CA2941689A1 - Article and method for detecting aerobic bacteria - Google Patents
Article and method for detecting aerobic bacteria Download PDFInfo
- Publication number
- CA2941689A1 CA2941689A1 CA2941689A CA2941689A CA2941689A1 CA 2941689 A1 CA2941689 A1 CA 2941689A1 CA 2941689 A CA2941689 A CA 2941689A CA 2941689 A CA2941689 A CA 2941689A CA 2941689 A1 CA2941689 A1 CA 2941689A1
- Authority
- CA
- Canada
- Prior art keywords
- sample
- hydrogel
- indicator
- substrate sheet
- detecting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000000034 method Methods 0.000 title claims abstract description 45
- 241001148470 aerobic bacillus Species 0.000 title abstract description 34
- 239000000203 mixture Substances 0.000 claims abstract description 220
- 239000000758 substrate Substances 0.000 claims abstract description 154
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 108
- 230000000694 effects Effects 0.000 claims abstract description 67
- 108090000371 Esterases Proteins 0.000 claims abstract description 15
- 108010031186 Glycoside Hydrolases Proteins 0.000 claims abstract description 14
- 102000005744 Glycoside Hydrolases Human genes 0.000 claims abstract description 14
- 108090000608 Phosphoric Monoester Hydrolases Proteins 0.000 claims abstract description 13
- 102000004160 Phosphoric Monoester Hydrolases Human genes 0.000 claims abstract description 13
- 125000000217 alkyl group Chemical group 0.000 claims abstract description 13
- 239000002824 redox indicator Substances 0.000 claims abstract description 11
- 239000000853 adhesive Substances 0.000 claims description 84
- 230000001070 adhesive effect Effects 0.000 claims description 84
- 239000000523 sample Substances 0.000 claims description 82
- 241000894006 Bacteria Species 0.000 claims description 70
- 235000015097 nutrients Nutrition 0.000 claims description 56
- 230000012010 growth Effects 0.000 claims description 49
- 239000007788 liquid Substances 0.000 claims description 46
- 102000004190 Enzymes Human genes 0.000 claims description 41
- 108090000790 Enzymes Proteins 0.000 claims description 41
- 239000003349 gelling agent Substances 0.000 claims description 33
- 239000012528 membrane Substances 0.000 claims description 33
- 244000005700 microbiome Species 0.000 claims description 30
- 239000000843 powder Substances 0.000 claims description 28
- 125000006853 reporter group Chemical group 0.000 claims description 28
- 230000001580 bacterial effect Effects 0.000 claims description 19
- 239000003153 chemical reaction reagent Substances 0.000 claims description 19
- 150000003839 salts Chemical class 0.000 claims description 16
- 238000004891 communication Methods 0.000 claims description 13
- 238000012258 culturing Methods 0.000 claims description 12
- 239000012530 fluid Substances 0.000 claims description 11
- HDTRYLNUVZCQOY-LIZSDCNHSA-N alpha,alpha-trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 claims description 9
- VMGAPWLDMVPYIA-HIDZBRGKSA-N n'-amino-n-iminomethanimidamide Chemical compound N\N=C\N=N VMGAPWLDMVPYIA-HIDZBRGKSA-N 0.000 claims description 9
- BOLDJAUMGUJJKM-LSDHHAIUSA-N renifolin D Natural products CC(=C)[C@@H]1Cc2c(O)c(O)ccc2[C@H]1CC(=O)c3ccc(O)cc3O BOLDJAUMGUJJKM-LSDHHAIUSA-N 0.000 claims description 9
- HDTRYLNUVZCQOY-UHFFFAOYSA-N α-D-glucopyranosyl-α-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)C(O)C(CO)O1 HDTRYLNUVZCQOY-UHFFFAOYSA-N 0.000 claims description 8
- 235000020183 skimmed milk Nutrition 0.000 claims description 8
- OPIFSICVWOWJMJ-HRNXZZBMSA-N 5-bromo-4-chloro-3-indolyl alpha-D-glucoside Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OC1=CNC2=CC=C(Br)C(Cl)=C12 OPIFSICVWOWJMJ-HRNXZZBMSA-N 0.000 claims description 7
- ODKSFYDXXFIFQN-BYPYZUCNSA-N L-arginine Chemical compound OC(=O)[C@@H](N)CCCN=C(N)N ODKSFYDXXFIFQN-BYPYZUCNSA-N 0.000 claims description 7
- 229930064664 L-arginine Natural products 0.000 claims description 7
- 235000014852 L-arginine Nutrition 0.000 claims description 7
- 150000001875 compounds Chemical class 0.000 claims description 6
- OPIFSICVWOWJMJ-AEOCFKNESA-N 5-bromo-4-chloro-3-indolyl beta-D-galactoside Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1OC1=CNC2=CC=C(Br)C(Cl)=C12 OPIFSICVWOWJMJ-AEOCFKNESA-N 0.000 claims description 4
- 125000003831 tetrazolyl group Chemical group 0.000 claims description 4
- QRXMUCSWCMTJGU-UHFFFAOYSA-L (5-bromo-4-chloro-1h-indol-3-yl) phosphate Chemical compound C1=C(Br)C(Cl)=C2C(OP([O-])(=O)[O-])=CNC2=C1 QRXMUCSWCMTJGU-UHFFFAOYSA-L 0.000 claims description 3
- OPIFSICVWOWJMJ-LNNRFACYSA-N 5-bromo-4-chloro-3-indolyl beta-D-glucoside Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=CNC2=CC=C(Br)C(Cl)=C12 OPIFSICVWOWJMJ-LNNRFACYSA-N 0.000 claims description 3
- 108010028144 alpha-Glucosidases Proteins 0.000 claims description 2
- 102000005936 beta-Galactosidase Human genes 0.000 claims description 2
- 108010005774 beta-Galactosidase Proteins 0.000 claims description 2
- 102000006995 beta-Glucosidase Human genes 0.000 claims description 2
- 108010047754 beta-Glucosidase Proteins 0.000 claims description 2
- SEOVTRFCIGRIMH-UHFFFAOYSA-N indole-3-acetic acid Chemical compound C1=CC=C2C(CC(=O)O)=CNC2=C1 SEOVTRFCIGRIMH-UHFFFAOYSA-N 0.000 claims description 2
- JBOPQACSHPPKEP-UHFFFAOYSA-N indoxyl acetate Natural products C1=CC=C2C(OC(=O)C)=CNC2=C1 JBOPQACSHPPKEP-UHFFFAOYSA-N 0.000 claims description 2
- 239000010409 thin film Substances 0.000 abstract description 36
- 239000010410 layer Substances 0.000 description 89
- 239000001963 growth medium Substances 0.000 description 33
- 239000010408 film Substances 0.000 description 32
- 125000006850 spacer group Chemical group 0.000 description 30
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 28
- -1 swab Substances 0.000 description 24
- 238000001514 detection method Methods 0.000 description 23
- 238000009472 formulation Methods 0.000 description 22
- 239000008199 coating composition Substances 0.000 description 21
- 229920002907 Guar gum Polymers 0.000 description 20
- 239000000665 guar gum Substances 0.000 description 20
- 235000010417 guar gum Nutrition 0.000 description 20
- 229960002154 guar gum Drugs 0.000 description 20
- 238000011534 incubation Methods 0.000 description 20
- 238000012360 testing method Methods 0.000 description 20
- HSJKGGMUJITCBW-UHFFFAOYSA-N 3-hydroxybutanal Chemical compound CC(O)CC=O HSJKGGMUJITCBW-UHFFFAOYSA-N 0.000 description 18
- 239000004820 Pressure-sensitive adhesive Substances 0.000 description 18
- 235000013305 food Nutrition 0.000 description 18
- 239000000463 material Substances 0.000 description 17
- 239000002609 medium Substances 0.000 description 16
- WQZGKKKJIJFFOK-SVZMEOIVSA-N (+)-Galactose Chemical compound OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@H]1O WQZGKKKJIJFFOK-SVZMEOIVSA-N 0.000 description 14
- 238000000576 coating method Methods 0.000 description 14
- 235000002639 sodium chloride Nutrition 0.000 description 14
- 239000000230 xanthan gum Substances 0.000 description 13
- 229920001285 xanthan gum Polymers 0.000 description 13
- 235000010493 xanthan gum Nutrition 0.000 description 13
- 229940082509 xanthan gum Drugs 0.000 description 13
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Chemical compound OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 11
- 239000006260 foam Substances 0.000 description 11
- 239000007787 solid Substances 0.000 description 11
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 10
- 239000011127 biaxially oriented polypropylene Substances 0.000 description 10
- 239000011248 coating agent Substances 0.000 description 9
- 230000000813 microbial effect Effects 0.000 description 9
- DXPPIEDUBFUSEZ-UHFFFAOYSA-N 6-methylheptyl prop-2-enoate Chemical compound CC(C)CCCCCOC(=O)C=C DXPPIEDUBFUSEZ-UHFFFAOYSA-N 0.000 description 8
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 description 8
- 239000012790 adhesive layer Substances 0.000 description 8
- 239000000017 hydrogel Substances 0.000 description 8
- 235000013372 meat Nutrition 0.000 description 8
- 239000000123 paper Substances 0.000 description 8
- 239000001967 plate count agar Substances 0.000 description 8
- PKDBCJSWQUOKDO-UHFFFAOYSA-M 2,3,5-triphenyltetrazolium chloride Chemical compound [Cl-].C1=CC=CC=C1C(N=[N+]1C=2C=CC=CC=2)=NN1C1=CC=CC=C1 PKDBCJSWQUOKDO-UHFFFAOYSA-M 0.000 description 7
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 description 7
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 7
- 229920001817 Agar Polymers 0.000 description 7
- 229910019142 PO4 Inorganic materials 0.000 description 7
- 241000589516 Pseudomonas Species 0.000 description 7
- 239000008272 agar Substances 0.000 description 7
- 229940041514 candida albicans extract Drugs 0.000 description 7
- 230000002209 hydrophobic effect Effects 0.000 description 7
- 239000002054 inoculum Substances 0.000 description 7
- 239000000178 monomer Substances 0.000 description 7
- 239000010452 phosphate Substances 0.000 description 7
- 229920006327 polystyrene foam Polymers 0.000 description 7
- 238000002360 preparation method Methods 0.000 description 7
- 239000000047 product Substances 0.000 description 7
- 239000012138 yeast extract Substances 0.000 description 7
- 241000193830 Bacillus <bacterium> Species 0.000 description 6
- 239000001888 Peptone Substances 0.000 description 6
- 108010080698 Peptones Proteins 0.000 description 6
- 239000004743 Polypropylene Substances 0.000 description 6
- 239000002390 adhesive tape Substances 0.000 description 6
- 125000001041 indolyl group Chemical group 0.000 description 6
- 239000004615 ingredient Substances 0.000 description 6
- 235000019319 peptone Nutrition 0.000 description 6
- 229920001155 polypropylene Polymers 0.000 description 6
- 241000894007 species Species 0.000 description 6
- 239000012137 tryptone Substances 0.000 description 6
- 230000000007 visual effect Effects 0.000 description 6
- 241000194032 Enterococcus faecalis Species 0.000 description 5
- 241000194034 Lactococcus lactis subsp. cremoris Species 0.000 description 5
- 241000577487 Microbacterium esteraromaticum Species 0.000 description 5
- 241000588767 Proteus vulgaris Species 0.000 description 5
- 235000014962 Streptococcus cremoris Nutrition 0.000 description 5
- 230000008901 benefit Effects 0.000 description 5
- 235000013361 beverage Nutrition 0.000 description 5
- 229920006378 biaxially oriented polypropylene Polymers 0.000 description 5
- 229940032049 enterococcus faecalis Drugs 0.000 description 5
- 239000002655 kraft paper Substances 0.000 description 5
- RZXMPPFPUUCRFN-UHFFFAOYSA-N p-toluidine Chemical class CC1=CC=C(N)C=C1 RZXMPPFPUUCRFN-UHFFFAOYSA-N 0.000 description 5
- 239000013047 polymeric layer Substances 0.000 description 5
- 230000008569 process Effects 0.000 description 5
- 229940007042 proteus vulgaris Drugs 0.000 description 5
- 238000003756 stirring Methods 0.000 description 5
- LVLOFXJWZQNNRX-UHFFFAOYSA-N 4-methylaniline;phosphoric acid Chemical compound OP(O)(O)=O.CC1=CC=C(N)C=C1 LVLOFXJWZQNNRX-UHFFFAOYSA-N 0.000 description 4
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 4
- LCTONWCANYUPML-UHFFFAOYSA-N Pyruvic acid Chemical compound CC(=O)C(O)=O LCTONWCANYUPML-UHFFFAOYSA-N 0.000 description 4
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 4
- 239000006172 buffering agent Substances 0.000 description 4
- 229910052943 magnesium sulfate Inorganic materials 0.000 description 4
- 235000019341 magnesium sulphate Nutrition 0.000 description 4
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 4
- 235000018102 proteins Nutrition 0.000 description 4
- 102000004169 proteins and genes Human genes 0.000 description 4
- 108090000623 proteins and genes Proteins 0.000 description 4
- 238000003860 storage Methods 0.000 description 4
- LWIHDJKSTIGBAC-UHFFFAOYSA-K tripotassium phosphate Chemical compound [K+].[K+].[K+].[O-]P([O-])([O-])=O LWIHDJKSTIGBAC-UHFFFAOYSA-K 0.000 description 4
- QEIFSLUFHRCVQL-UHFFFAOYSA-N (5-bromo-4-chloro-1h-indol-3-yl) hydrogen phosphate;(4-methylphenyl)azanium Chemical compound CC1=CC=C(N)C=C1.C1=C(Br)C(Cl)=C2C(OP(O)(=O)O)=CNC2=C1 QEIFSLUFHRCVQL-UHFFFAOYSA-N 0.000 description 3
- KWTQSFXGGICVPE-UHFFFAOYSA-N 2-amino-5-(diaminomethylideneamino)pentanoic acid;hydron;chloride Chemical compound Cl.OC(=O)C(N)CCCN=C(N)N KWTQSFXGGICVPE-UHFFFAOYSA-N 0.000 description 3
- HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical compound NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 description 3
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 description 3
- SRBFZHDQGSBBOR-IOVATXLUSA-N D-xylopyranose Chemical compound O[C@@H]1COC(O)[C@H](O)[C@H]1O SRBFZHDQGSBBOR-IOVATXLUSA-N 0.000 description 3
- 241000588724 Escherichia coli Species 0.000 description 3
- 241000579722 Kocuria Species 0.000 description 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- 239000004698 Polyethylene Substances 0.000 description 3
- 239000004793 Polystyrene Substances 0.000 description 3
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 3
- 241000193985 Streptococcus agalactiae Species 0.000 description 3
- 125000005250 alkyl acrylate group Chemical group 0.000 description 3
- 239000001110 calcium chloride Substances 0.000 description 3
- 229910001628 calcium chloride Inorganic materials 0.000 description 3
- 235000011148 calcium chloride Nutrition 0.000 description 3
- 239000003086 colorant Substances 0.000 description 3
- 238000010790 dilution Methods 0.000 description 3
- 239000012895 dilution Substances 0.000 description 3
- ZPWVASYFFYYZEW-UHFFFAOYSA-L dipotassium hydrogen phosphate Chemical compound [K+].[K+].OP([O-])([O-])=O ZPWVASYFFYYZEW-UHFFFAOYSA-L 0.000 description 3
- 235000021186 dishes Nutrition 0.000 description 3
- 230000007613 environmental effect Effects 0.000 description 3
- 239000000499 gel Substances 0.000 description 3
- 230000036571 hydration Effects 0.000 description 3
- 238000006703 hydration reaction Methods 0.000 description 3
- 239000012982 microporous membrane Substances 0.000 description 3
- 238000002156 mixing Methods 0.000 description 3
- 235000019796 monopotassium phosphate Nutrition 0.000 description 3
- 229910052757 nitrogen Inorganic materials 0.000 description 3
- 230000035699 permeability Effects 0.000 description 3
- 229920000573 polyethylene Polymers 0.000 description 3
- 229920002223 polystyrene Polymers 0.000 description 3
- NLKNQRATVPKPDG-UHFFFAOYSA-M potassium iodide Chemical compound [K+].[I-] NLKNQRATVPKPDG-UHFFFAOYSA-M 0.000 description 3
- 230000002829 reductive effect Effects 0.000 description 3
- 159000000000 sodium salts Chemical class 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 239000004552 water soluble powder Substances 0.000 description 3
- NWONKYPBYAMBJT-UHFFFAOYSA-L zinc sulfate Chemical compound [Zn+2].[O-]S([O-])(=O)=O NWONKYPBYAMBJT-UHFFFAOYSA-L 0.000 description 3
- 229910000368 zinc sulfate Inorganic materials 0.000 description 3
- 229960001763 zinc sulfate Drugs 0.000 description 3
- BCHIXGBGRHLSBE-UHFFFAOYSA-N (4-methyl-2-oxochromen-7-yl) dihydrogen phosphate Chemical compound C1=C(OP(O)(O)=O)C=CC2=C1OC(=O)C=C2C BCHIXGBGRHLSBE-UHFFFAOYSA-N 0.000 description 2
- JWYVGKFDLWWQJX-UHFFFAOYSA-N 1-ethenylazepan-2-one Chemical compound C=CN1CCCCCC1=O JWYVGKFDLWWQJX-UHFFFAOYSA-N 0.000 description 2
- JTNGEYANGCBZLK-UHFFFAOYSA-N 1h-indol-3-yl dihydrogen phosphate Chemical compound C1=CC=C2C(OP(O)(=O)O)=CNC2=C1 JTNGEYANGCBZLK-UHFFFAOYSA-N 0.000 description 2
- HSHNITRMYYLLCV-UHFFFAOYSA-N 4-methylumbelliferone Chemical compound C1=C(O)C=CC2=C1OC(=O)C=C2C HSHNITRMYYLLCV-UHFFFAOYSA-N 0.000 description 2
- HXVZGASCDAGAPS-UHFFFAOYSA-N 4-methylumbelliferyl acetate Chemical compound CC1=CC(=O)OC2=CC(OC(=O)C)=CC=C21 HXVZGASCDAGAPS-UHFFFAOYSA-N 0.000 description 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 241000194108 Bacillus licheniformis Species 0.000 description 2
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 description 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 2
- 229920000161 Locust bean gum Polymers 0.000 description 2
- TWRXJAOTZQYOKJ-UHFFFAOYSA-L Magnesium chloride Chemical compound [Mg+2].[Cl-].[Cl-] TWRXJAOTZQYOKJ-UHFFFAOYSA-L 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 description 2
- AFBPFSWMIHJQDM-UHFFFAOYSA-N N-methyl-N-phenylamine Natural products CNC1=CC=CC=C1 AFBPFSWMIHJQDM-UHFFFAOYSA-N 0.000 description 2
- 241000589776 Pseudomonas putida Species 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 241000191967 Staphylococcus aureus Species 0.000 description 2
- KVIYXIWBXOQZDN-UHFFFAOYSA-N [3-(phenylcarbamoyl)naphthalen-2-yl] dihydrogen phosphate Chemical compound OP(O)(=O)OC1=CC2=CC=CC=C2C=C1C(=O)NC1=CC=CC=C1 KVIYXIWBXOQZDN-UHFFFAOYSA-N 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 150000003926 acrylamides Chemical class 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 2
- SRBFZHDQGSBBOR-UHFFFAOYSA-N beta-D-Pyranose-Lyxose Natural products OC1COC(O)C(O)C1O SRBFZHDQGSBBOR-UHFFFAOYSA-N 0.000 description 2
- 239000000872 buffer Substances 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 230000001332 colony forming effect Effects 0.000 description 2
- 238000011109 contamination Methods 0.000 description 2
- 229920001577 copolymer Polymers 0.000 description 2
- 230000008878 coupling Effects 0.000 description 2
- 238000010168 coupling process Methods 0.000 description 2
- 238000005859 coupling reaction Methods 0.000 description 2
- 239000008121 dextrose Substances 0.000 description 2
- 239000003085 diluting agent Substances 0.000 description 2
- 229910001882 dioxygen Inorganic materials 0.000 description 2
- 229910000396 dipotassium phosphate Inorganic materials 0.000 description 2
- 150000008271 glucosaminides Chemical class 0.000 description 2
- 229930182480 glucuronide Natural products 0.000 description 2
- 239000008240 homogeneous mixture Substances 0.000 description 2
- 230000007062 hydrolysis Effects 0.000 description 2
- 238000006460 hydrolysis reaction Methods 0.000 description 2
- 238000005286 illumination Methods 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- 238000002955 isolation Methods 0.000 description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
- 230000000670 limiting effect Effects 0.000 description 2
- 235000010420 locust bean gum Nutrition 0.000 description 2
- 239000000711 locust bean gum Substances 0.000 description 2
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 description 2
- 235000013336 milk Nutrition 0.000 description 2
- 239000008267 milk Substances 0.000 description 2
- 210000004080 milk Anatomy 0.000 description 2
- 229910000402 monopotassium phosphate Inorganic materials 0.000 description 2
- 239000007800 oxidant agent Substances 0.000 description 2
- 229910052760 oxygen Inorganic materials 0.000 description 2
- 239000001301 oxygen Substances 0.000 description 2
- 230000002093 peripheral effect Effects 0.000 description 2
- GNSKLFRGEWLPPA-UHFFFAOYSA-M potassium dihydrogen phosphate Chemical compound [K+].OP(O)([O-])=O GNSKLFRGEWLPPA-UHFFFAOYSA-M 0.000 description 2
- 229910000160 potassium phosphate Inorganic materials 0.000 description 2
- 229940093916 potassium phosphate Drugs 0.000 description 2
- 235000011009 potassium phosphates Nutrition 0.000 description 2
- 229940107700 pyruvic acid Drugs 0.000 description 2
- 238000007789 sealing Methods 0.000 description 2
- 229910000029 sodium carbonate Inorganic materials 0.000 description 2
- 239000008223 sterile water Substances 0.000 description 2
- NKQFKJYKCVDLPT-KHPPLWFESA-N (4-methyl-2-oxochromen-7-yl) (z)-octadec-9-enoate Chemical compound CC1=CC(=O)OC2=CC(OC(=O)CCCCCCC\C=C/CCCCCCCC)=CC=C21 NKQFKJYKCVDLPT-KHPPLWFESA-N 0.000 description 1
- QOIJAZYHGUNKLA-UHFFFAOYSA-N (4-methyl-2-oxochromen-7-yl) octadecanoate Chemical compound CC1=CC(=O)OC2=CC(OC(=O)CCCCCCCCCCCCCCCCC)=CC=C21 QOIJAZYHGUNKLA-UHFFFAOYSA-N 0.000 description 1
- IOKUIFTUULBXMB-UHFFFAOYSA-N (4-methyl-2-oxochromen-7-yl) propanoate Chemical compound CC1=CC(=O)OC2=CC(OC(=O)CC)=CC=C21 IOKUIFTUULBXMB-UHFFFAOYSA-N 0.000 description 1
- CJUUXVFWKYRHAR-UHFFFAOYSA-M 1-Naphthaleneacetic acid sodium salt Chemical compound [Na+].C1=CC=C2C(CC(=O)[O-])=CC=CC2=C1 CJUUXVFWKYRHAR-UHFFFAOYSA-M 0.000 description 1
- DVFSEXUMYANGAN-UHFFFAOYSA-N 1h-indol-3-yl dihydrogen phosphate;4-methylaniline Chemical compound CC1=CC=C(N)C=C1.C1=CC=C2C(OP(O)(=O)O)=CNC2=C1 DVFSEXUMYANGAN-UHFFFAOYSA-N 0.000 description 1
- GOXQRTZXKQZDDN-UHFFFAOYSA-N 2-Ethylhexyl acrylate Chemical compound CCCCC(CC)COC(=O)C=C GOXQRTZXKQZDDN-UHFFFAOYSA-N 0.000 description 1
- SGPKEYSZPHMVNI-UHFFFAOYSA-N 2-bromo-1-(2-hydroxyphenyl)ethanone Chemical compound OC1=CC=CC=C1C(=O)CBr SGPKEYSZPHMVNI-UHFFFAOYSA-N 0.000 description 1
- ZVYGIPWYVVJFRW-UHFFFAOYSA-N 3-methylbutyl prop-2-enoate Chemical compound CC(C)CCOC(=O)C=C ZVYGIPWYVVJFRW-UHFFFAOYSA-N 0.000 description 1
- WKPUJZVCZXWKCK-UHFFFAOYSA-N 4-methylumbelliferyl butyate Chemical compound CC1=CC(=O)OC2=CC(OC(=O)CCC)=CC=C21 WKPUJZVCZXWKCK-UHFFFAOYSA-N 0.000 description 1
- 241000251468 Actinopterygii Species 0.000 description 1
- 241000588813 Alcaligenes faecalis Species 0.000 description 1
- 241000193755 Bacillus cereus Species 0.000 description 1
- FERIUCNNQQJTOY-UHFFFAOYSA-M Butyrate Chemical compound CCCC([O-])=O FERIUCNNQQJTOY-UHFFFAOYSA-M 0.000 description 1
- FERIUCNNQQJTOY-UHFFFAOYSA-N Butyric acid Natural products CCCC(O)=O FERIUCNNQQJTOY-UHFFFAOYSA-N 0.000 description 1
- XGBYQUDXMVJUJY-FAOVPRGRSA-N C(CCC(=O)O)(=O)O.C(C(=O)C)(=O)O.O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO Chemical compound C(CCC(=O)O)(=O)O.C(C(=O)C)(=O)O.O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO XGBYQUDXMVJUJY-FAOVPRGRSA-N 0.000 description 1
- XUSMHPKPDSWCJD-UHFFFAOYSA-L C1(=CC=CC2=CC=CC=C12)O.[Na+].[Na+].C1(=CC=CC2=CC=CC=C12)OP(=O)([O-])[O-].C(C)(=O)OC1=CC2=CC=C(C=C2C=C1)Br.[Na+] Chemical compound C1(=CC=CC2=CC=CC=C12)O.[Na+].[Na+].C1(=CC=CC2=CC=CC=C12)OP(=O)([O-])[O-].C(C)(=O)OC1=CC2=CC=C(C=C2C=C1)Br.[Na+] XUSMHPKPDSWCJD-UHFFFAOYSA-L 0.000 description 1
- HUBLCBRLWGGVFJ-UHFFFAOYSA-L C1(=CC=CC2=CC=CC=C12)O.[Na+].[Na+].C1=C(C=CC2=CC=CC=C12)OP(=O)([O-])[O-] Chemical compound C1(=CC=CC2=CC=CC=C12)O.[Na+].[Na+].C1=C(C=CC2=CC=CC=C12)OP(=O)([O-])[O-] HUBLCBRLWGGVFJ-UHFFFAOYSA-L 0.000 description 1
- RMRKOWJBHMLWBN-UHFFFAOYSA-K C1(=CC=CC2=CC=CC=C12)OC(CCCCCCC)=O.[Na+].C1(=CC=CC2=CC=CC=C12)OP(=O)([O-])[O-].C1=C(C=CC2=CC=CC=C12)OC(CCC)=O.[Na+].C1=C(C=CC2=CC=CC=C12)OP(=O)([O-])O.C1(=CC=CC2=CC=CC=C12)OC(CCC)=O.[Na+].C1=C(C=CC2=CC=CC=C12)OP(=O)(O)O Chemical compound C1(=CC=CC2=CC=CC=C12)OC(CCCCCCC)=O.[Na+].C1(=CC=CC2=CC=CC=C12)OP(=O)([O-])[O-].C1=C(C=CC2=CC=CC=C12)OC(CCC)=O.[Na+].C1=C(C=CC2=CC=CC=C12)OP(=O)([O-])O.C1(=CC=CC2=CC=CC=C12)OC(CCC)=O.[Na+].C1=C(C=CC2=CC=CC=C12)OP(=O)(O)O RMRKOWJBHMLWBN-UHFFFAOYSA-K 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 229920002134 Carboxymethyl cellulose Polymers 0.000 description 1
- 241001660259 Cereus <cactus> Species 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- 241000588923 Citrobacter Species 0.000 description 1
- 150000008491 D-fucopyranosides Chemical class 0.000 description 1
- QXNVGIXVLWOKEQ-UHFFFAOYSA-N Disodium Chemical class [Na][Na] QXNVGIXVLWOKEQ-UHFFFAOYSA-N 0.000 description 1
- 241000588914 Enterobacter Species 0.000 description 1
- 241000194033 Enterococcus Species 0.000 description 1
- 241000588722 Escherichia Species 0.000 description 1
- JIGUQPWFLRLWPJ-UHFFFAOYSA-N Ethyl acrylate Chemical compound CCOC(=O)C=C JIGUQPWFLRLWPJ-UHFFFAOYSA-N 0.000 description 1
- IAJILQKETJEXLJ-UHFFFAOYSA-N Galacturonsaeure Natural products O=CC(O)C(O)C(O)C(O)C(O)=O IAJILQKETJEXLJ-UHFFFAOYSA-N 0.000 description 1
- 241000606790 Haemophilus Species 0.000 description 1
- 239000004354 Hydroxyethyl cellulose Substances 0.000 description 1
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 235000000177 Indigofera tinctoria Nutrition 0.000 description 1
- 229910021578 Iron(III) chloride Inorganic materials 0.000 description 1
- 239000007993 MOPS buffer Substances 0.000 description 1
- 229910021380 Manganese Chloride Inorganic materials 0.000 description 1
- GLFNIEUTAYBVOC-UHFFFAOYSA-L Manganese chloride Chemical compound Cl[Mn]Cl GLFNIEUTAYBVOC-UHFFFAOYSA-L 0.000 description 1
- 241001467578 Microbacterium Species 0.000 description 1
- 102000015636 Oligopeptides Human genes 0.000 description 1
- 108010038807 Oligopeptides Proteins 0.000 description 1
- 108091005804 Peptidases Proteins 0.000 description 1
- 102000035195 Peptidases Human genes 0.000 description 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- 108010009736 Protein Hydrolysates Proteins 0.000 description 1
- 241000588769 Proteus <enterobacteria> Species 0.000 description 1
- 241000191940 Staphylococcus Species 0.000 description 1
- 241000194017 Streptococcus Species 0.000 description 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 1
- ATJFFYVFTNAWJD-UHFFFAOYSA-N Tin Chemical compound [Sn] ATJFFYVFTNAWJD-UHFFFAOYSA-N 0.000 description 1
- 241000607598 Vibrio Species 0.000 description 1
- 241000607734 Yersinia <bacteria> Species 0.000 description 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- YHLRJFWBPIUKCC-UHFFFAOYSA-M [N+](=O)([O-])C1=C(C=CC=C1)C(C(=O)[O-])CC.[K+] Chemical compound [N+](=O)([O-])C1=C(C=CC=C1)C(C(=O)[O-])CC.[K+] YHLRJFWBPIUKCC-UHFFFAOYSA-M 0.000 description 1
- YJWCFAWDBUFKSQ-UHFFFAOYSA-L [N+](=O)([O-])C1=CC=C(C=C1)C(C(=O)[O-])CCCCCC.[Na+].[Na+].[N+](=O)([O-])C1=CC=C(C=C1)C(C(=O)[O-])CCCCCC Chemical compound [N+](=O)([O-])C1=CC=C(C=C1)C(C(=O)[O-])CCCCCC.[Na+].[Na+].[N+](=O)([O-])C1=CC=C(C=C1)C(C(=O)[O-])CCCCCC YJWCFAWDBUFKSQ-UHFFFAOYSA-L 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 238000005273 aeration Methods 0.000 description 1
- 230000009603 aerobic growth Effects 0.000 description 1
- 230000004103 aerobic respiration Effects 0.000 description 1
- 238000013019 agitation Methods 0.000 description 1
- 239000003570 air Substances 0.000 description 1
- 229940005347 alcaligenes faecalis Drugs 0.000 description 1
- IAJILQKETJEXLJ-QTBDOELSSA-N aldehydo-D-glucuronic acid Chemical compound O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)C(O)=O IAJILQKETJEXLJ-QTBDOELSSA-N 0.000 description 1
- 235000010443 alginic acid Nutrition 0.000 description 1
- 229920000615 alginic acid Polymers 0.000 description 1
- SHZGCJCMOBCMKK-PHYPRBDBSA-N alpha-D-fucose Chemical compound C[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O SHZGCJCMOBCMKK-PHYPRBDBSA-N 0.000 description 1
- 229940024606 amino acid Drugs 0.000 description 1
- 235000001014 amino acid Nutrition 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- FRHBOQMZUOWXQL-UHFFFAOYSA-L ammonium ferric citrate Chemical compound [NH4+].[Fe+3].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O FRHBOQMZUOWXQL-UHFFFAOYSA-L 0.000 description 1
- 150000003863 ammonium salts Chemical class 0.000 description 1
- 239000012062 aqueous buffer Substances 0.000 description 1
- PYMYPHUHKUWMLA-UHFFFAOYSA-N arabinose Natural products OCC(O)C(O)C(O)C=O PYMYPHUHKUWMLA-UHFFFAOYSA-N 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 description 1
- 239000004327 boric acid Substances 0.000 description 1
- 235000010338 boric acid Nutrition 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 235000008429 bread Nutrition 0.000 description 1
- CQEYYJKEWSMYFG-UHFFFAOYSA-N butyl acrylate Chemical compound CCCCOC(=O)C=C CQEYYJKEWSMYFG-UHFFFAOYSA-N 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 229960002713 calcium chloride Drugs 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 235000014633 carbohydrates Nutrition 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 239000001768 carboxy methyl cellulose Substances 0.000 description 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 description 1
- 239000011111 cardboard Substances 0.000 description 1
- 108010079058 casein hydrolysate Proteins 0.000 description 1
- 230000033077 cellular process Effects 0.000 description 1
- 235000013339 cereals Nutrition 0.000 description 1
- 235000013351 cheese Nutrition 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000003593 chromogenic compound Substances 0.000 description 1
- 229910017052 cobalt Inorganic materials 0.000 description 1
- 239000010941 cobalt Substances 0.000 description 1
- GUTLYIVDDKVIGB-UHFFFAOYSA-N cobalt atom Chemical compound [Co] GUTLYIVDDKVIGB-UHFFFAOYSA-N 0.000 description 1
- 230000005757 colony formation Effects 0.000 description 1
- 235000013409 condiments Nutrition 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 229910000365 copper sulfate Inorganic materials 0.000 description 1
- ARUVKPQLZAKDPS-UHFFFAOYSA-L copper(II) sulfate Chemical compound [Cu+2].[O-][S+2]([O-])([O-])[O-] ARUVKPQLZAKDPS-UHFFFAOYSA-L 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 235000015142 cultured sour cream Nutrition 0.000 description 1
- PAFZNILMFXTMIY-UHFFFAOYSA-N cyclohexylamine Chemical class NC1CCCCC1 PAFZNILMFXTMIY-UHFFFAOYSA-N 0.000 description 1
- 239000008367 deionised water Substances 0.000 description 1
- 229910021641 deionized water Inorganic materials 0.000 description 1
- 230000008021 deposition Effects 0.000 description 1
- 235000011850 desserts Nutrition 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- 238000007865 diluting Methods 0.000 description 1
- 235000019797 dipotassium phosphate Nutrition 0.000 description 1
- BNIILDVGGAEEIG-UHFFFAOYSA-L disodium hydrogen phosphate Chemical compound [Na+].[Na+].OP([O-])([O-])=O BNIILDVGGAEEIG-UHFFFAOYSA-L 0.000 description 1
- OAZUOCJOEUNDEK-UHFFFAOYSA-L disodium;(5-bromo-4-chloro-1h-indol-3-yl) phosphate Chemical compound [Na+].[Na+].C1=C(Br)C(Cl)=C2C(OP([O-])(=O)[O-])=CNC2=C1 OAZUOCJOEUNDEK-UHFFFAOYSA-L 0.000 description 1
- WCSKWBKPKXJWEG-UHFFFAOYSA-L disodium;1h-indol-3-yl phosphate Chemical compound [Na+].[Na+].C1=CC=C2C(OP([O-])(=O)[O-])=CNC2=C1 WCSKWBKPKXJWEG-UHFFFAOYSA-L 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 235000013601 eggs Nutrition 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- 230000002255 enzymatic effect Effects 0.000 description 1
- CCIVGXIOQKPBKL-UHFFFAOYSA-M ethanesulfonate Chemical compound CCS([O-])(=O)=O CCIVGXIOQKPBKL-UHFFFAOYSA-M 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 239000003925 fat Substances 0.000 description 1
- 235000019197 fats Nutrition 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- 238000000855 fermentation Methods 0.000 description 1
- 230000004151 fermentation Effects 0.000 description 1
- 229960004642 ferric ammonium citrate Drugs 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 235000019688 fish Nutrition 0.000 description 1
- 235000013312 flour Nutrition 0.000 description 1
- 150000008272 galactosaminides Chemical class 0.000 description 1
- 150000008195 galaktosides Chemical class 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 229940097043 glucuronic acid Drugs 0.000 description 1
- 150000008134 glucuronides Chemical class 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 235000011868 grain product Nutrition 0.000 description 1
- WHWDWIHXSPCOKZ-UHFFFAOYSA-N hexahydrofarnesyl acetone Natural products CC(C)CCCC(C)CCCC(C)CCCC(C)=O WHWDWIHXSPCOKZ-UHFFFAOYSA-N 0.000 description 1
- 238000000265 homogenisation Methods 0.000 description 1
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 description 1
- 238000010191 image analysis Methods 0.000 description 1
- 229940097275 indigo Drugs 0.000 description 1
- COHYTHOBJLSHDF-UHFFFAOYSA-N indigo powder Natural products N1C2=CC=CC=C2C(=O)C1=C1C(=O)C2=CC=CC=C2N1 COHYTHOBJLSHDF-UHFFFAOYSA-N 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 238000011081 inoculation Methods 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- 239000004313 iron ammonium citrate Substances 0.000 description 1
- 235000000011 iron ammonium citrate Nutrition 0.000 description 1
- RBTARNINKXHZNM-UHFFFAOYSA-K iron trichloride Chemical compound Cl[Fe](Cl)Cl RBTARNINKXHZNM-UHFFFAOYSA-K 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 230000031700 light absorption Effects 0.000 description 1
- 229910001629 magnesium chloride Inorganic materials 0.000 description 1
- 229960003390 magnesium sulfate Drugs 0.000 description 1
- 239000011565 manganese chloride Substances 0.000 description 1
- 235000002867 manganese chloride Nutrition 0.000 description 1
- 229940099607 manganese chloride Drugs 0.000 description 1
- 229940099596 manganese sulfate Drugs 0.000 description 1
- 239000011702 manganese sulphate Substances 0.000 description 1
- 235000007079 manganese sulphate Nutrition 0.000 description 1
- WPBNNNQJVZRUHP-UHFFFAOYSA-L manganese(2+);methyl n-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate;n-[2-(sulfidocarbothioylamino)ethyl]carbamodithioate Chemical compound [Mn+2].[S-]C(=S)NCCNC([S-])=S.COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC WPBNNNQJVZRUHP-UHFFFAOYSA-L 0.000 description 1
- SQQMAOCOWKFBNP-UHFFFAOYSA-L manganese(II) sulfate Chemical compound [Mn+2].[O-]S([O-])(=O)=O SQQMAOCOWKFBNP-UHFFFAOYSA-L 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000005374 membrane filtration Methods 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- FQPSGWSUVKBHSU-UHFFFAOYSA-N methacrylamide Chemical compound CC(=C)C(N)=O FQPSGWSUVKBHSU-UHFFFAOYSA-N 0.000 description 1
- 244000000010 microbial pathogen Species 0.000 description 1
- 230000002906 microbiologic effect Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 229940111688 monobasic potassium phosphate Drugs 0.000 description 1
- 229910000403 monosodium phosphate Inorganic materials 0.000 description 1
- 235000019799 monosodium phosphate Nutrition 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 235000019198 oils Nutrition 0.000 description 1
- 229920001542 oligosaccharide Polymers 0.000 description 1
- 150000002482 oligosaccharides Chemical class 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 235000016046 other dairy product Nutrition 0.000 description 1
- 239000011087 paperboard Substances 0.000 description 1
- 239000011236 particulate material Substances 0.000 description 1
- 238000005192 partition Methods 0.000 description 1
- 235000015927 pasta Nutrition 0.000 description 1
- PNJWIWWMYCMZRO-UHFFFAOYSA-N pent‐4‐en‐2‐one Natural products CC(=O)CC=C PNJWIWWMYCMZRO-UHFFFAOYSA-N 0.000 description 1
- 150000003013 phosphoric acid derivatives Chemical class 0.000 description 1
- PJNZPQUBCPKICU-UHFFFAOYSA-N phosphoric acid;potassium Chemical compound [K].OP(O)(O)=O PJNZPQUBCPKICU-UHFFFAOYSA-N 0.000 description 1
- 229910052698 phosphorus Inorganic materials 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- 239000002798 polar solvent Substances 0.000 description 1
- 229920002401 polyacrylamide Polymers 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 229920006267 polyester film Polymers 0.000 description 1
- 239000005020 polyethylene terephthalate Substances 0.000 description 1
- 229920000139 polyethylene terephthalate Polymers 0.000 description 1
- 229920000098 polyolefin Polymers 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 244000144977 poultry Species 0.000 description 1
- 235000013594 poultry meat Nutrition 0.000 description 1
- 235000013324 preserved food Nutrition 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000000644 propagated effect Effects 0.000 description 1
- AKABMDSULDRXEO-UHFFFAOYSA-N propan-2-yl 2-(4-chlorophenoxy)-2-methylpropanoate Chemical compound CC(C)OC(=O)C(C)(C)OC1=CC=C(Cl)C=C1 AKABMDSULDRXEO-UHFFFAOYSA-N 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 239000003531 protein hydrolysate Substances 0.000 description 1
- 239000008213 purified water Substances 0.000 description 1
- 238000010791 quenching Methods 0.000 description 1
- 230000000171 quenching effect Effects 0.000 description 1
- 238000005057 refrigeration Methods 0.000 description 1
- 230000010076 replication Effects 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 235000015067 sauces Nutrition 0.000 description 1
- 235000014102 seafood Nutrition 0.000 description 1
- 239000012056 semi-solid material Substances 0.000 description 1
- 239000002356 single layer Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical compound [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 description 1
- 239000011684 sodium molybdate Substances 0.000 description 1
- 235000015393 sodium molybdate Nutrition 0.000 description 1
- TVXXNOYZHKPKGW-UHFFFAOYSA-N sodium molybdate (anhydrous) Chemical compound [Na+].[Na+].[O-][Mo]([O-])(=O)=O TVXXNOYZHKPKGW-UHFFFAOYSA-N 0.000 description 1
- MWEMXEWFLIDTSJ-UHFFFAOYSA-M sodium;3-morpholin-4-ylpropane-1-sulfonate Chemical compound [Na+].[O-]S(=O)(=O)CCCN1CCOCC1 MWEMXEWFLIDTSJ-UHFFFAOYSA-M 0.000 description 1
- DELHRHCJGSTQNU-UHFFFAOYSA-M sodium;bis(4-nitrophenyl) phosphate Chemical compound [Na+].C1=CC([N+](=O)[O-])=CC=C1OP([O-])(=O)OC1=CC=C([N+]([O-])=O)C=C1 DELHRHCJGSTQNU-UHFFFAOYSA-M 0.000 description 1
- 239000002689 soil Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 235000014347 soups Nutrition 0.000 description 1
- 235000013599 spices Nutrition 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 235000000346 sugar Nutrition 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 239000011593 sulfur Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 229920002994 synthetic fiber Polymers 0.000 description 1
- 238000010345 tape casting Methods 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- HTMKLCRJVFFVDW-UHFFFAOYSA-J tetrasodium;[4-[3-oxo-1-(4-phosphonatooxyphenyl)-2-benzofuran-1-yl]phenyl] phosphate Chemical compound [Na+].[Na+].[Na+].[Na+].C1=CC(OP([O-])(=O)[O-])=CC=C1C1(C=2C=CC(OP([O-])([O-])=O)=CC=2)C2=CC=CC=C2C(=O)O1 HTMKLCRJVFFVDW-UHFFFAOYSA-J 0.000 description 1
- 229910052718 tin Inorganic materials 0.000 description 1
- 239000011135 tin Substances 0.000 description 1
- 239000001974 tryptic soy broth Substances 0.000 description 1
- 239000006150 trypticase soy agar Substances 0.000 description 1
- 108010050327 trypticase-soy broth Proteins 0.000 description 1
- 241001148471 unidentified anaerobic bacterium Species 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 238000011179 visual inspection Methods 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
- 235000013618 yogurt Nutrition 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
- C12M41/36—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of biomass, e.g. colony counters or by turbidity measurements
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/42—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving phosphatase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/44—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving esterase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2334/00—O-linked chromogens for determinations of hydrolase enzymes, e.g. glycosidases, phosphatases, esterases
- C12Q2334/50—Indoles
- C12Q2334/52—5-Bromo-4-chloro-3-indolyl, i.e. BCI
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Toxicology (AREA)
- Biomedical Technology (AREA)
- Sustainable Development (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201461949631P | 2014-03-07 | 2014-03-07 | |
US61/949,631 | 2014-03-07 | ||
PCT/US2015/018844 WO2015134686A1 (en) | 2014-03-07 | 2015-03-05 | Article and method for detecting aerobic bacteria |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2941689A1 true CA2941689A1 (en) | 2015-09-11 |
Family
ID=52684724
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2941689A Abandoned CA2941689A1 (en) | 2014-03-07 | 2015-03-05 | Article and method for detecting aerobic bacteria |
Country Status (10)
Country | Link |
---|---|
US (2) | US20170073629A1 (ko) |
EP (2) | EP3114209B1 (ko) |
JP (2) | JP2017506916A (ko) |
KR (1) | KR102436447B1 (ko) |
CN (2) | CN106103689A (ko) |
AU (1) | AU2015227127B2 (ko) |
BR (1) | BR112016020570B1 (ko) |
CA (1) | CA2941689A1 (ko) |
MX (1) | MX2016011466A (ko) |
WO (1) | WO2015134686A1 (ko) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4584019B2 (ja) | 2005-05-10 | 2010-11-17 | 三菱電機ビルテクノサービス株式会社 | エレベータの制御装置 |
CN107002008B (zh) | 2014-11-25 | 2021-04-02 | 3M创新有限公司 | 用于增殖或储存微生物的装置和套件及其制备和使用方法 |
JP2017139981A (ja) * | 2016-02-09 | 2017-08-17 | Jnc株式会社 | 微生物検出用培地 |
EP3562930B1 (en) * | 2016-12-28 | 2021-09-01 | 3M Innovative Properties Company | Microbial detection devices including adhesive masked nutrients and methods of using the same |
JP7385791B2 (ja) * | 2016-12-28 | 2023-11-24 | ネオゲン フード セイフティ ユーエス ホルドコ コーポレイション | 微生物検出デバイス、及びその使用方法 |
WO2019116259A1 (en) | 2017-12-13 | 2019-06-20 | 3M Innovative Properties Company | Water-reconstitutable culture medium resistant to liquefaction by microorganisms |
WO2023112035A1 (en) * | 2021-12-16 | 2023-06-22 | Do-Bio Ltd | Indicator device and system and uses thereof for detecting food spoilage |
WO2024111865A1 (ko) * | 2022-11-21 | 2024-05-30 | 주식회사 리플라 | 플라스틱 분해 활성을 갖는 미생물 판별 방법 |
Family Cites Families (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4565783A (en) | 1981-01-27 | 1986-01-21 | Minnesota Mining And Manufacturing Company | Dry culture media |
US5089413A (en) | 1989-05-19 | 1992-02-18 | Minnesota Mining And Manufacturing Company | Method and apparatus for culturing with microbiological dry culture medium |
GB9002003D0 (en) | 1990-01-29 | 1990-03-28 | Ici Plc | Stabilized cultures of microorganisms |
US6058209A (en) | 1991-09-27 | 2000-05-02 | E. I. Du Pont De Nemours And Company | Method for resolving redundant identifications of an object |
US5448652A (en) | 1991-09-27 | 1995-09-05 | E. I. Du Pont De Nemours And Company | Adaptive display system |
US5232838A (en) * | 1991-12-09 | 1993-08-03 | Minnesota Mining And Manufacturing Company | Culture media device and method of use |
US5364766A (en) | 1993-05-14 | 1994-11-15 | Minnesota Mining And Manufacturing Company | Culture medium for rapid count of coliform bacteria |
FR2708286B1 (fr) | 1993-07-28 | 1995-10-20 | Rambach Alain | Procédé d'identification de microorganismes avec au moins deux chromogènes. |
US5443963A (en) | 1994-01-31 | 1995-08-22 | Minnesota Mining And Manufacturing Company | Method for detecting staphylococci |
US5464755A (en) | 1994-04-29 | 1995-11-07 | Biolog, Inc. | Microbiological medium and method of assay |
US5601998A (en) | 1994-08-18 | 1997-02-11 | Minnesota Mining & Mfg | Culture medium and device for detection and enumeration of enterobacteriaceae |
US5681712A (en) * | 1995-06-02 | 1997-10-28 | Minnesota Mining And Manufacturing Company | Surface colony counting device and method of use |
US6387650B1 (en) * | 1995-06-07 | 2002-05-14 | Biocontrol Systems, Inc. | Method and composition for detecting bacterial contamination in food products |
US6381353B1 (en) | 1996-08-30 | 2002-04-30 | Marvin Weiss | System for counting colonies of micro-organisms in petri dishes and other culture media |
US5854011A (en) | 1996-12-19 | 1998-12-29 | Idexx Laboratories Incorporated | Method and components for the detection of yeasts and/or molds in a sample |
US5888760A (en) | 1997-04-10 | 1999-03-30 | Dade Microscan Inc. | Universal test systems and methods of use thereof for identifying multiple families of microorganisms |
US5958675A (en) * | 1997-04-18 | 1999-09-28 | 3M Innovative Properties Company | Method for detecting bacteria using bacteriophage, contrast-coloring dye and precipitable dye |
US6271022B1 (en) | 1999-03-12 | 2001-08-07 | Biolog, Inc. | Device for incubating and monitoring multiwell assays |
US20020086278A1 (en) | 1999-09-28 | 2002-07-04 | C. Michael Gosnell | Chromogenic media containing blood or hemin |
US7319031B2 (en) | 2002-11-27 | 2008-01-15 | 3M Innovative Properties Company | Mounting platform for biological growth plate scanner |
US7298885B2 (en) | 2002-11-27 | 2007-11-20 | 3M Innovative Properties Company | Biological growth plate scanner with automated image processing profile selection |
JP2006025608A (ja) | 2004-07-12 | 2006-02-02 | Chisso Corp | 微生物培地 |
FR2897874B1 (fr) * | 2006-02-28 | 2013-11-15 | Biomerieux Sa | Procede pour l'identification d'au moins deux groupes de microorganismes |
FR2936816B1 (fr) | 2008-10-08 | 2013-03-22 | Biomerieux Sa | Milieu reactionnel pour les bacteries staphylococcus aureus resistantes a la meticilline (mrsa) |
US8828682B2 (en) * | 2008-12-09 | 2014-09-09 | 3M Innovative Properties Company | Methods and articles for detecting hemolytic microorganisms |
CN102713616B (zh) * | 2009-12-30 | 2014-10-15 | 3M创新有限公司 | 微生物检测制品 |
BR112013016757B1 (pt) * | 2010-12-30 | 2020-02-18 | 3M Innovative Properties Company | Método para detectar a presença ou ausência de um micro-organismo alvo |
US8921067B2 (en) * | 2013-02-04 | 2014-12-30 | 3M Innovative Properties Company | Method and culture device for detecting yeasts and molds |
-
2015
- 2015-03-05 AU AU2015227127A patent/AU2015227127B2/en not_active Expired - Fee Related
- 2015-03-05 US US15/123,272 patent/US20170073629A1/en not_active Abandoned
- 2015-03-05 CN CN201580012546.1A patent/CN106103689A/zh active Pending
- 2015-03-05 EP EP15710377.1A patent/EP3114209B1/en active Active
- 2015-03-05 WO PCT/US2015/018844 patent/WO2015134686A1/en active Application Filing
- 2015-03-05 KR KR1020167027416A patent/KR102436447B1/ko active IP Right Grant
- 2015-03-05 CA CA2941689A patent/CA2941689A1/en not_active Abandoned
- 2015-03-05 EP EP19176771.4A patent/EP3553163A1/en active Pending
- 2015-03-05 CN CN202210173734.4A patent/CN114592031A/zh active Pending
- 2015-03-05 MX MX2016011466A patent/MX2016011466A/es unknown
- 2015-03-05 JP JP2016573678A patent/JP2017506916A/ja active Pending
- 2015-03-05 BR BR112016020570-7A patent/BR112016020570B1/pt active IP Right Grant
-
2019
- 2019-12-25 JP JP2019233906A patent/JP7115806B2/ja active Active
-
2020
- 2020-12-10 US US17/117,348 patent/US11414641B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
US11414641B2 (en) | 2022-08-16 |
BR112016020570B1 (pt) | 2021-10-13 |
BR112016020570A2 (ko) | 2017-08-15 |
AU2015227127B2 (en) | 2017-09-14 |
US20170073629A1 (en) | 2017-03-16 |
KR102436447B1 (ko) | 2022-08-24 |
EP3114209A1 (en) | 2017-01-11 |
JP7115806B2 (ja) | 2022-08-09 |
EP3553163A1 (en) | 2019-10-16 |
KR20160130443A (ko) | 2016-11-11 |
US20210087516A1 (en) | 2021-03-25 |
CN114592031A (zh) | 2022-06-07 |
EP3114209B1 (en) | 2019-06-12 |
CN106103689A (zh) | 2016-11-09 |
JP2017506916A (ja) | 2017-03-16 |
JP2020072687A (ja) | 2020-05-14 |
WO2015134686A1 (en) | 2015-09-11 |
MX2016011466A (es) | 2016-11-16 |
AU2015227127A1 (en) | 2016-09-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US11414641B2 (en) | Article and method for detecting aerobic bacteria | |
JP6796632B2 (ja) | 酵母菌及びカビを検出するための方法及び培養装置 | |
US20150010941A1 (en) | Detection of acid-producing bacteria | |
US20200399574A1 (en) | Water-reconstitutable culture medium resistant to liquefaction by microorganisms | |
WO2018187195A1 (en) | Rapid detection of e. coli in a thin film culture device | |
EP3607083B1 (en) | Rapid detection of e. coli in a thin film culture device |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Discontinued |
Effective date: 20210831 |
|
FZDE | Discontinued |
Effective date: 20210831 |