CA2915671A1 - High potency pancreatin pharmaceutical compositions - Google Patents

High potency pancreatin pharmaceutical compositions Download PDF

Info

Publication number
CA2915671A1
CA2915671A1 CA2915671A CA2915671A CA2915671A1 CA 2915671 A1 CA2915671 A1 CA 2915671A1 CA 2915671 A CA2915671 A CA 2915671A CA 2915671 A CA2915671 A CA 2915671A CA 2915671 A1 CA2915671 A1 CA 2915671A1
Authority
CA
Canada
Prior art keywords
pancreatin
solvent
mixture
mpa
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA2915671A
Other languages
English (en)
French (fr)
Inventor
Stephen Perrett
Robert Becker
Luigi Boltri
Luigi Ghidorsi
Paola ARZUFFI
Vincenza Pironti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Allergan Pharmaceuticals International Ltd
Aptalis Pharma SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=53042009&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2915671(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Allergan Pharmaceuticals International Ltd, Aptalis Pharma SRL filed Critical Allergan Pharmaceuticals International Ltd
Publication of CA2915671A1 publication Critical patent/CA2915671A1/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/94—Pancreatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Nutrition Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CA2915671A 2013-11-05 2014-11-05 High potency pancreatin pharmaceutical compositions Pending CA2915671A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361900092P 2013-11-05 2013-11-05
US61/900,092 2013-11-05
PCT/US2014/063984 WO2015069677A1 (en) 2013-11-05 2014-11-05 High potency pancreatin pharmaceutical compositions

Publications (1)

Publication Number Publication Date
CA2915671A1 true CA2915671A1 (en) 2015-05-14

Family

ID=53042009

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2915671A Pending CA2915671A1 (en) 2013-11-05 2014-11-05 High potency pancreatin pharmaceutical compositions

Country Status (13)

Country Link
EP (2) EP3613429A1 (https=)
JP (1) JP2017500885A (https=)
KR (1) KR20170052520A (https=)
CN (1) CN106659773A (https=)
AU (1) AU2014346930A1 (https=)
BR (1) BR112016000658A2 (https=)
CA (1) CA2915671A1 (https=)
ES (1) ES2834483T3 (https=)
HK (1) HK1222325A1 (https=)
IL (3) IL243435B (https=)
MX (1) MX2016000480A (https=)
RU (1) RU2015155470A (https=)
WO (1) WO2015069677A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1319655B1 (it) 2000-11-15 2003-10-23 Eurand Int Microsfere di enzimi pancreatici con elevata stabilita' e relativometodo di preparazione.
US8246950B2 (en) 2007-02-20 2012-08-21 Aptalis Pharma Limited Stable digestive enzyme compositions
WO2009109856A2 (en) 2008-03-07 2009-09-11 Axcan Pharma Inc. Method for detecting infectious parvovirus in pharmaceutical preparations
UA111726C2 (uk) 2010-10-01 2016-06-10 Апталіс Фарма Лімітед Препарат панкреліпази низької сили з кишковорозчинним покриттям
CA2843556A1 (en) 2011-08-08 2013-02-14 Aptalis Pharma Ltd. Method for dissolution testing of solid compositions containing digestive enzymes
WO2015019198A2 (en) 2013-07-22 2015-02-12 Aptalis Pharma S.R.L. High potency pancreatin pharmaceutical compositions
MX2016001593A (es) 2013-08-09 2016-09-29 Allergan Pharmaceuticals Int Ltd Composicion de enzima digestiva adecuada para administracion enterica.
JP2017519490A (ja) * 2014-06-19 2017-07-20 アプタリス ファルマ リミテッド 膵臓抽出物からのウイルス汚染の除去方法

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2751330A (en) * 1952-08-27 1956-06-19 Armour & Co Use of a salt in the extraction slurry in recovering proteolytic enzymes from pancreas gland material
GB928654A (en) 1960-10-25 1963-06-12 Philips Nv Improvements in or relating to the production of pancreatin
US3168448A (en) 1963-01-07 1965-02-02 Wilson & Co Inc Process of preparing a lipolytic enzyme composition
DE2460334C3 (de) * 1974-12-20 1979-09-06 Hoechst Ag, 6000 Frankfurt Verfahren zur Gewinnung von Insulin und Pankreatin aus Schweinepankreas
EP0115023B1 (de) * 1982-12-30 1988-07-27 Nordmark Arzneimittel GmbH Verfahren zur Gewinnung von Pankreatin
FR2603804B1 (fr) * 1986-09-17 1989-10-27 Jouveinal Sa Lipases et extraits lipasiques, leur procede de preparation et leur application en therapeutique
DE3927286C2 (de) * 1989-08-18 1997-07-24 Roehm Gmbh Wäßrige Enzym-Flüssigformulierungen
US6051220A (en) 1995-05-31 2000-04-18 Medzyme N.V. And Simon Lodewijk Scharpe Composition to improve digestibility and utilization of nutrients
US5750104A (en) * 1996-05-29 1998-05-12 Digestive Care Inc. High buffer-containing enteric coating digestive enzyme bile acid compositions and method of treating digestive disorders therewith
DE19724845A1 (de) * 1996-08-28 1998-03-05 Solvay Pharm Gmbh Verwendung von komplexen Lipiden als stabilisierende Zusätze zu pharmazeutischen Zubereitungen von Verdauungsenzymgemischen
US20010046493A1 (en) 2000-02-24 2001-11-29 Alex Margolin Lipase-containing composition and methods of use thereof
AR032392A1 (es) * 2001-01-19 2003-11-05 Solvay Pharm Gmbh Mezcla de enzimas, preparado farmaceutico y utilizacion de dicho preparado.
CA2419572A1 (en) * 2003-02-18 2004-08-18 Axcan Pharma Inc. High dosage protease formulation
US20060198838A1 (en) * 2004-09-28 2006-09-07 Fallon Joan M Combination enzyme for cystic fibrosis
PT1809320E (pt) * 2004-10-14 2010-10-25 Altus Pharmaceuticals Inc Composições contendo lipase, protease e amilase para o tratamento de insuficiência pancreática
HUE031042T2 (en) 2005-07-29 2017-06-28 Abbott Laboratories Gmbh Methods for producing pancreatin powder with low viral content
US8246950B2 (en) * 2007-02-20 2012-08-21 Aptalis Pharma Limited Stable digestive enzyme compositions
RU2012142134A (ru) * 2010-03-19 2014-04-27 Апталис Фарма Кэнэда Инк. Желудочно-резистентные ферментные фармацевтические композиции
AU2011248293A1 (en) * 2010-05-03 2012-11-15 Eurand Pharmaceuticals Limited Micropellet compositions comprising pancreatin containing digestive enzyme mixtures
UA111726C2 (uk) * 2010-10-01 2016-06-10 Апталіс Фарма Лімітед Препарат панкреліпази низької сили з кишковорозчинним покриттям
CN103060297B (zh) * 2012-12-28 2014-06-25 青岛九龙生物医药有限公司 一种分离纯化胰蛋白酶的方法
CN103060296B (zh) * 2012-12-30 2014-05-21 青岛九龙生物医药有限公司 从动物胰脏中提取胰蛋白酶的方法
WO2015019198A2 (en) 2013-07-22 2015-02-12 Aptalis Pharma S.R.L. High potency pancreatin pharmaceutical compositions

Also Published As

Publication number Publication date
IL243435A0 (en) 2016-03-31
AU2014346930A1 (en) 2016-01-07
EP3613429A1 (en) 2020-02-26
MX2016000480A (es) 2016-10-21
HK1222325A1 (zh) 2017-06-30
EP3003360A4 (en) 2017-04-26
IL274583A (en) 2020-06-30
IL243435B (en) 2020-06-30
WO2015069677A1 (en) 2015-05-14
JP2017500885A (ja) 2017-01-12
IL284419A (en) 2021-07-29
IL274583B (en) 2022-06-01
RU2015155470A3 (https=) 2018-09-10
CN106659773A (zh) 2017-05-10
RU2015155470A (ru) 2017-08-21
KR20170052520A (ko) 2017-05-12
BR112016000658A2 (pt) 2018-03-20
EP3003360A1 (en) 2016-04-13
EP3003360B1 (en) 2020-10-07
ES2834483T3 (es) 2021-06-17

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