 | 苏州宜联生物医药有限公司 | 抗体-艾日布林或其衍生物的偶联物、其中间体、制备方法、药物组合物和用途 |
| WO2023177232A1 (ko) * | 2022-03-18 | 2023-09-21 | 세종대학교산학협력단 | 항 b7-h3 단일클론항체 및 이의 용도 |
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| CN114773477B (zh) * | 2022-06-23 | 2022-09-09 | 上海优替济生生物医药有限公司 | 抗b7-h3抗体及其用途 |
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| CN120787161A (zh) * | 2023-01-30 | 2025-10-14 | 德克萨斯大学体系董事会 | 对B7-H3的4Ig同种型具有选择性的抗体及其使用方法 |
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| ES2259270B1 (es) * | 2005-03-09 | 2007-11-01 | Consejo Superior De Investigaciones Cientificas | Metodo de diagnostico in vitro de la enfermedad de alzheimer mediante un anticuerpo monoclonal. |
| CA2729593A1 (en) * | 2009-02-20 | 2010-08-26 | John Wayne Cancer Institute | B7-h3 as a biomarker for diagnosing the progression and early lymph node metastasis of cancer |
| CN101959216B (zh) | 2009-07-20 | 2014-06-18 | 电信科学技术研究院 | 一种分载波配置增强cell_fach的方法、系统和设备 |
| EP2982380B1 (en) * | 2010-03-04 | 2021-09-01 | MacroGenics, Inc. | Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof |
| PH12012501751A1 (en) * | 2010-03-04 | 2012-11-12 | Macrogenics Inc | Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof |
| KR20130043104A (ko) * | 2010-04-06 | 2013-04-29 | 카리스 라이프 사이언스 룩셈부르크 홀딩스 | 질병용 순환 생물학적 지표들 |
| AU2011291599B2 (en) * | 2010-08-18 | 2015-09-10 | Caris Life Sciences Switzerland Holdings Gmbh | Circulating biomarkers for disease |
| ES2667568T3 (es) * | 2011-04-25 | 2018-05-11 | Daiichi Sankyo Company, Limited | Anticuerpo anti-B7-H3 |
| JP6636016B2 (ja) * | 2014-05-29 | 2020-01-29 | スプリング バイオサイエンス コーポレーション | 抗ｂ７−ｈ３抗体及びその診断用途 |
-
2015
- 2015-05-28 JP JP2017514958A patent/JP6636016B2/ja active Active
- 2015-05-28 WO PCT/EP2015/061777 patent/WO2015181267A1/en not_active Ceased
- 2015-05-28 CA CA2947660A patent/CA2947660C/en active Active
- 2015-05-28 EP EP15724692.7A patent/EP3149040A1/en not_active Withdrawn
- 2015-05-28 AU AU2015265976A patent/AU2015265976B2/en active Active
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2016
- 2016-11-29 US US15/363,992 patent/US10501544B2/en active Active
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2019
- 2019-10-28 US US16/665,359 patent/US11525003B2/en active Active
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|---|---|
| AU2015265976B2 (en) | 2019-08-01 |
| JP6636016B2 (ja) | 2020-01-29 |
| EP3149040A1 (en) | 2017-04-05 |
| US20170073416A1 (en) | 2017-03-16 |
| WO2015181267A1 (en) | 2015-12-03 |
| CA2947660A1 (en) | 2015-12-03 |
| US11525003B2 (en) | 2022-12-13 |
| US10501544B2 (en) | 2019-12-10 |
| AU2015265976A1 (en) | 2016-10-13 |
| US20200048353A1 (en) | 2020-02-13 |
| JP2017524725A (ja) | 2017-08-31 |
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