AU2015225436A1 - Use of eribulin and mTOR inhibitors as combination therapy for the treatment of cancer - Google Patents
Use of eribulin and mTOR inhibitors as combination therapy for the treatment of cancer Download PDFInfo
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- AU2015225436A1 AU2015225436A1 AU2015225436A AU2015225436A AU2015225436A1 AU 2015225436 A1 AU2015225436 A1 AU 2015225436A1 AU 2015225436 A AU2015225436 A AU 2015225436A AU 2015225436 A AU2015225436 A AU 2015225436A AU 2015225436 A1 AU2015225436 A1 AU 2015225436A1
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- Prior art keywords
- cancer
- pharmaceutically acceptable
- acceptable salt
- eribulin
- everolimus
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- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
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- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A—HUMAN NECESSITIES
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- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
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- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| US201461947398P | 2014-03-03 | 2014-03-03 | |
| US61/947,398 | 2014-03-03 | ||
| PCT/US2015/018335 WO2015134399A1 (en) | 2014-03-03 | 2015-03-02 | Use of eribulin and mtor inhibitors as combination therapy for the treatment of cancer |
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| AU2015225436A1 true AU2015225436A1 (en) | 2016-09-08 |
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| US (1) | US20170071903A1 (enExample) |
| EP (1) | EP3113775A4 (enExample) |
| JP (1) | JP2017507151A (enExample) |
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| CA (1) | CA2940983A1 (enExample) |
| IL (1) | IL247586A0 (enExample) |
| RU (1) | RU2016136504A (enExample) |
| SG (1) | SG11201607298QA (enExample) |
| WO (1) | WO2015134399A1 (enExample) |
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| CN101899026B (zh) | 2004-06-03 | 2016-08-03 | 卫材R&D管理有限公司 | 用于制备软海绵素b的类似物的中间体 |
| SI2415470T1 (sl) | 2009-03-30 | 2016-12-30 | Eisai R&D Management Co., Ltd. | Liposomski sestavek |
| ES2705698T3 (es) | 2013-06-26 | 2019-03-26 | Eisai R&D Man Co Ltd | Terapia de combinación para el tratamiento del cáncer que comprende eribulina y lenvatinib |
| EP3449921B1 (en) * | 2016-04-28 | 2023-05-31 | Eisai R&D Management Co., Ltd. | Eribulin for inhibiting tumor growth |
| WO2019097073A1 (en) | 2017-11-20 | 2019-05-23 | Basilea Pharmaceutica International AG | Pharmaceutical combinations for use in the treatment of neoplastic diseases |
| CN113271977A (zh) * | 2018-11-09 | 2021-08-17 | G1治疗公司 | 使用艾日布林和选择性cdk4/6抑制剂组合治疗癌症的治疗方案 |
| US11083705B2 (en) | 2019-07-26 | 2021-08-10 | Eisai R&D Management Co., Ltd. | Pharmaceutical composition for treating tumor |
| US12036204B2 (en) | 2019-07-26 | 2024-07-16 | Eisai R&D Management Co., Ltd. | Pharmaceutical composition for treating tumor |
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| WO2007124252A2 (en) * | 2006-04-05 | 2007-11-01 | Novartis Ag | Combinations of therapeutic agents for treating cancer |
| AU2010286334B2 (en) * | 2009-08-27 | 2016-02-04 | Bionomics Limited | Combination therapy for treating proliferative diseases |
| EP2680839A1 (en) * | 2011-03-02 | 2014-01-08 | Morphotek, Inc. | Co -administration of eribulin and farletuzumab for the treatment of breast cancer |
| KR20140148412A (ko) * | 2012-04-02 | 2014-12-31 | 메리맥 파마슈티컬즈, 인크. | 단일특이적 및 이중특이적인 항-igf-1r 및 항-erbb3 항체의 용량 및 투여 |
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2015
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- 2015-03-02 US US15/123,476 patent/US20170071903A1/en not_active Abandoned
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- 2015-03-02 EP EP15758504.3A patent/EP3113775A4/en not_active Withdrawn
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- 2015-03-02 RU RU2016136504A patent/RU2016136504A/ru unknown
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Also Published As
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|---|---|
| WO2015134399A1 (en) | 2015-09-11 |
| SG11201607298QA (en) | 2016-09-29 |
| KR20160135230A (ko) | 2016-11-25 |
| RU2016136504A (ru) | 2018-04-03 |
| EP3113775A4 (en) | 2017-08-23 |
| CN106029070A (zh) | 2016-10-12 |
| CA2940983A1 (en) | 2015-09-11 |
| US20170071903A1 (en) | 2017-03-16 |
| RU2016136504A3 (enExample) | 2018-10-25 |
| EP3113775A1 (en) | 2017-01-11 |
| IL247586A0 (en) | 2016-11-30 |
| JP2017507151A (ja) | 2017-03-16 |
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