CA2940983A1 - Use of eribulin and mtor inhibitors as combination therapy for the treatment of cancer - Google Patents
Use of eribulin and mtor inhibitors as combination therapy for the treatment of cancer Download PDFInfo
- Publication number
- CA2940983A1 CA2940983A1 CA2940983A CA2940983A CA2940983A1 CA 2940983 A1 CA2940983 A1 CA 2940983A1 CA 2940983 A CA2940983 A CA 2940983A CA 2940983 A CA2940983 A CA 2940983A CA 2940983 A1 CA2940983 A1 CA 2940983A1
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- CA
- Canada
- Prior art keywords
- cancer
- pharmaceutically acceptable
- acceptable salt
- eribulin
- everolimus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
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- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
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- A—HUMAN NECESSITIES
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Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| US201461947398P | 2014-03-03 | 2014-03-03 | |
| US61/947,398 | 2014-03-03 | ||
| PCT/US2015/018335 WO2015134399A1 (en) | 2014-03-03 | 2015-03-02 | Use of eribulin and mtor inhibitors as combination therapy for the treatment of cancer |
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| CA2940983A1 true CA2940983A1 (en) | 2015-09-11 |
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| CA2940983A Abandoned CA2940983A1 (en) | 2014-03-03 | 2015-03-02 | Use of eribulin and mtor inhibitors as combination therapy for the treatment of cancer |
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| WO (1) | WO2015134399A1 (enExample) |
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| PL2522663T3 (pl) | 2004-06-03 | 2015-08-31 | Eisai R&D Man Co Ltd | Produkty pośrednie do otrzymywania halichondryny B |
| KR101495951B1 (ko) | 2009-03-30 | 2015-02-25 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 리포솜 조성물 |
| KR102265952B1 (ko) | 2013-06-26 | 2021-06-16 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 암 치료 병용요법으로서 에리불린 및 렌바티닙의 용도 |
| EP3449921B1 (en) * | 2016-04-28 | 2023-05-31 | Eisai R&D Management Co., Ltd. | Eribulin for inhibiting tumor growth |
| US11419856B2 (en) | 2017-11-20 | 2022-08-23 | Basilea Pharmaceutica International AG | Pharmaceutical combinations for use in the treatment of neoplastic diseases |
| WO2020097625A1 (en) * | 2018-11-09 | 2020-05-14 | G1 Therapeutics, Inc. | Therapeutic regimens for treatment of cancer using eribulin and selective cdk4/6 inhibitor combinations |
| US12036204B2 (en) | 2019-07-26 | 2024-07-16 | Eisai R&D Management Co., Ltd. | Pharmaceutical composition for treating tumor |
| US11083705B2 (en) | 2019-07-26 | 2021-08-10 | Eisai R&D Management Co., Ltd. | Pharmaceutical composition for treating tumor |
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| CN101415409B (zh) * | 2006-04-05 | 2012-12-05 | 诺瓦提斯公司 | 用于治疗癌症的治疗剂的组合 |
| JP6141016B2 (ja) * | 2009-08-27 | 2017-06-07 | バイオノミックス リミテッド | 増殖性疾患の治療のための併用療法 |
| JP2014508165A (ja) * | 2011-03-02 | 2014-04-03 | モルフォテック、インク． | 乳癌の治療のためのエリブリンおよびファーレツズマブの共投与 |
| JP2015514113A (ja) * | 2012-04-02 | 2015-05-18 | メリマック ファーマシューティカルズ インコーポレーティッド | 単一特異性および二重特異性抗ｉｇｆ−１ｒおよび抗ｅｒｂｂ３抗体の用法および用量 |
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| KR20160135230A (ko) | 2016-11-25 |
| SG11201607298QA (en) | 2016-09-29 |
| EP3113775A4 (en) | 2017-08-23 |
| WO2015134399A1 (en) | 2015-09-11 |
| JP2017507151A (ja) | 2017-03-16 |
| AU2015225436A1 (en) | 2016-09-08 |
| IL247586A0 (en) | 2016-11-30 |
| CN106029070A (zh) | 2016-10-12 |
| RU2016136504A (ru) | 2018-04-03 |
| US20170071903A1 (en) | 2017-03-16 |
| EP3113775A1 (en) | 2017-01-11 |
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